617 search results for “prison system” in the Public website
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In vitro model systems for studying the impact of organic chemicals on the skin barrier lipids
This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.
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sentencing: a homicide case flow analysis of the Dutch criminal justice system
Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.
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for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Lessons from the Past for the Financial System of the Future
Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.
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System-level design for efficient execution of CNNs at the edge
A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.
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Measuring sustainability: an elaboration and application of the system of environmental-economic accounting for Indonesia
Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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A joint evaluation of local and systemic disease activity in treated-to- target rheumatoid arthritis
PhD defence
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Nanoparticle-based combination drug delivery systems for effective cancer treatment
PhD defence
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Myfel Paluga
Faculteit der Sociale Wetenschappen
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Prof. Ton Liefaard member of Council for the Administration of Criminal Justice and Protection of Juveniles
Prof. Ton Liefaard has been appointed as member of the Council for the Administration of Criminal Justice and Protection of Juveniles.
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Revealing the origins of solar systems: examining the formation of proto-planetary disks and binary stars
What is the origin of solar systems?
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and Cosmetic (MAC) Plants in the Utilisation of the Plural Medical System in Pirgos and Praitoria for Community Health Development in Rural Crete
Promotor: Prof.dr. L.J. Slikkerveer
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The phonological systems of the Mbam languages of Cameroon with a focus on vowels and vowel harmony
The languages of the Mbam-et-Inoubou District of the Centre Region of Cameroon have a unique position in Bantu linguistics. Being in between
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Scientific understanding and provision of an enhanced and robust monitoring system for Responsible Research & Innovation (RRI)
Across Europe, the need for a more dynamic governance and a better societal integration of research and innovation is increasingly appreciated. Internal drivers of change (such as the digitalization of science) and political will to better align with societal needs and concerns are bringing about aspirational…
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self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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Institute of Criminal Law and Criminology
Everyone most obey the law. If you don’t, you will face the police and the courts. The application of national, European and international criminal law would seem to be a matter of following the letter of the law. But the reality is more nuanced. Criminal law scholars and criminologists from very different…
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the study of physics: An investigation of physics teachers' belief systems about teaching and learning physics
This doctoral thesis comprises four studies on the content and structure of physics teachers’ belief systems about teaching and learning physics in secondary education in the Netherlands.
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Handbook of Signal Processing Systems
Handbook of Signal Processing Systems is organized in four parts. The first part motivates representative applications that drive and apply state-of-the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these applications;…
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engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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tanks in a consensus – seeking and neo-corporatist policy advisory system
Bert Fraussen and Valérie Pattyn theoretically contribute to the existing literature on policy advice by drawing inspiration from niche theory.
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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The intergenerational transmission of an extreme belief systems: Theoretical exploration of a new field of study
With the recent rise and fall of IS, academics and policy makers around the world are expressing concerns about the fate of children of former foreign fighters. Will they follow in their parents’ footsteps? In this paper, Layla van Wieringen, Daan Weggemans and Marieke Liem argue that in light of this…
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Material flow analysis for the C&D waste management systems in the Netherlands, Belgium, Spain and Finland
What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…
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Arrest, detention and release of jihadists
People who are arrested on suspicion of preparing an attack are at risk of becoming radicalised either during or after their detention. Whether or not to arrest someone requires careful consideration. At the end of the prison sentence, it is important to provide effective supervision of the reintegration…
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer
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β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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The spin evolution of accreting and radio pulsars in binary systems
Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.
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More than a digital system: how AI is changing the role of bureaucrats in different organizational contexts
In this paper, Sarah Giest and Bram Klievink highlight the effects of AI implementation on public sector innovation. This is explored by asking how AI-driven technologies in public decision-making in different organizational contexts impacts innovation in the role definition of bureaucrats.
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Joni Reef at opening Expertise Centre KIND
Joni Reef was among those present at the opening of Expertise Centre KIND in 's-Hertogenbosch on Thursday 22 November 2018. She spoke to Dutch newspaper Brabants Dagblad afterwards.
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modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Reintegrating delinquents with an extremist background: evaluation of the Dutch approach
How to minimalize the chance of recidivism for extremist prisoners.
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Pharmacometabolomics; prediction of system-wide multi-biomarker drug response
The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.
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Shielding software systems: A comparison of security by design and privacy by design based on a systematic literature review
The authors systematically search and review relevant definitions of Security by Design (SbD) in comparison with Privacy by Design (PbD).
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Berent Baris
Science
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José Mogollón
Science
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Willem Meilink
Science
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Xinpeng Jin
Science
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Anke van der Hoeven
Faculteit Rechtsgeleerdheid
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Roosje Peeters
Faculty of Humanities
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Arko Ghosh
Faculteit der Sociale Wetenschappen
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The immune system: step it up or slow it down?
When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…
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The Subjectively Experienced Severity of Imprisonment
On Thursday 12 January 2017, Ellen Raaijmakers defended her doctoral thesis ‘The Subjectively Experienced Severity of Imprisonment: Determinants and Consequences’. The defence took place at the Academy Building of Leiden University, Rapenburg 73. The PhD research was supervised by Professor P. Nieuwbeerta…
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Louwerse, ‘The predictive value of polls in a fragmented multi-party system’
Political scientists Tom van der Meer, Lisa Janssen (University of Amsterdam) and Tom Louwerse (Leiden University) analyse polls presented by the main polling agencies in the Netherlands, as well as micro-level panel data. They reach three main conclusions. First, vote intention polls in the Netherlands…