327 search results for “differentiation” in the Public website
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Cellular Forces: Adhering, Shaping, Sensing and Dividing
Promotor: Prof.dr. T. Schmidt
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Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
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About the programme
The Mathematics and Algebra, Geometry and Number Theory specialisation programme consists of 120 European Credit Transfer System (EC) points and includes a research project (40 EC), advanced courses (min 60 EC) and electives (maximum 20 EC). 30 EC are to be taken from the Dutch national Mastermath p…
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About the programme
The Applied Mathematics Programme consists of 120 European Credit Transfer System (EC) points. The programme consists of advanced courses (min 60 EC), a research project (40 EC) and electives (max 20 EC).
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Programme structure
The research specialisation offers you the opportunity to spend two full years on training in applied mathematics to become an independent scientist with a strong theoretical basis.
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Liko Phonology and Grammar. A Bantu language of the Democratic Republic of the Congo
This thesis presents a detailed description of the phonology, the tone system and the grammar of Liko, a Bantu language spoken by about 70,000 people in the northeastern part of the Democratic Republic of the Congo. It provides numerous examples.
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Designing 'context-specific' regional innovation policy: a study on the role of regional government in six European regions
Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…
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Chromatin organization & dynamics (Dr. Remus Dame)
Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…
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Diversity in parenting and education
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Global Interactions
How does global change across time and space lead to convergence and loss of variation or increasing diversity and conflict?
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Online price discrimination, justice and regulation
The data-driven economy allows for the collection and processing of large amounts of data. Such data can be used to optimize profits by (dynamically) differentiating prices for different consumers.
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Macrophages and atherosclerotic lesions
Macrophages and atherosclerotic lesions The infiltration of monocytes in the arterial wall, their differentiation to macrophages, and the subsequent accumulation of cholesterol in these macrophages initiate the process of atherosclerosis. We study the importance of specific genes in macrophages for…
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Case studies
The research that is united in the Liveable Planet programme, touches upon a wide range of aspects of human life. The goal is to deepen and expand the scope and to connect more researchers. The following case studies are examples of current research projects.
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About
The unique geographic and temporal breadth of research at Leiden allows us to stimulate a shift from the classical Weberian mode of scholarly production that views historical development and modernization as emanating from Europe and the West to a multi-polar perspective that allows for more nuanced,…
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The Performative Force of Accented Speech: Language, Body, and Violence
This research examines the social, political, and cultural forces that structure people’s responses towards accented speech, and further uses the accent as a focal point to theorize the interrelation between language and body.
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Ulama and the State in Modern Aceh
On 21 September 2022 Arfiansyah successfully defended a doctoral thesis and graduated.
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Gendered impacts of industrial logging
This study focuses on the local level impacts of a highly globalised industry: the international trade in tropical timber.
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The recognition process of youth with problematic anxiety in general practice
Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?
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Research and design in STEM education
Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…
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The economic geography of Roman Italy
Can we identify different degrees of economic integration, both within and between regions, on the basis of archaeological proxies?
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Human nature and governance: soulcraft and statecraft in eleventh century China
On the 2nd of September Jiyan Qiao successfully defended a doctoral thesis and graduated.
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What accounts for the variation in COVID-19 vaccine hesitancy in Eastern, Southern and Western Europe?
In this article, Dimiter Toshkov investigates the determinants of COVID-19 vaccine hesitancy and refusal, focusing on Eastern, Southern and Western Europe.
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.
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Molecular, Cellular and Organismal Biology (MSc)
The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.
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Mathematics (MSc)
The master’s programme Mathematics at Leiden University focuses on analysis, probability and statistics, number theory and (arithmetic) geometry. It offers five specialisations ranging from Applied Mathematics to Mathematics and Business Studies.
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Applied Mathematics (MSc)
The master's specialisation Applied Mathematics at Leiden University focuses on both computational and fundamental aspects of analysis and probability. It’s also an ideal basis for a PhD degree. Applied Mathematics is an excellent choice if you have the aspiration to pursue a PhD degree
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Micha Drukker
Science
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Development of life cycle assessment for residue-based bioenergy
What are the key issues in conducting LCA of bioenergy systems? What is the environmental sustainability status of second generation bioethanol? How much would the final results of biogenic carbon neutrality assumptions deviate from the true values based on a complete inventory? How to assess the impact…
- Cultural Diplomacy
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Excavating Chlorakas-Palloures
Investigating the emergence of complex societies in Chalcolithic Cyprus.
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Project SENSYN
Making sensitive data reusable through synthetic data generation
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Research
Urban, Food, Water, Biodiversity, Resources and Energy: these are the main research topics of the Institute of Environmental Sciences. We always strive to be a global leader in our field. And make a real impact with both our research programmes.
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Research
The aim of the research programme is to provide insight into the cognitive processes and brain mechanisms that underlie reading, arithmetic and learning in general.
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Neurodevelopmental risks in young children with an extra X or Y chromosome
This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.
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Articulating Modernity: The Making of Popular Music in 20th Century Southeast Asia and the Rise of New Audiences.
Who were the main artists and producers who generated new forms of popular music? What was the music like that was produced by artists in particular urban settings? How were particular lifestyles articulated to identify new audiences and what does this reveal about the way popular music contributed…
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I will maintain, enforce and uphold. Exploration into pluralization of policing functions.
The Directorate-General Police, Sanctions, and Protection has initiated this research project in order to gain insight in the nature and, if possible, the extent of the developments with regards to the pluralization of policing functions in the Netherlands in support of future policies for the benefit…
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Constructing monuments, perceiving monumentality and the economics of building
The goal of this book is to place architectural studies, in which people’s interactions with each other and material resources are key, at the crossing of both landscape studies and material culture studies, where it belongs.
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Short intensive session on educational development
Didactics
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Connecting in times of duress: understanding communication and conflict in Middle Africa’s mobile margins
This research programme seeks to understand the dynamics in the relationship between social media, mobile telephony and the social fabric under duress in Africa's mobile margins. It combines studies on mobility/migration, conflict and communication in an attempt to uncover these new dynamics, which…
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Mathematical modelling of adverse outcome pathways
In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.
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Scientific research
The effectiveness of the intervention has been examined extensively among different groups of caregivers and children in both the Netherlands and abroad. Among these groups were children in high-risk situations, parents in high-risk situations/extraordinary circumstances and caregivers in childcare.…
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Mathematical Institute
Mathematics forms the basis of many innovations in technology, the service industry and science, such as data analysis and coding, artificial intelligence, weather or climate change modelling or understanding molecular processes. The researchers from the Mathematical Institute (MI) are constantly developing…
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Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
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Egypt
This is an Erasmus+ International Credit Mobility project of Leiden University with the American University in Cairo.
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Leiden Index of Depression Sensitivity
The Leiden Index of Depression Sensitivity (LEIDS) measures cognitive reactivity (CR) to sadness, an aspect of cognitive vulnerability to depression, conceptually similar to rumination.