Researchers of the Leiden Institute of Advanced Computer Science (LIACS) will develop a training programme the next generation of early stage researchers (ESRs). During a four years project they will be trained to approach industrial challenges in a holistic manner by developing solutions in an automotive…

This thesis proposes multiple paths towards the development of a performance practice in Computer Music.

Data analysis with Python and R are rapidly becoming essential skills for modern scientists. Therefore, we are offering courses to develop your scientific computing skills. Those courses are optional for LACDR PhD candidates.

The research of our group is centered around dynamical systems, functional analysis and their interplay.

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

ChatGPT, translation machines and bots: for Carole Tiberius, they are a piece of cake. On 1 January, she was appointed professor of Computational Linguistics. 'There ae two elements to the field: computer science and linguistics.'

Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.

The two-years master’s specialisation System Biomedicine and Pharmacology at Leiden university focuses on predicting drug response with computational modelling, developing individualised therapies, and developing innovative analytical tools for personalised health strategies.

Accelerating the diagnosis and personalising the management of inherited metabolic diseases.

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.

Students in Leiden are entitled to good teaching and good supervision. For their part, there are some conditions they have to meet to ensure that they complete their studies within the time allotted.

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

The research of this programme is centered around dynamical systems, functional analysis, and their interplay.

Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

Interaction between Legal Systems acknowledges that law-making and law enforcement are increasingly taking place on various levels: in a global context, in EU context, on a national level and in a private law framework. These levels influence each other, sometimes directly, on the basis of a hierarchical…

How do balanced lethal systems originate and persist in nature?

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

Science, Mathematical Institute (MI)

The research groups within the biological, soft and complex systems research area study the physics of a broad range of biological and soft materials. This spans both experimental and theoretical research.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

We study the physics of a broad range of biological and soft materials

This book explores the boundaries of the category of gender and their theoretical significance within the framework of Canonical Typology.

Grammatical gender is famously the most puzzling of the grammatical categories. We have a solid typology of gender systems, yet exciting and unexpected patterns keep turning up which defy easy classification and straightforward analysis. Some of these question, stretch or threaten to cross the outer…

Duality, stochastic processes

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

At Leiden University we believe it is important that you receive the right kind of support in your choice of study and while you study. This is why we use what we call the ‘Leiden study system’ to help you make a success of your study from start to finish.

This interdisciplinary research project explores several adaptive machine learning methods which can give insight into the interaction between human and machine. The ultimate goal is open and natural communication between humans and AI that should result in mutual trust, cooperation and coordination…

Natural Computing is the field of research that investigates both human-designed computing inspired by nature and computing taking place in nature, i.e., it investigates models and computational techniques inspired by nature and also it investigates phenomena taking place in nature in terms of information…

Nonparametric Bayes for high-dimensional models: contraction, credible sets, computations

Most of current public-key cryptography is considered insecure against attacks from sufficiently powerful quantum computers. Post-quantum cryptography studies methods to secure information resistant against such attacks. One proposal is isogeny-based cryptography, which bases its security on computational…

We review the state-of-the-art in the theory of dissociative chemisorption (DC) of small gas phase molecules on metal surfaces, which is important to modeling heterogeneous catalysis for practical reasons, and for achieving an understanding of the wealth of experimental information that exists for this…

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

Science, Leiden Institute of Advanced Computer Science (LIACS)

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Research into research improves the academic system. CWTS studies and evaluates the academic system in various ways. One way is to provide information on the productivity and impact of academics by documenting how many publications they or their universities produce and how often these publications…

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

In this article, Marco Cinelli, assistant professor at Leiden University College The Hague, examines proper and improper uses of Multiple Criteria Decision Analysis (MCDA) methods in energy systems analysis.

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Can we use quantum computers in a way that is also relevant to society? With the help of a 2-million-euro NWA grant, Leiden University will work with partners such as Surf, Google and Volkswagen to demonstrate that quantum computers are also of value outside the lab.

An important hormone excreting gland in the human body is the pituitary