Can we link multiple components from herbal extracts with their biological activities?

Personalised healthcare could be the answer to insufficient treatment of chronically ill people. Therefore, PhD Junzeng Fu tries to predict the response of a patient to a drug. Strikingly, she combines western medicine with Chinese medicine diagnosis. Promotion Tuesday 21 February.

How such did the traditional text of the Sinews Transformation Classic remain interesting to a changing readership?

At Leiden University, researchers from all disciplines work together to find answers and design innovations in the field of artificial intelligence.

Andreas Bender, Assistant Professor for Medicinal Chemistry in the Medicinal Chemistry Division of the Leiden / Amsterdam Center for Drug Research, received the

Putting our interns to work’ is the third-year slogan for the Master’s Programme in Medicine at Leiden University. After their regular residency periods, students are encouraged to find an internship in demanding sectors where they would like to work after completing their studies. In the MasterMindsChallenge,…

Professor Thomas Hankemeier and his international research team HYPERMARKER have received a 10m-euro grant from Horizon Europe and UK Research and Innovation.

A new app provides dynamic predictions of survival for patients suffering from soft tissue sarcoma. It was developed by the mathematical Institute research group DASPO, Data Analysis and Survival for Personalised Oncology.

With a starting grant of the European Research Council (ERC) for promising young researchers, Eiko Fried aims to develop a personalised early warning system, that will reliably forecast depression before it occurs. Fried (Clinical Psychology) talks about this WARN-D, promising to radically transform…

What is the best method and time to test the effectiveness of medicines? PhD student Rob van Wijk of the Leiden Academic Centre for Drug Research (LACDR) discovered zebrafish larvae are best used in drug research when they are five days old. His findings were published on 15 February in the journal…

She has held office for over a hundred days, and is enthusiastic about what she has seen of the University thus far. Bursting with energy, she has plans aplenty for the teaching. An interview with ‘new’ Vice-Rector Magnificus of Leiden University, Hester Bijl.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

Not taking into account the saturation of drug targets can lead to wrong conclusions about the duration of a drug's action. This is what former PhD candidate Wilbert de Witte writes together with the Leiden professors of pharmacology Meindert Danhof, Piet van der Graaf, and Liesbeth de Lange in Nature…

The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.

Social science research helps us understand human behaviour and social structures. These are determined by various factors, which makes the research complex and increases the likelihood of drawing the wrong conclusions. The choice of research method and analysis is therefore extremely important. It…

The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…

The Metabolomics Facility of Leiden University is now officially in operation to prevent disease and to improve health throughout the human lifespan.

Mathematician Stéphanie van der Pas, winner of the C.J. Kok Jury Award for her PhD thesis in 2017, divides her time between research and education, and between pure mathematics and practical application.

Can the (industrial) herbal extraction process be mathematically described and can this model be used to optimize the extraction in terms of quality and economical parameters?

Promotor: Prof.dr. L.J. Slikkerveer

Science, Leiden Academic Centre for Drug Research (LACDR)

On Friday 17 April Leiden Mayor Henri Lenferink will officially open the new Metabolomics Facility of Leiden University. The facility’s ultimate goal is to prevent disease and to improve health throughout the human lifespan.

After 41 years, Meindert Danhof, Professor of Pharmacology, is leaving the Leiden Academic Centre for Drug Research on 31 March. A symposium in his honour, prior to his farewell lecture, will show what has been achieved in this period. Danhof takes a look back on his career.

Which plants are depicted, described or collected in these century-old objects? Who made these objects, where and for what purpose? What is their scientific and societal relevance today?

Seven new Medical Delta professors revealed their research plans in a lecture marathon on 21 June. The professors at Leiden University, the LUMC, Delft University of Technology and the Erasmus Medical Centre Rotterdam operate at the interface between life sciences and health and technology.

Operating on tsunami victims, coordinating emergency aid during a civil war and the croaking of frogs in the surgery: Menno Swier worked as a doctor of tropical medicine in Papua New Guinea and Indonesia. He is now a GP on Terschelling and here too there is never a dull moment.

We focus on natural products research, traditional medicine, ethnobotany and phytochemistry.

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

Funded by a ZonMw grant, the LUMC and the Health Campus The Hague will be working with headache patients on research into the use of an electronic headache diary. This resource can help patients gain a better understanding of their migraine attacks and, together with the physician, produce the best…

From 14 to 29 PhD candidates, seven actively involved faculties and, above all, lots of innovative interdisciplinary research, all with data science as the common denominator. The university’s Data Science Research Programme (DSO) has proven so successful that after five years on a start-up grant it…

Freek Janssen, a PhD-student in the department of Molecular Physiology, has received an award for the best oral presentation during the Young Medicinal Chemist Symposium organised by the European Federation of Medicinal Chemistry (EFMC-YMCS’16). Freek Janssen presented his work on “Development of Highly…

Laura Heitman is awarded the 2018 EFMC runner-up prize for a Young Medicinal Chemist in Academia

Spirits play a important role in post-colonial and minority literature as a means of processing black pages from history, according to literary scientist Chia-Sui Lee. PhD defence 11 January.

Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.

At the International Online Conference 'Fair Medicine and Artificial Intelligence' organised by the University of Tübingen (Germany), Hadassah Drukarch, junior researcher at eLaw, gave a presentation on how current algorithmic-based systems may reinforce biases in healthcare. This topic forms part of…

The Leiden Academic Centre for Drug Research (LACDR) received no less than three awards during the Figon Dutch Medicine Days. Bas Goulooze won the PhD Prize for best PhD candidate, Natalia Ortiz Zacarías and Huub Sijben both received a poster prize. ‘Scientists must be able to communicate their research…

Gerard van Westen and his group, together with pharmaceutical company Galapagos, start on developing software that invents new effective molecules. They will receive an NWO LIFT grant of 280,000 euros, of which 63,000 euros will come from Galapagos. The company will also bring its expertise in biology,…

Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…

,

Gerard van Westen and his group, together with pharmaceutical company Galapagos, start on developing software that invents new effective molecules. They will receive an NWO LIFT grant of 280,000 euros, of which 63,000 euros will come from Galapagos. The company will also bring its expertise in biology,…

Improving healthcare with our scientific discoveries: that is the goal of pharmaceutical research at Leiden University. And there’s a lot involved in that. Our research starts with the discovery of the effect achieved by a particular substance, and sometimes continues all the way through to the development…

The book ‘Geleerde Zorgen: twee eeuwen academische geneeskunde in Leiden’ (‘Learned Care: two centuries of academic medicine in Leiden’) was presented on 16 December to Annetje Ottow (President of the Executive Board of Leiden University) and Pancras Hogendoorn, Dean and member of the Executive Board…

Public funding for fundamental research is essential for innovation and the development of new medicines. This is demonstrated by Professor Science Based Business Simcha Jong and his colleague Hsini Huang after studying US federal funding restrictions for stem cell research under President George W.…

One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.