Promotor: Prof.dr. E. Deprettere

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

Promotor: P.M. Brakefield

Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen

This thesis focuses on addressing four research problems in designing embedded streaming systems.

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

Hoe kunnen docenten de gespreksvaardigheid in MVT van de individuele leerling in klassen van 30 verbeteren?

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Promotor: B. van de Water

In this dissertation several settings in the Online Learning framework are studied. The first chapter serves as an introduction to the relevant settings in Online Learning and in the subsequent chapters new results and insights are given for both full-information and bandit information settings.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.

This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Promotor: B. van de Water

In the era of big data, extracting insights from complex datasets is a key challenge. This thesis demonstrates the superiority of graph-based methods over traditional clustering (e.g., k-means, DBSCAN) and outlier detection for analyzing high-dimensional and noisy data.

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

Lezing

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Promotores: J. Jonkers, K.E. de Visser

This thesis investigates Open-world Continual Learning (OWCL), a learning paradigm designed for intelligent systems operating in non-stationary environments with persistent exposure to unknown data.

In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

Studieondersteuning, Loopbaanontwikkeling, Communicatie, Persoonlijke ontwikkeling

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.

Bij het Leiden Leadership Programme zijn experts op het gebied van leiderschap werkzaam. Zij rusten de LLP-studenten toe met de nodige kennis, inzichten en vaardigheden op het gebied van leiderschap om zo hun maatschappelijke impact te vergroten.

Dit blijkt uit het onderzoek ‘The Class Divide in Urban Indian Youths’ Lives; Their Time-Use and Adaptive Functioning’ van Radhika Bapat.

Het onderzoeksproject van Prof.Dr. Arjen Doelman ‘Adaptive Semi-Strong Ecosystem Dynamics’ is geselecteerd voor financiering als een van de 7 onderzoeksprojecten binnen het programma Mathematics of Planet Earth (MPE) van NWO.

Electives bieden studenten de mogelijkheid om zich verder te specialiseren en verdiepen in specifieke aspecten van leiderschap.

Astronomen willen het heelal begrijpen, van de Oerknal tot nu, en hoe dit verder zal gaan. In Leiden concentreren ze zich daarbij op twee vragen: 'Hoe ontstaan sterren en planeten? en 'Hoe ontstonden in het jonge heelal sterrenstelsels en zwarte gaten?' Een nieuwe generatie telescopen – net klaar of…

Groeiende gezondheidsverschillen, toenemende zorgkosten, de vergrijzing en het tekort aan zorgpersoneel zijn slechts enkele voorbeelden van uitdagingen waar de gezondheidszorg voor staat, zowel in Nederland als daarbuiten. Deze vraagstukken overstijgen de grenzen van de medische sector en raken aan…

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

Cognitief psycholoog prof.dr. Bernhard Hommel is gekozen tot lid van de Leopoldina, de Deutsche Akademie der Wissenschaften. Het lidmaatschap van de Leopoldina is een blijk van internationale erkenning.

Terug de collegebanken in om samen met masterstudenten colleges te volgen: dat deden professionals de afgelopen tijd bij het Leiden Leadership Programme. Na afloop van het experiment blijkt: leren over leiderschap smaakt naar meer. ‘Geweldig dat dit kan.’

Paul Brakefield, hoogleraar evolutiebiologie van het Instituut Biologie Leiden (IBL), heeft een ERC Advanced Grant ontvangen voor zijn onderzoek. Hij krijgt 2,5 miljoen euro om in een periode van vijf jaar zijn onderzoeksprogramma verder uit te bouwen.

Stimulerende drugs als khat en cocaïne hebben negatieve impact op dagelijkse handelingen als autorijden, werk of sociaal gedrag. Dat komt door beschadiging van controlefuncties in de hersenen. Psycholoog Manuel Ruiz draagt bij aan beter begrip en behandeling van drugsmisbruik. De Spanjaard Ruiz promoveert…

De jaarlijkse Oortlezing, ter herinnering aan de befaamde Nederlandse sterrenkundige, wordt georganiseerd door de Stichting Het Jan Hendrik Oort Fonds en de Sterrewacht Leiden. De lezing belicht een actueel sterrenkundig onderwerp en is bedoeld voor een breed publiek met interesse in de astronomie.…