Het doel van deze faciliteit is om het biomedisch onderzoek te versnellen door toegang te bieden tot geavanceerde licht- en elektronenmicroscopie en door het delen van expertise over monstervoorbereiding, beeldvormingsmodaliteiten, gegevensopslag en beeldanalyse.

Promotor: H.V.J. Linnartz

This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

Promotor: T.J. Aartsma, Co-promotor: R.N. Frese

Bussmann

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

Polycyclic aromatic hydrocarbons (PAHs) are the most abundant class of organic compounds in space. The PAH field evolves from the constant interaction between experimentalists, theorists, modellers and observers. While laboratory research and quantum chemical calculations together set up the molecular…

The goal of the research presented in this thesis was to explore the chemical space of ruthenium(II) photocages, investigate their ability to host potent chemotherapy drugs, and to red shift the activation wavelength of the most promising PACT candidates to conduct biological studies.

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.

Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.

Has the industrial sector in China effectively been decarbonizing in recent years, across different regions and subsectors, and is it plausible that it will reduce its CO2 emissions in conformity with national and internationally pledged emission goals?

De Leidse Sterrewacht gaat deelnemen aan de activiteiten van het International Year of Light (IYL). Het jaar 2015 is door de Verenigde Naties uitgeroepen tot het International Year of Light and Light-based Technologies. IYL 2015 zal aan de wereld laten zien hoe belangrijk licht en optische technologie…

De 3D-spectrograaf Multi Unit Spectroscopic Explorer (MUSE) is met succes geïnstalleerd en in gebruik genomen op de Very Large Telescope op Cerro Paranal, Chili. MUSE heeft tijdens zijn eerste waarnemingsperiode gekeken naar verre sterrenstelsels, heldere sterren en andere testobjecten. De Sterrewacht…

Het Story of Light festival dat plaatsvindt van 14 tot 18 januari 2015 in Panaji, Goa in India, is een initiatief van Jaya Ramchandani, alumnus van de masteropleiding Astronomy and Science Based Business. Het festival valt onder ‘The International Year of Light’, een project van de VN om de wetenschappelijke…

Deze week ging de documentaire ‘Einstein’s Light’ tijdens het Leiden International Film Festival (LIFF) in première.

Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.

Promotor: Prof.dr. M.K. Richardson

Promotor: Prof.dr. H.J.M. de Groot, Co-promotor: Francesco Buda

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

This thesis discusses the discovery potential of Intensity Frontier experiments.

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

Promotie

Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

Promotor: R. Gill, Co-promotor: P. Massart

Promotor: M.A.G.J. Orrit

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

To study how planetary systems come into existence we study much younger systems still in formation.

When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…