We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.

This project intends to provide the required knowledgebase for the design of novel mild intervention protocols to prevent fungal food spoilage.

What is the provenance of introduced populations?

Towards a Biological Understanding of the Middle to Upper Palaeolithic Transition

-

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

This research sets out to answer the following questions:

The aim of this PhD dissertation project is to study the effect of private foreign investment outside the realm of economics in the context of a colonial structure in Indonesia between c. 1910 and c. 1960.

This project aims at investigating the multidirectional effects of forced and voluntary forms of migration in the ancient Near East.

The nineteenth century truly was an age of transformation. Throughout Europe processes of industrialization and urbanization, nationalization and centralization, changed the structures of society. It was an age in which the number of people living in urban communities grew substantially.

The kidneys play a major role in the elimination of drugs. In children, the exact age-related physiological changes underlying kidney function remain largely unknown.

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

On the 1st of November, Andrew Wigman successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Andrew on this achievement!

The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Evolution & Biodiversity is one of the four research themes of the Institute of Biology Leiden.

This research investigates the impact of socioeconomic developments on the physical condition of medieval populations in Holland and Zeeland between AD 1000 and 1600 through the analysis of human skeletal remains from three archaeological sites.

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In this article, published on the website SAGE research methods, authors Jaroslaw Kantorowicz and Tobias M. Hlobil discuss how a Regression Discontinuity Design can be executed.

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

On the 6th of July, Anthony Jakob successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Anthony on this achievement!

PhD defence

PhD defence

PhD defence

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

Research in the POD-group addresses all features of random phenomena – modelling, structuring, analysis, control, optimisation – and covers both fundamental and applied aspects.

By comparing individual health data with population data, doctors can provide personalized health advice and patients can learn from each other's experiences. Wessel Kraaij, professor of Applied Data Analytics shows how personal data can have predictive value.

In this course, you will learn about sustainability and staying with the environmental boundaries of our planet. You will gain an understanding of the effects of growing affluence and population growth, the key challenges we are facing, and ways to influence your direct environment.

-

-

Our teaching is characterised by individual attention for students, contact with diverse cultures and innovative teaching methods. Personal supervision and the binding study advice contribute to our success. Our teaching and research are closely interwoven.

Chemistry is all around us: from nutrition and smartphones to medicine. The field is developing rapidly, as the world population continues to grow and resources become scarce. MST will educate you on the basics of working towards a clean and healthy world.

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

Dating back more than 400 years, Leiden University has the oldest continuous chair of Arabic outside the Arabic-speaking world. Today the MENA region is studied at Leiden from before the coming of Islam up to today from a wide array of disciplines. And Arabic is studied within the diverse linguistic,…

On 25 January 2024 H.J. Pak successfully defended a doctoral thesis and graduated.

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

Anthropogenic noise has been shown to affect marine animals in various ways, this may have fitness consequences at individual and population level. This thesis aims to increase insight into the quantification of sound-induced behavioural responses that are relevant to fitness, and into factors that…

In this book Adam Fairclough chronicles the odyssey of black teachers in the South from emancipation in 1865 to integration one hundred years later.

The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

.

This project develops methods for ensuring the anonymity of individuals in social network data.

Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.

The Encyclopedia of Global Human Migration provides a complete exploration of the prominent themes, events, and theoretical underpinnings of the movements of human populations from prehistory to the present day.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

In Uprooting the Diaspora, Sarah Cramsey explores how the Jewish citizens rooted in interwar Poland and Czechoslovakia became the ideal citizenry for a post–World War II Jewish state in the Middle East. She asks, how did new interpretations of Jewish belonging emerge and gain support amongst Jewish…

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.