134 zoekresultaten voor “chronic kidney failure” in de Publieke website
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Pharmacist-driven interventions in patients with chronic kidney disease and end-stage renal failure
Promotie
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Studies on the Pathogenesis of Chronic Kidney Disease
In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…
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Identification of genetic determinants of kidney function and chronic kidney disease
Promotie
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Chronic and end-stage kidney disease in Indonesia
Promotie
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Acute and chronic pain after cardiac surgery
Promotores: C.A.J. Knibbe, D. Tibboel, Co-Promotor: P. Bruins
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Online Course Clinical Kidney, Pancreas and Islet Transplantation
Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Celtypes in kaart gebracht van foetale nier
Nierfalen is een serieus probleem omdat nieren zichzelf niet kunnen regenereren na ernstige beschadiging. Een mogelijke oplossing bestaat uit het kunstmatig laten groeien van gezond nierweefsel. Daarvoor moeten wetenschappers eerst de ontwikkeling begrijpen tijdens de allereerste fase, in de foetus.…
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Making Sense of Business Failure
Op 1 juli 2020 verdedigde Niek Strohmaier zijn proefschrift 'Making Sense of Business Failure'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.A.A. Adriaanse en dr. H. Pluut.
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mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Steps toward pre-clinical iPSC-derived Kidney Organoids
Promotie
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Beyond the Binary: A New Typology for Evaluating Warning Success and Failure in Strategic Surprise
Dr. Nikki Ikani daagt de binaire visies op inlichtingenwaarschuwingen uit en stelt een typologie voor om de effectiviteit van waarschuwingen te evalueren.
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models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Jennifer BeckerFaculteit der Sociale Wetenschappen
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Unraveling the drivers of antimicrobial pharmacokinetic variability in individuals with obesity and hospitalized patients with multimorbidity
Obesity may alter how a person absorbs, distributes, metabolizes or excretes medication. This thesis describes how obesity affects drug levels in the blood for antimicrobial agents, such as ciprofloxacin and fluconazole.
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Clinical and patient reported outcomes in chronic kidney disease
Promotie
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Appropriate care for older people approaching kidney failure
Promotie
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Navigating the future with chronic kidney disease. Towards patient- centred prognostic modelling in nephrology
Promotie
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Sofie RasmussenFaculteit der Wiskunde en Natuurwetenschappen
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Exposed to events that never happen: Genaralized unsafety and prolonged psysiological stress responses
The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.
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Exploring kidney organoid vascularization
Promotie
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Tim VerdoesFaculteit der Rechtsgeleerdheid
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Marlies Reinders
Integratie van MOOC in campus
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Peter van der ZwanFaculteit der Rechtsgeleerdheid
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Balancing Immunogenicity and Histocompatibility in Kidney Transplantationc
Promotie
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Does it still hurt?
The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.
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Business incubators: the impact of their support
A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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Innovative diagnostics and treatments
Hoe meer we leren over een (neuro-)psychologische of lichamelijke aandoening en de hieraan gerelateerde gedragsfactoren, hoe beter we deze niet alleen kunnen signaleren, maar ook behandelen. Het is dus belangrijk dat recente inzichten over (neuro-)psychologische problemen en daaraan gerelateerde gedragsfactoren…
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Online Course EU Policy & Implementation: Making Europe Work!
In this top-rated course, you will learn how the European Union prepares and decides on policy, and how policy is transferred to member states and implemented by various authorities. It discusses the challenges of the European multi-level governance structure and the main causes of policy failure or…
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De rol van verwachtingen en vermijdingsleren bij de instandhouding van somatische symptomen
Somatische symptomen, zoals pijn, jeuk en vermoeidheid, blijken in twee richtingen samen te hangen met psychische symptomen. Hoewel acute somatische symptomen bepaalde adaptieve eigenschappen hebben, kunnen chronische symptomen in plaats daarvan leiden tot verstoring van dagelijkse activiteiten en vermindering…
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Nieuws en agenda
Het laatste nieuws over diversiteit en inclusie binnen de Universiteit Leiden en een overzicht van komende activiteiten
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Geneeskunde/LUMC
De LUMC Alumni Vereniging is in 1996 opgericht om enerzijds de band tussen het Leids Universitair Medisch Centrum en zijn alumni te versterken, anderzijds om de band van de alumni onderling te versterken.
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Sandra van Dijk helpt nierpatiënten gezonder te leven
Hoe kunnen nierpatiënten geholpen worden een gezonde leefstijl aan te nemen? Gezondheidspsycholoog Sandra van Dijk gaat dit onderzoeken met een persoonsgebonden subsidie van de Nierstichting.
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Immunological profiling in kidney transplantation through high- dimensional analysis
Promotie
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Improving Risk Stratification and Precision Immunosuppression in Kidney Transplantation
Promotie
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Circulating non-coding RNAs in kidney disease
Promotie
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Imperfections: using defects to program designer matter
Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.
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Gratis grootschalig online onderwijs: MOOCs
De gratis online academische cursussen van de universiteit zijn voor iedereen over de hele wereld te volgen.
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and spatial transcriptomics with applications in Autosomal Polycistic Kidney Disease
Promotie
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Onderwerp: Psychologische factoren bij jeuk en pijn
Aangezien jeuk en pijn zeer belastend kunnen zijn, vooral wanneer mensen chronisch aan (een van) deze symptomen lijden, is het belangrijk te weten door welke factoren deze gewaarwordingen worden beïnvloed. Het wordt steeds duidelijker dat psychologische factoren een belangrijke rol spelen bij het ervaren…