Promotor: Prof.dr. T. Schmidt

Onze medewerkers en studenten maken deel uit van de taskforces van Una Europa. Deze taskforces vertalen de kernthema’s van Una Europa naar concrete acties.

Promotor: T. H. Oosterkamp

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Promotor: T.H. Oosterkamp

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

In this dissertation, we work towards an experiment in which we aim to bring a micrometer sized magnet at the tip of a soft cantilever into a superposition.

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Op 9 januari 2019 verdedigde Willem van der Muur zijn proefschrift 'Land rights and the forces of adat in democratizing Indonesia'. Het promotieonderzoek is begeleid door promotoren prof. dr. A.W. Bedner en prof. dr. J.M. Otto.

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Op 9 mei 2018 verdedigde Roy van Keulen zijn proefschrift 'Digital Force: Life, Liberty & Livelihood in the Information Age'. Het promotieonderzoek is begeleid door promotor prof.dr. A. Ellian.

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Political scientist Corinna Jentzsch (Leiden University) about the organisation of rebel and government auxiliaries in the civil war in Mozambique (1976–1992).

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Op 17 oktober verdedigde Annelies van Vark het proefschrift 'Separation and immersion: the changing role of the armed forces in Northwestern liberal democracies'. Het promotieonderzoek is begeleid door Maartje van der Woude en Erwin Muller.

In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.

Een verhaal van Twee Mosuls, De wederopstand van de Irakese strijdkrachten en de militaire nederlaag van ISIS. In dit artikel, gepubliceerd in het Journal of Strategic Studies, bespreken de auteurs Maarten Broekhof, Martijn Kitzen en Frans Osinga de militaire aanpassing door de Iraakse strijdkrachten…

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort

Op 21 juni sprak Jorrit Rijpma op de eerste bijeenkomst van het Task Force over een Europese Grens- en Kustwacht, opgericht door het Centre for European Policy Studies in Brussel.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Promotor: Prof.dr. J.W.M. Frenken

This thesis investigates reactive interfaces in surface science across three domains: heterogeneous catalysis, environmental nanoplastics, and two-dimensional materials.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

Tentoonstelling

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Lezing, Tuesday Talks: Science Insights

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

The origin and evolution of galaxies are closely linked to many different physical phenomena.

Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

Promotor: Prof.dr. S. Haring

Promotie

Mechanical interactions between cells and their environment play an important role in many biological processes.

Met elektronspins hebben natuurkundigen het bindingsproces onderzocht van het eiwit α-synucleïne, dat wordt geassocieerd met de ziekte van Parkinson. Wat blijkt is dat het eiwit op een verrassend efficiënte manier bindt aan een hersenmembraan. Met deze in Leiden ontwikkelde methode hebben de onderzoekers…

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

Una Europa biedt veel mogelijkheden voor ondersteunend personeel.

Per dag verliezen we vijf mensen door zelfdoding. Onderzoekers van 113 Zelfmoordpreventie en Universiteit Leiden werken komend anderhalf jaar samen met 25 partnerorganisaties om suïcidepreventie in de zorg te verbeteren. ‘We willen dat bewezen effectieve behandelingen sneller kunnen worden toegepast…

Promotor: T. Schmidt

Meer dan 500.000 studenten en bijna 100.000 universiteitsmedewerkers in heel Europa maken deel uit van onze Una Europa-gemeenschap.

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.