The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

feestbundel voor de Britse demotisant Cary J. Martin (UC Londen)

Linde Desmaele onderzoekt de rol van Amerikaanse tactische kernwapens in Europa. Zij stelt dat deze wapens voornamelijk dienen als instrumenten voor bondgenootschapsbeheer.

Why do sexual violence policies still fail to systematically address men and masculinities, when the need for cultural change among men has been central in public debates since #MeToo?

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

Promotores: F.H. van Lunteren, F.P. Israel

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

Promotores: J. Jonkers, K.E. de Visser

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

To study how planetary systems come into existence we study much younger systems still in formation.

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Effectiveness and Side-effects.

Cardiovascular diseases are still a major concern for the global health.

Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.

CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Quantum computers are a proposed fundamentally new type of computer. They aim to perform some computations much faster than previously possible by exploiting phenomena at the quantum scale, called superposition and entanglement.

To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.

Promotor: Prof.dr. E.F. van Dishoeck

Promotor: Prof.dr. G.P. van Wezel

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Bij de Onderzoeksgroep Geweld en Geweldpreventie (Violence and Violence Prevention) wordt onderzoek gedaan naar de complexiteit van hedendaags geweld, de uiteenlopende verschijningsvormen ervan en strategieën voor preventie.

Promotor: Prof.dr. C.W.J. Beenakker

Promotor: J. Schaye

The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Heart failure is a major health care problem with high mortality.

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

The ultimate goal of cosmologists is to find a cosmological model able to explain the current observational data.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.