Data science is of vital importance in preventing future outbreaks of viruses, Professor of Data Science Aske Plaat argues. Inaugural lecture entitled ‘Data Science and Ebola’ on 13 April.

Today, everybody and everything produces data. People produce large amounts of data in social networks and in commercial transactions. Medical, corporate, and government databases continue to grow. Sensors continue to get cheaper and are increasingly connected, creating an Internet of Things, and generating…

In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…

The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.

The genetic code of the new coronavirus has been found: it is closely related to the SARS virus from 2003. Professor of Molecular Virology, Eric Snijder, has been researching coronaviruses for years. We asked him a few questions about the outbreak. ‘It’s still unclear whether this new virus is more…

Following current regulations regarding the attempts to constrain the effects of the Corona virus outbreak, the University of Leiden has cancelled all physical forms of teaching until 6 April. As conference organisers, we will use this period to consider how to proceed with the conference. In the most…

VODAN Africa started as a platform to enable access to critical data needed from Africa to fight the novel COVID-19. The initiative was inspired by the experience from the Liberia Ebola Virus outbreak in 2014: early detection requires contact tracing. Inclusion of the most vulnerable is critical to…

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

Physicists, including Leiden researcher, Sanli Faes, have devised a new technique for studying processes at microscale rapidly and extremely precisely. This new method will make it easier to develop antiviral medication. And it doesn’t stop there. Publication in ACS Nano.

Although Ebola is a virus with significant fatality rates, we still lack effective countermeasures to battle it. To change this, Alireza Mashaghi and his colleagues from the Leiden Academic Centre for Drug Research have successfully developed an organ-on-a-chip model that imitates the most dangerous…

Many dangerous diseases such as COVID-19, Ebola and Q fever have jumped from animals to humans. But it is not only because of these diseases that we should include animals in our health policy, but also because of their right to health, writes PhD candidate Joachim Nieuwland. PhD defence on 13 May.

If you'll soon be getting a COVID-19 vaccine, you might just get the Johnson & Johnson (Janssen) one. This vaccine was developed for the most part in Leiden – and this is no coincidence. Watch the animation below about the development of one of the vaccines in the fight against COVID-19.

The European PANVIPREP research project started at the Leiden University Medical Center on 11 March. The participants are virologists, biochemists and pharmacists from 14 European countries. Their mission is to develop antiviral drugs to protect Europe during pandemics. At least two such antivirals…

A COVID-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies is shown to provide good protection in a mouse model, Leiden University Medical Center (LUMC) researchers report in Nature Communications. According to them, the alternative vaccine may offer a…

Leiden University is awarding an honorary doctorate to virologist Marc van Ranst. Van Ranst has been one of the main advisers of the Belgian government during the Covid pandemic. German Arabist Beatrice Gründler will also receive an honorary doctorate for her work in the field of Oriental Manuscript…

Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research in the group of Ton Schumacher (Dutch Cancer Institute, NKI) and computer simulations in collaboration with Rob…

Due to the by now world-wide Covid19 restrictions on travelling and holding meetings, the committee has decided to cancel the conference in June. We are now looking into postponing the conference (either to a later date in 2020 or to 2021). We will keep you informed about any further developments. All…

Assistant Professor Christopher Green was interviewed on ABC Australia about the recent COVID-19 outbreak in North Korea. Green says that the statistics the isolated country has given are ‘essentially nonsense’.

What Accounts for the Variety of National Policy Responses to the COVID-19 Pandemic in Europe?

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

All acute care staff at Leiden University Medical Center have received their first and sometimes even their second dose of the coronavirus vaccine. But how long will you be protected after vaccination and what does the genetic material of the virus do in the vaccine? Our virologists Ann Vossen and Leo…

Moritz Jesse, Associate Professor at the Europa Institute Leiden, was a speaker at the International Conference European Constitutionalism And the Virus of Distrust Conference, which took place on 27 and 28 April in Prague. The Conference brought together academics from all over the European Union to…

Understandably, coronavirus is often viewed from a medical perspective. However, researchers in the social sciences and humanities possess a great deal of expertise that could improve our understanding of the virus outbreak and its impact on society. A new portal is consolidating this knowledge.

Gathering and distributing patient data can make an important contribution to containing the coronavirus. But if we want to be successful, we need better data. With this objective in mind, Leiden data stewards have joined the Virus Outbreak Data Network (VODAN).

Professor of Ecotoxicology Martina Vijver had planned an eight-week field work course for her students, but the corona virus threw a spanner in the works and Vijver had to come up with a new plan at short notice. ‘Without the help of my own network and that of my colleagues this would have been very…

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…

Epithelial cells play a crucial role in the lungs. PhD student Ying Wang researched the effects of cigarette smoke and viruses such as COVID-19 on these epithelial cells. ‘We hope to reduce the risk of pandemics in the future.’

How can the Netherlands be better prepared for infectious diseases transmitted by mosquitoes. The Dutch Research Council (NWO) has awarded almost 9 million euros for this research. Maarten Schrama from the Institute of Environmental Sciences CML coordinates the input of Leiden University within the…

Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…

Knowing how to resolve global problems is one thing, but how do you make sure that it actually happens? That’s the real challenge, because there are powerful movements everywhere that want to reconstruct the walls of nation states. In an attempt to resolve this issue, Leiden researchers are experimenting…

Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…

An overview of awards and prizes granted to our staff and students in 2019, as well as special appointments and royal distinctions.

The Open Day of Leiden University, on the 8th of this month, was a success again: 483 prospective students came to find out what Leiden has to offer. The Institute of Biology Leiden was also present.

The potential of bioneedles to deliver influenza vaccines was investigated.

A team of students from Leiden won the iGEM international biology contest in 2020 with their Rapidemic mobile testing kit. The kit makes it easy to detect viruses. The team has now been nominated for the Most Innovative Student in the Netherlands prize. Cast your vote and help them develop their inv…

Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a grant from the Elise Mathilde Fund and the LUF to develop innovative phage-antibiotic combination treatment strategy for combating AMR.

The people behind the Leiden University Libraries aim to maintain the level of their services to clients as much as possible. They are making thankful use of internet, but not everything can be put online.

Fake news about ‘patient zero’ and hyperbolic headlines warning about the ‘yellow peril.’ Leiden researchers have spotted fake news galore about coronavirus as well as racial stereotypes about the Chinese. How harmful is this?

It’s all hands on deck at the moment to resolve the COVID-19 crisis. Researchers from various disciplines are helping where they can, also from the field of artificial intelligence (AI). AI offers great opportunities both at the frontline of the crisis and in its expected aftermath. Leiden professor…

Why have some European countries responded faster to the coronavirus outbreak than others? While in some countries the lockdown had already been declared when relatively few cases were known, others did not take action until thousands of people were already infected and hundreds were already dead. What…

The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…

The Dutch National Research Agenda announced today that it will provide 17 research projects with a total of 61 million euros in funding. Researchers from Leiden University or the Leiden University Medical Center are involved in five of the projects. All of the projects are interdisciplinary partnerships…

Decision makers are faced with dilemmas as result of the corona crisis. Dr. Jeroen Wolbers, Assistant Professor Crisis Governance at the Crisis Research Center explains the existing dilemmas and what makes the corona crisis unique when compared to other crises.

Fourteen bachelor’s and master’s students are representing Leiden University in this year’s International Genetically Engineered Machine competition (iGEM). Their plan: to create a kit that can be used to quickly identify infectious diseases in case of an outbreak.

In a joint letter, the Leiden student associations have appeal to students to practise 1.5m distancing and to only meet others if they are fit and well. They urge them to observe the corona rules to prevent a local spike.

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

What are 'defects' and mechanical properties of mosaics of different shapes of tiles?

The Viral Vector Facility produces batches of lentivirus and adenovirus for preclinical research within the LUMC. And it assists researchers to produce their own virus.

Scientists at the LUMC are working hard on potential virus inhibitors, antiviral screening and a treatment for COVID-19. SteunLeiden.nl has started a crowdfunding campaign for this research, under the hashtag #wakeuptocorona. Professor of Virology Eric Snijder explains why this is desperately needed…