Mathematical biologists from Leiden have developed a model that helps to explain how the spine and vertebrae, among other things, form during embryonic development. The same process, the other way around, plays a key role in cancer metastasis. Publication in iScience.

Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe

The project Deconstructing Stability aims to improve reconstructions of late prehistoric landscapes and predictive models for the purpose of archaeological heritage management.

Alumni event

To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.

The programme group Research Methods and Statistics is part of the Institute of Education and Child Studies. This group is located in the Faculty of Social and Behavioural Sciences of Leiden University near Central Station.

Floske Spieksma will give her inaugural lecture as Professor of Mathematics of Operations Research on 1 September. A discussion about mathematical models, Venezuela, trembling knees, being the only woman, casinos, intuition and above all loving your job.

This dissertation addresses the different use of the same philosophical model: immanent teleology. In this work Aristotle, the founder of the study of final causes, is put in relation with the modern French evolutionary thinker Henri Bergson, the philosopher of time. The dissertation tackles the two…

Which traits did change due to the invasion process of plants and how do these traits contribute to the invasiveness of such species. What is the role of carbohydrate accumulation? What is the function of carbohydrate accumulation in plants? Is genetic variation depleted in invasive species under se…

The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.

Methodology & Statistics offers bachelor's courses and a master's specialisation.

The ability to collect and interpret huge quantities of data has become indispensable to society and academia. Leiden University is a knowledge and expertise centre for data science that places the emphasis on interdisciplinary collaboration and innovation.

Towards a framework that integrates content-based and process-based accounts of mathematical thinking

Marta Fiocco, associate professor at the Mathematical Institute of Leiden University, has signed an agreement with the UWV (the administrative authority that implements employee insurances and provides labour market and data services) to work with their data in the research project

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

Research from weekly magazine Elsevier shows that both the Leiden bachelor Wiskunde as the master Mathematics are rated as the best educational programs of the Netherlands according to professors. The first place was achieved by up to 70% of the votes.

‘Statistics? I hated that hard subject in school’, statistician Sanne Willems is often told. And that is a pity, she thinks, because statistics doesn’t necessarily have to be difficult. Together with two former fellow students, she set up a Statistics Communication section for good communication on…

Promotor: Prof.dr. B.R. Katzy, Co-promotor: R. Ortt

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

From April 2022, Professor Paul Nieuwbeerta will be working one day a week as affiliated professor for Statistics Netherlands (Centraal Bureau voor de Statistiek (CBS)). He is Professor of Criminology at the Institute of Criminal Law and Criminology, Leiden University.

Marta Fiocco has been appointed as of 1 April as professor of applied mathematics, in particular medical statistics. Fiocco's appointment is at the Faculty of Science and at the Leiden University Medical Centre (LUMC). She conducts research into 'personalised medicine', tailor-made medicines for cancer…

Promotores: J. Kok, M. Chaudron (Chalmers University)

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

In this paper, the authors outline how the UK and USA adopt the Chilean pension model without proper attribution, potentially distorting the lessons.

Accelerating the diagnosis and personalising the management of inherited metabolic diseases.

Marta Fiocco, professor in the Mathematical Institute, has received a grant for analysing data on chemotherapy in children suffering from leukaemia. The work involves developing and applying new statistical methods that will help determining the optimal dose of chemotherapy.

How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?

Promotor: Prof.dr. G.R. de Snoo, Co-promotores: Dr. ing. M.G. Vijver, J.P.M. Vink

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Data science and statistics are closely linked, says Spinoza laureate and Stochastics professor Aad van der Vaart. We talk with him about the big data hype, genome research and collaboration with other disciplines. ‘Statistics helps wherever data is not perfect.’

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

PhD defence

Mechanical interactions between cells and their environment play an important role in many biological processes.

PhD defence

PhD defence

In the ‘Imaginary’ exhibition, its curators show how society is made up of mathematics. From algorithms that save lives to ones that generate art. The exhibition is from 2 June to 25 July at Oude UB in Leiden.

Do you have any questions about the master's specialisation Methodology and Statistics in Psychology? Please contact us.

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

This research project adresses the question how local and traditional European forms of parrhesiastic theater— events, actions, and performances staged by characters who courageously speak their minds through scenes of excess and laughter, that take place in public view and incite the spectator’s agency…

As of 1 November, Jan Vonk has been appointed full professor of Mathematics at the Mathematical Institute (MI). The institute is delighted with Jan’s appointment, as is he. ‘At the MI we combine the abstract with the concrete like no other.’

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

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The Leiden Institute of Advanced Computer Science (LIACS) of Leiden University proudly establishes the Blaise Pascal chair. The chair applies for one year and is meant to strengthen the cooperation of the Leiden computer science research with foreign institutes.

Missing legends, illogical connections or three-dimensional graphs. There are many ways in which data can deceive. Five students took up the fight against misleading statistics. Their lesson series can now be found online.

The Data-Driven Drug Discovery Network (D4N) is an initiative by researchers from Leiden University and collaborators to join efforts in applying and developing novel techniques from data science to drug discovery and related topics from bioinformatics.

Starting from September, the four Dutch mathematics clusters DIAMANT, NDNS, GQT and STAR will each be given 1 ME from NWO Exact Sciences, to be spent within a period of two years.