The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Understanding DNA repair mechanisms is essential for advancing plant biotechnology and crop improvement. This study investigates how double-strand breaks (DSBs), induced by CRISPR/Cas systems, are repaired in the model plant Arabidopsis thaliana, and how these processes influence Agrobacterium tumefaciens…

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Het onderzoeksprogramma Probability Theory richt zich op kansrekening en op operationeel onderzoek.

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Promotor: H.W. Lenstra, Jr., Co-promotor: B. de Smit

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

This dissertation is a collection of four research articles devoted to the study of Kummer theory for commutative algebraic groups.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

In analogy to mathematical proofs, the goal of a proof system is for a prover to convince a verifier of the correctness of a claim.

In this thesis we examine certain phenomena in symplectic topology which are related to the theory of isolated singularities.

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

Het onderzoek binnen het Algebra, Geometry and Number Theory programma varieert van fundamentele wiskundige theorie tot algoritmes en toepassingen.

To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.

In de masterspecialisatie Algebra, Geometry and Number Theory verbreed je je kennis van de zuivere wiskunde met onderwerpen als getaltheorie, algebraïsche meetkunde, algebraïsche topologie en cryptologie.

The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.

De masteropleiding Cultural Analysis: Literature and Theory van de Universiteit Leiden richt zich op de studie van literatuur vanuit een vergelijkend en theoretisch perspectief, en onderzoekt de literatuur van een breed spectrum van talen en culturen uit de hele wereld.

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

This six-weeks online course delves into the research behind terrorism as it unpacks the assumptions and impacts of both terrorism and counterterrorism.

Ontdek de MSc Political Theory: Legitimacy and Justice aan Universiteit Leiden — verdiep je in rechtvaardigheid en legitimiteit, bestudeer klassieke en moderne politieke filosofie en ontwikkel je analytische en filosofische vaardigheden.

Lees meer over de voorlichtingsactiviteiten rond de MSc Political Theory: Legitimacy and Justice aan Universiteit Leiden, zoals webinars, virtuele open dagen, Q&A-sessies en evenementen voor toekomstige studenten.

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

Promotor: J. Zaanen

Bekijk de opbouw van de MSc Political Theory: Legitimiteit en Rechtvaardigheid aan Universiteit Leiden: kernvakken, keuzevakken, methodenvakken, scriptie of stage, en kleinschalige seminars.

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Heb je een vraag over het studentenleven in Leiden en Den Haag, studeren aan de Universiteit Leiden of wil je meer informatie over de masteropleiding Political Science? Neem dan direct contact op met een student van deze opleiding!

Effective policy-making requires understanding what truly causes a problem. Only then can policymakers develop targeted interventions that achieve desired outcomes.

Promotor: Prof.dr. G.P. van Wezel

Ontdek het studentenleven bij de MSc Political Theory: Legitimiteit en Rechtvaardigheid aan Universiteit Leiden: studieverenigingen, activiteiten, academische gemeenschap en wonen in Leiden en Den Haag.

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Ontdek de MSc Political Theory: Legitimiteit en Rechtvaardigheid aan Universiteit Leiden — met focus op politieke filosofie, diepgaande theorievakken, keuzevakken, en afsluiting met scriptie of stage.

Bekijk de toelatingseisen voor de MSc Political Theory: Legitimacy and Justice aan Universiteit Leiden — bachelordiploma in (of verwant aan) Politicologie met voldoende relevante studiepunten en, indien nodig, methodologische achtergrond.

Bekijk informatie over het collegegeld voor de master Political Theory: Legitimacy and Justice aan Universiteit Leiden, inclusief hoe tarieven verschillen per nationaliteit, kwalificaties en type programma.

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

Ontdek de extra uitdagingen bij de MSc Political Theory: Legitimacy and Justice aan Universiteit Leiden — zoals de Honours Academy, leadershiptrainingen en extra onderzoeks- of verdiepingstrajecten.

Ontdek waarom Universiteit Leiden dé plek is voor de MSc Political Theory: Legitimiteit en Rechtvaardigheid — met toponderwijs in politieke filosofie, kleinschalige seminars en deskundige docenten.

Lees hoe je je kunt aanmelden voor de MSc Political Theory: Legitimiteit en Rechtvaardigheid aan Universiteit Leiden met stapsgewijze aanmeldinstructies, documenten via Studielink en vervolgstappen na inschrijving.

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

Bekijk de aanmelddeadlines voor de MSc Political Theory: Legitimacy and Justice aan Universiteit Leiden — met aparte datums voor visa/verblijfsvergunning en voor studenten zonder visumplicht voor september en februari.