660 search results for “safety” in the Public website
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Organisation
Organisation of the Leiden Institute of Physics.
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A large-scale crop protection bioassay data set
ChEMBL is a large-scale drug discovery database containing bioactivity information primarily extracted from scientific literature.
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Animal models for cutaneous vaccine delivery
Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.
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Combatting infectious diseases; nanotechnology as a platform for rational vaccine design
Currently, several successful vaccines are available. However, for pathogens with a highly variable genetic composition, and for which serum IgG antibodies are not a useful correlate of protection, effective vaccines are yet to be developed.
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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Drug research
In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.
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Strategic Interaction of Governments and Terrorist Groups in Times of Economic Hardship
In this article, Tokdemir & Klein examine the strategic actions of governments against domestic terrorist groups and domestic terrorist groups’ reactions to such actions.
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Jimpitan in Wonosobo, Central Java: an indigenous institution in the context of sustainable socio-economic development in Indonesia
In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.
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Optimization of Patient Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
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Spectral imaging and tomographic reconstruction methods for industrial applications
Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.
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Teris van Beek
Dr. at the Department of organic chemistry, Wageningen University - the Nederlands
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Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Chemical Similarity: Structuring Risk and Hazard Assessment
At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.
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Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
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Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
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Study programme
The PML specialisation prepares you with knowledge and understanding of the key concepts and theories of management, leadership, decision-making and policy implementation in national and international government organizations.
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Career prospects
After graduation you have a lot of opportunities: academics are highly sought after in Dutch secondary education or mbo teaching. You can also aim for a management position or work as a researcher within the field of Life Sciences.
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Walkout on 13 May
A national walkout will be staged on Monday 13 May. Leiden Scholars for Palestine has called on students and staff from Leiden University to meet at 11.00 at the Lipsius building in Leiden and the Wijnhaven building in The Hague.
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Information for organisations
The Leiden Leadership Programme of Leiden University maintains partnerships with roughly 40 organizations, companies, and governments. Students tackle leadership issues within these organisations.
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Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
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Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
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To what extent are face coverings permitted at demonstrations?
Recently, the University of Amsterdam was the scene of pro-Palestinian demonstrations that got out of hand. The demonstrators included rioters who wished to remain anonymous by wearing face coverings. Several experts, including Wim Voermans, Professor of Constitutional and Administrative Law, spoke…
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Maartje van der Woude
Faculteit Rechtsgeleerdheid
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Admission requirements
To be eligible for MSc Crisis and Security Management at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for MSc Crisis and Security Management at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for MSc Crisis and Security Management at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for MSc Crisis and Security Management at Leiden University, you must meet the following admission requirements.
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BSc Security Studies
On this page you will find all information about the Bachelor of Security Studies that you need as a first-year student.
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Leiden University starts dismissal procedure against professor on the grounds of unacceptable behaviour
A professor from Leiden University, together with a former employee (who is also the professor’s partner), has been guilty of long-term unacceptable and often transgressive behaviour in the form of abuse of power and manipulation. This behaviour led to a culture of fear among staff who were largely…
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Essays on wealth, health, and data collection
On 21 November 2018, Lieke Kools defended her thesis 'Essays on wealth, health, and data collection'. The doctoral research was supervised by Prof. dr. K.P. Goudswaard en Prof. dr. C.L.J. Caminada.
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Facts and figures
We are transparent about our research involving laboratory animals, which includes providing access to our annual statistics. On this page, you will find an overview of various aspects, such as the number of animals and the species we use, the types of research for which we employ animals, and the level…
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Diplomacy at Leiden University
The Hague Journal of Diplomacy is hosted by the Institute of Security and Global Affairs at Leiden University. Besides the journal, there are many other activities related to diplomacy.
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Multi-objective Evolutionary Algorithms for Optimal Scheduling
Multi-objective optimization is an effective technique for finding optimal solutions that balance several conflicting objectives. It has been applied in many fields of our world, because practical problems usually have more than one desired goal. For example, developing a new vehicle component might…
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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SCALES project
How to strike a balance between the sometimes conflicting stakes of individual, public and private data-producers and data-processors?
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Discoveries in 2023
From nanoparticles to colliding ice planets and from biological origami to new x-ray scanner techniques: this year again, our scientists have made wonderful discoveries. From the largest numbers to the smallest molecules and from the oldest galaxies up to the latest algorithms, take a look at each institute's…
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Development of Cost efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
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Host community compensation
Can the offering of host community compensation help to prevent or solve siting controversies, and if so, why and under which conditions?
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Gendered impacts of industrial logging
This study focuses on the local level impacts of a highly globalised industry: the international trade in tropical timber.
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Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems
On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.
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Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Focal Areas
Our research at CWTS is organized in three focal areas. These focal areas represent our core areas of interest, as defined in our knowledge agenda for the period 2023-2028.
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Prediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling
Source: J Cheminform, Volume 7, Issue 1 (2015)
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.