803 search results for “brain” in the Public website
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Magnetic Resonance Microimaging of Alzheimer's Disease
Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…
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Singing is silver, hearing is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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Research methods
Because we cannot directly ask babies about what they know or what they are thinking about, we must find smart and baby-friendly ways to figure it out! Below you can read about the different methods that we typically use in our studies.
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Choosing health: how do we encourage that?
Fundamental research teaches us how our brain decides to eat one more sweet, instead of doing exercise. A public information campaign about healthy lifestyle has little impact on the decision, as Professor of General Psychology Bernard Hommel is aware. However, he does know what works. But the question…
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Roy de Kleijn: ‘Fetching a glass of water is extremely difficult for a robot’
Training a robot in a real-life environment is more or less impossible. Computer scientist and psychologist Roy de Kleijn switched to training in a simulated, virtual one instead. ‘You do have a reality gap, but the more precisely you train the robot, the better it is in practice.’ His inspiration:…
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Topic: Aging and neuropsychological rehabilitation
Cognitive decline (amongst other problems with attention, concentration, memory) is a common symptom in patients with a variety of brain disorders and has been related to healthy ageing as well. People suffering from cognitive deficits are often significantly hampered in their day-to-day functioning…
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Membership LIBC
All brain and/or cognition researchers from Leiden University or the LUMC or colleagues seeking collaboration in this field are most welcome to join the LIBC!
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Neurofibromatosis Type I
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Unraveling the Neural Basis of Self-Esteem in Adolescent Depression
What are the social and neural mechanisms that contribute to fluctuations in self-esteem in healthy adolescents and adolescents with depression?
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Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands
Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Why more women have ADHD than you think
When we think of ADHD, we often think of highly creative, hyperactive boys. But does this mean that girls don’t have ADHD at all?
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Clinical Neuropsychology (MSc)
In the specialisation Clinical Neuropsychology, part of the Master in Psychology, you will focus on fostering clinical and scientific skills based on a solid theoretical background as well as practical training in neuropsychology and (clinical) neuropsychological research.
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Developing your own self-image and choosing the right study programme
How you think about yourself is important for the choices you make. Adolescents are faced with choosing a study programme that will determine their future, while their self-image is still under development. Tough choice? Research by psychologist Laura van der Aar has shown that taking a training course…
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‘LIBC Junior is bursting with new ideas’
How does the brain develop from birth up to adolescence? And why are young people given so little information about the development of their brain? Two new websites of the Leiden Institute for Brain and Cognition provide an answer.
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Influence of dissociation on the neural correlates of Emotional Working Memory in Borderline Personality Disorder
How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?
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Changing minds in social anxiety: A developmental network approach to neurocognitive bias modification
Which adolescents are more at risk of developing social anxiety disorder later in life?
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AI in Neuroscience: Development of Methods to make Personalized Predictions for Migraine and Stroke from E-Health Sensor Data
The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.
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Solving problems in your head and in the world
Until recently, the role of external information processing in intelligence has rarely been investigated quantitatively or experimentally. A group of researchers from Erasmus University Rotterdam, Leiden University, GGZ Rivierduinen, and University of Edinburgh measured in a new way how and when people…
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Participate
The researchers of the Brain and Education Lab are always conducting or starting new research projects in the field of learning and brain development. For this they are often looking for children, adolescents and adults between 8 and 30 years old who want to help and participate. Several research projects…
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Spatial (3-D) CNS drug distribution in vivo
Another research line is the development of a spatial CNS drug distribution model, by ultimately including the 3-dimensional anatomical organization of the CNS.
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LIBC Support
The LIBC is a network focusing on science valorisation and outreach, stimulating interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition. Get to know the support team.
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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Developmental Psychology (research) (MSc)
The Developmental Psychology specialisation of the Research Master’s in Psychology offers a strong theoretical background to provide the varied knowledge-base needed for a thorough understanding of emotional and cognitive development across childhood and adolescence.
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Experiments on the Modular Nature of Word and Sentence Phonology in Chinese Broca's Patients
This book investigates the effects of brain lesions in the left hemisphere, specifically Broca's area, on the production and perception of vowels, of word tones and of the linguistic use of sentence melody.
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Topic: Spatial thinking
Our everyday life consists of all sorts of spatial processes: we find our way to work, remember where we left our keys, and are able to pick up our cup of coffee. We study how the human brain processes such spatial processes. From a clinical perspective, we are interested in how acquired brain damage…
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Lab facilities Developmental and Educational Psychology
Social anxiety and factors determining school success in children. Brain development in relation to cognitive, social and emotional development in adolescence.
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
- Young Academy Leiden Outreach Grant
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Humans of Psychology
For Humans of Psychology, students and staff will be put into the spotlight. At our institute prizes are won, exiting research is conducted, knowledge is harnessed, public meeting are organised and open science is highlighted. Take a look behind the scenes.
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The exciting migraine brain, towards neurophysiological prediction of migraine attacks
PhD defence
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Flow-based Arterial Spin Labeling: From brain to body
PhD defence
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Imaging the prenatal brain in congenital heart defects
PhD defence
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They're going on a parabolic flight - and you can go too!
Always wanted to find out what zero gravity is like? Now's your chance! In December 2017 a Dutch student team will be conducting experiments during a parabolic flight, and they're looking for healthy volunteers. You do have to meet a number of strict conditions, says the team leader.
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Veni award for psychologist Barbara Braams
Developmental psychologist Barbara Braams has been awarded with a Veni funding for her research about risk behaviour in young people. This award offers Braams the opportunity to develop her ideas over a period of three years.
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Contact
General contact information.
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LIBC Meetings & Events
The LIBC organizes a yearly LIBC Public Scientific Day, Colloquia, Sylvius Lectures and so on.
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Research
The Institute of Psychology is responsible for innovative and interdisciplinary research and education within psychology and related disciplines. It focuses primarily on four broad areas: Health and Wellbeing; Development and Learning; Socio-Cognitive-Affective Decision-making and Advanced Behavioural…
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24-hour rhythms in drug exposure and effect
Although rarely considered by the pharmaceutical industry or clinicians, 24-hour rhythms in physiology are a factor of potential influence on the pharmacokinetics and pharmacodynamics of drugs.
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Born to be shy?
An international mega-analysis on the neurobiological link between inhibited temperament and social anxiety disorder
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Cognitive enhancement: Toward the integration of theory and practice
Cognitive enhancement reflects the use of any (legitimate) means such as for example food supplements to reach one’s personal best.
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Topic: Movement and mental functions
Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.
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Supramolecular & Biomaterials Chemistry
The Supramolecular & Biomaterials Chemistry group comprises the PIs Alexander Kros, Roxanne Kieltyka, Gregory Schneider and Sander Wezenberg, and is active in the field of self-assembly of amphiphilic peptides and applying them in supramolecular chemistry.
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HOPES Study
The HOPES study is one of the largest investigations of this kind to date! By studying existing brain scans and data collected form over 4,000 14-25 year olds, the project team hopes to identify specific changes in the brain that make young people vulnerable to suicidal thoughts and behaviours.
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Self-regulation in boys with ODD/CD
Understanding individual differences in self-regulation in boys with ODD/CD on the level of brain, cognition and behavior
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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474, SCIENCE, 2017
The drug BIA 10-2474 inhibits fatty acid amide hydrolase (FAAH), a lipase that degrades a specific endocannabinoid. On the basis of this activity, BIA 10-2474 was being developed as a potential treatment for anxiety and pain. In a phase 1 trial of the drug, one subject died, and four others suffered…
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Health, Medical and Neuropsychology
The unit Health, Medical and Neuropsychology offers eduction and conducts research on related fields of Health, Medical and Neuropsychology.