2,384 search results for “mathematical and statistical modelling” in the Public website
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Johannes Schmidt-Hieber
Science
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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Applied Psychometric and Sociometric Modeling
This research team is concerned with the measurement and modelling of behaviour, cognition, and unobserved traits (e.g., latent variables, missing data). Central aims include the distillation of a complex set of features into lower-dimensional representations (e.g., factor analysis, IRT), determining…
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Mathematics-based strategies for repairing tumour blood vessels
How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?
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Theory-enriched practical knowledge in mathematics teacher education
This study looks at the question of how and at what level students in primary teacher education can integrate theory and practice, and how the organisation of their learning environment, focusing especially on mathematics and pedagogy, can contribute to that.
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Spinoza project Statistical Science
Developing and investigating statistical methods for complex data and models
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Award winners in Methodology and Statistics department
The Department of Methodology and Statistics proudly celebrates the remarkable achievements of two award winners
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Statistics and Data Science
Are you thinking about studying Statistics and Data Science? Learn more and watch the introduction video.
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Mathematics and Education (MSc)
The master’s specialisation Mathematics and Education at Leiden University prepares students to teach the subject of mathematics to secondary school students. The programme comprises a one-year mathematics component, followed by an education component in the second year.
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
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Current challenges in statistical DNA evidence evaluation
Promotor: R.D. Gill, F. Taroni
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Boethius and the Importance of Basic Logic and Mathematics for Philosophy
In this dissertation, Boethius’ mathematics and logic and their roles in philosophy are reassessed, and on the basis of these, the connections between mathematics and logic in Boethius and their applications to theological or philosophical topics are explored.
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Applied statistics as a pillar of data science
Data science is now growing fast in many places, but scholars at Leiden University have been developing data science techniques for a long time already. Thanks to their broad-based expertise, Leiden statisticians are currently combining the achievements in statistics with the latest methods of statistical…
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Statistical Consultation
Welcome to StatiCS: the Statistical Consultation Service. The goal of the service is to provide statistical support to PhD candidates and other researchers.
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Mathematics and Business Studies (MSc)
The master’s specialisation Mathematics and Science Based Business at Leiden University bridges science and business development by focusing on areas such as technology management, innovation, entrepeneurship, operations, and decision making.
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Bayesian Inference for Gaussian Models
This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.
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Prior information and variational Bayes in high dimensional statistical network inference
This thesis develops statistical methods for the analysis of high dimensional data: high dimensional networks reconstruction (Chapters 1-4), incorporation of prior information in networks reconstruction (Chapters 2-4), incorporation of prior knowledge in genetic association studies (Chapter 3).
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Stadium wave in the nerves: a new mathematical model
Electrical signals travel like a wave through our neural pathways. The mathematical models for these movements could not yet properly describe all the biological properties of the nerves. PhD student Willem Schouten-Straatman changed this by improving the existing models. ‘I hope that one day we will…
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reform: an empirical research about the implementation of national mathematics curriculum reform in China
This is a research project on the implementation of national mathematics curriculum reform in Chinese junior high school. The research is expected to provide insight into the ways and reasons of mathematics teachers in Chinese junior high school for implementing national curriculum reform.
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Statistical learning for complex data to enable precision medicine strategies
Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.
- Teaching Mathematics (MSc)
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Numerical exploration of statistical physics
In this thesis, we examine various systems through the lens of several numerical methods.
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Systems Modelling Lab (SML)
Mathematical models of software systems enable characterizations, abstractions, simulations, and analysis of complex software during its development.
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Better Predictions when Models are Wrong or Underspecified
Promotor: P.D. Grünwald
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These researchers turn mathematical models into healthcare solutions
Two Leiden researchers have demonstrated how mathematics can improve our healthcare. Daniel Gomon has developed a model that contributes to the quality of care in hospitals. Marta Spreafico works on an app that helps physicians make well-informed decisions about the treatment of a certain type of cancer.…
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Mathematics and Science Communication and Society (MSc)
The master’s specialisation Mathematics and Science Communication and Society at Leiden University bridges the gap between experts and the public by combining high quality research in mathematics with extensive training in science communication.
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Hannah Bliersbach
Faculteit Rechtsgeleerdheid
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Quantum dot microcavity control of photon statistics
During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.
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Harald van Mil
Science
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Hans Metz
Science
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Lodewijk Kallenberg
Science
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Hans Finkelnberg
Science
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Herman Blok
Science
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Martin Göll
Science
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Serge Fehr
Science
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Student for a Day Mathematics MSc
Study information
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Services on Environmental Statistics and Accounts
What is the best way to combine the environmental and economic data and how can we create an operational system to do so, thereby supporting the delivery of data to the Data centres on Products and Resources?
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Modeling interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
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Robert-Jan Kooman
Science
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Preparing MFDEs for the Modelling World
Classical mathematical models treat space and time as a continuum, while it is sometimes more useful to regard it as granular. Hupkes is studying what this means for a number of important patterns that are often found in computer calculations and in nature.
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Richard Gill
Science
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Jacq Meulman
Science
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Rob Tijdeman
Science
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Kees Verduin
Faculteit der Sociale Wetenschappen
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Mathematical model predicts drug concentration in the brain
Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…
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Quantum local asymptotic normality and other questions of quantum statistics
Promotor: R. Gill, Co-promotor: P. Massart
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Predictive Pharmacology in Children using Semi-Physiological population modelling
An integrated approach of physiological concepts, advanced statistical approaches and large clinical datasets.
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Abstract Behavioral Specification: unifying modeling and programming
We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks