1,512 zoekresultaten voor “digital and audiovisual methods” in de Publieke website
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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Haico van Attikum
Faculteit Geneeskunde
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Céline Zaepffel
Faculteit der Geesteswetenschappen
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Paulus Quax
Faculteit Geneeskunde
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Dorien Peters
Faculteit Geneeskunde
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Mila van Nieuwenhuizen
Faculteit der Geesteswetenschappen
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Joeri Lammerts
Faculteit Governance and Global Affairs
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Cornelis Hokke
Faculteit Geneeskunde
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Dancing with the Stars
This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.
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the C&D waste management systems in the Netherlands, Belgium, Spain and Finland
What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…
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Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Chaotic dynamics in N-body systems
Promotor: Prof.dr. S.F. Portegies Zwart
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Error bounds for discrete tomography
Promotores: K.J. Batenburg, B. Koren
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Tijmen Baarda
Universitaire Bibliotheken Leiden
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Bayesian learning: challenges, limitations and pragmatics
This dissertation is about Bayesian learning from data. How can humans and computers learn from data?
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Computational electrocatalysis
This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Radicals in arithmetic
Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit
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Angus Mol nieuwe directeur LUCDH: ‘We willen een aanspreekpunt zijn’
Het Leiden University Centre for Digital Humanities (LUCDH) heeft per 1 februari een nieuwe directeur. Universitair hoofddocent Angus Mol wil in zijn nieuwe rol mensen en kennis verbinden.
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Applications of topology to Weyl semimetals and quantum computing
This thesis covers various applications of topology in condensed matter physics and quantum information.
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GEANNULEERD: Digital Twin Engineering
Lezing
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Innovative (electro-driven) sample preparation tools for metabolomics study of muscle aging
This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.
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Asia-Europe Cooperation on Inclusive Digital Societies
Webinar
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Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
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Engineering of antigen-saving dissolving microneedles for intradermal vaccine delivery
The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.
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Potential interference of fungal endophytes in Vanilla planifolia on vanilla flavor compounds biosynthesis
Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.
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LC-Impact
How can we develop and further improve life cycle impact assessment methods, characterisation factors and normalisation factors?
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Mining Sensor Data from Complex Systems
Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe
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ReCiPe
The ReCiPe methodology for Life Cycle Impact Assessment (LCIA).
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink
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Algebraic filters for filtered backprojection
Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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Reasoning about object-oriented programs: from classes to interfaces
Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…
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Novel Protecting Group Strategies in the Synthesis of Oligosaccharides
The thesis focuses on synthesis strategies in oligosaccharide campaigns, and the influence of protecting groups.
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Activity-based proteomics of the endocannabinoid system
This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.
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Simulating the birth environment of circumstellar discs
Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.
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Elsa Charlety
Faculteit der Sociale Wetenschappen
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Ancois De Villiers
Faculteit der Sociale Wetenschappen
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Simay Cetin
Faculteit der Sociale Wetenschappen
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Lotte van der Pol
Faculteit Governance and Global Affairs
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Esther van de Camp
Faculteit der Sociale Wetenschappen
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James McGrail
Faculteit der Sociale Wetenschappen
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Digital Affective Citizenship
Promotie
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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Expansions of quantum group invariants
In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.
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Searching by Learning: Exploring Artificial General Intelligence on Small Board Games by Deep Reinforcement Learning
In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Adriaan van der Weel over E-READ in Frankfurter Allgemeine Zeitung
Onderzoekers van meer dan 30 landen namen deel in het Europese onderzoeksnetwerk E-READ om de veranderingen in het lezen door digitalisering te bestuderen. Adriaan van der Weel, universitair hoofddocent, sprak over het succes van het netwerk met de Duitse krant Frankfurter Allgemeine Zeitung.