984 search results for “safety” in the Public website
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Utopia: Universal Three-dimensiOnal Passport for process Individualization in Agriculture
Agricultural foods naturally vary in their detailed internal structure. To facilitate early detection of health hazards due to contamination or disease, predict maturity and minimize wastage, it is critical to take into account the internal characteristics of each individual product, as these enable…
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What is the effect of long-term exposure to engineered nanomaterials (ENMS)?
Engineered nanomaterials (ENMs) are widely used, and nanotechnological innovations grow with rapid pace. Studies on nanotoxicology have demonstrated that chemical toxicology as well as particle toxicology should be accounted for in predicting the safety of ENMs.
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Public service professionals coping with contrasting demands
Double Bind. Public service professionals coping with contrasting demands. How do public service professionals align their PSM with contrasting demands set by the organizational and social contexts in which they work?
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Master's application and admission
Find out how to apply for Drug Discovery and Safety at Leiden University by following our step-by-step guide.
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Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
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Life after Security Studies: five alumni share their thoughts about the bachelor programme
Five students who graduated from the Bachelor Security Studies share their experiences. Where did they end up after graduation? Are they still using the skills they gained during their studies?
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Bart Schuurman receives Veni Grant: Who do not become terrorists?
Bart Schuurman, Assistant Professor at the Institute of Security and Global Affairs in The Hague, has received a Veni grant which will allow him to continue his research into the radicalisation of terrorists for the next three years. ‘In order to better understand terrorists, I will focus on the large…
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4D measures of migration as safety prediction of hip and knee implants
PhD defence
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Programme structure
The strengths of this master’s specialisation are its research-orientated approach, combined with training in safety and quality control in the production of medicinal products in the biotechnology and pharmaceutical industry.
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Terrorism and Political Violence
Understanding the evolving landscape of extremism in the 21st century.
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Intracellular allosteric modulators for human CC chemokine receptors
Supervisor: Natalia Ortiz Zacarías
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XAIPRE - Explainable AI For Predictive Maintenance
The project XAIPre (pronounce “Xyper”) aims to develop predictive maintenance system for the maritime industry using sensor technology and artificial intelligence. The project aims at developing Explainable Predictive Maintenance (XPdM) algorithms that do not only provide the engineers with a prediction…
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Scientific integrity
All LIAS members and visitors are kindly requested to familiarize themselves with the information provided below, to the level of detail they feel is appropriate to their situation. This information overlaps in part with the University’s web pages on scientific integrity.
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High-throughput screening for developmental and reproductive toxicity
Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?
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Mathematical modelling of adverse outcome pathways
In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.
- Facilities and services
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Bio-Pharmaceutical Sciences (MSc)
The master’s programme of Bio-Pharmaceutical Sciences at Leiden University examines the research area of bio-pharmaceutical sciences and drug research. It offers seven specialisations ranging from BioTherapeutics to Industrial Pharmacy.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Programme structure
Throughout your 3-year Security Studies programme you explore the effects of events (such as war or natural disaster), understand them via relevant academic perspectives, and actively design strategies and solutions to resulting security challenges.
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Research
The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Drug Discovery & Safety and Systems Biomedicine and Pharmacology, and the Metabolomics and Analytics Centre.
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Leiden Academic Centre for Drug Research
The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.
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Education
Social Policy is increasingly incorporated as a subject of European law. The Social Dialogue with labour and management organisations leads to agreements that can be transformed into Directives of the Council
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System-level design for efficient execution of CNNs at the edge
A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.
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The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries)
The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries) investigates the development of General Average and other so-called Averages in the Low Countries on the eve of the early modern period, showing how the various varieties…
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Leiden’s City Criminologist
How safe do you feel when you’re walking around the streets of Leiden? Do you generally feel safe? Are there any situations when you feel unsafe in the city? These are the kinds of questions that Leiden’s City Criminologist Marianne Franken – from Leiden University – hopes to be able to answer. In collaboration…
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Weekly Lectures
As a part of NVIC's film & lecture program, you can join a public film screening on Sundays at 7 pm, and a lecture on Thursdays at 6 pm. Seats are limited and we work on a first-come, first-serve basis. Our doors open 30 minutes in advance, and close 15 minutes after starting time or earlier in case…
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Administration and Central Services and Expertise Centres
The Administration and Central Services department supports the Executive Board and is responsible for policy and decision-making.
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Characterization of Cell-based medicinal products (CBMPs)
Cell-based medicinal products (CBMPs) show great promise when it comes to the treatment of genetic disorders. However, there is limited knowledge about CBMP stability during their production, storage, and administration to patients. The main focus of my research is the characterization of CBMPs using…
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Biorythm and brain dysfunction
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Dividing Worlds
Dividing Worlds: Tsunamis, Seawalls, and Ontological Politics in Northeast Japan
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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VOILA (Validation of Innovative Lipopeptide Antibiotics)
Examining the therapeutic potential of new semisynthetic lipopeptide antibiotics
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Quantitative Clinical Pharmacology
The Quantitative Clinical Pharmacology group is led by Prof. Dr. Catherijne Knibbe. Her research group aims to define how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically ill patients. Through combining the statistical…
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Population PKPD analysis within the “DINO-Trial” evaluating the pharmacokinetics and pharmacodynamics of routinely used off-label drugs in premature
Currently, more than 80% of drugs are used in an off-label manner in critically ill neonates.
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People
The Cell Observatory is run by several people some of which have multiple roles. To identify whom to contact for what issue please refer to the list below
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Babylab Leiden
Babies learn their native language(s) amazingly quickly, and they know a lot about how people behave and about properties of objects from a very young age. The researchers of the Babylab at Leiden University are trying to understand how these skills develop.
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Systems pharmacology-based translational drug pharmacokinetics
High-throughput holistic preclinical screens are increasingly used in drug discovery, to assess both drug efficacy and drug safety.
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Why do we use laboratory animals?
We use laboratory animals to address research questions, but only when there is no alternative and the question cannot be answered in any other way. Read here why we conduct animals experiments.
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Strategy
The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.
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Ruling: temporary coffeeshop licences are allowed
Coffeeshop licences may be issued temporarily and reissued after this period has expired. This follows from a ruling by the Administrative Jurisdiction Division of the Council of State in the appeal lodged by the mayor of Roermond municipality against the Court's April 2021 ruling.
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Keyring in your hand when walking down the street alone? 'Many women are always on guard'
A cover over your drink in the pub, deodorant as pepper spray or headphones to avoid hearing catcalling: many women use everyday objects to feel safer in public spaces. Student Anne van der Linden made an online exhibition about this.
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Marieke Liem on juvenile delinquents
A juvenile suspect has been apprehended for the murder of 15-year old Megan from Breda last Monday. A highly unusual situation, according to Marieke Liem, Associate Professor at the Institute of Security and Global Affairs in The Hague. She gave an interview to Dutch newspaper AD.
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Jelle van Buuren about the criminal trial of Gökmen Tanis from the tram attack in Utrecht
On 18 March 2019, Gökmen Tanis shot three people in a tram in Utrecht. He shot a fourth victim after exiting the tram on the 24 Oktoberplein. On 1 July, the criminal trial against Tanis started with presumably only one possible outcome: a life sentence.
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Study and working conditions
Make sure you have a suitable place to work or study at home.
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Occupational health in the Emergency Department: A study on work-related factors and health/well-being in nurses and doctors in 19 Emergency
Occupational health in the Emergency Department
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Our team
Researchers from five different discplines work together in this interdisciplinary initiative.