Welkom bij het project Fair Educational Assessment in the Age of AI (FAIR-ASSESS)!

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

Alumni van LUC volgen allemaal hun eigen unieke carrièrepad na hun afstuderen. Het succes van een Liberal Arts and Sciences opleiding wordt weerspiegeld in de diverse en bijzondere wegen die alumni inslaan.

Van zelfrijdende auto’s tot innovatieve medicijnontwikkeling, kunstmatige intelligentie (AI) gaat ons leven op uiteenlopende manieren fundamenteel veranderen. Onze computerwetenschappers bestuderen de technologie op een diep en fundamenteel niveau. Maar we zoeken ook naar medische toepassingen en antwoorden…

Promotores: J.C. van Houwelingen, S.A. van de Geer

De Universiteit Leiden is een van Europa’s meest vooraanstaande internationale onderzoeksuniversiteiten.

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Promotores: H. Schiessel, G.T. Barkema

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

A new publication on changes in the relationship between news and their public in Chile

Promotor: Prof.dr. C.W.J. Beenakker

The project Multimedia Research and Documentation of African Oral Genres: Connecting Diasporas and Local Audiences (Director: D.Merolla) focuses on multimedia as technology that allows scholars to share documentation and scientific knowledge with the cultural owners of the collected oral genres.

Visualizing the internal structure is a crucial step in acquiring knowledge about the origin, state, and composition of cultural heritage artifacts. Among the most powerful techniques for exposing the interior of cultural heritage objects is computed tomography (CT), a technique that computationally…

Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

De Onderzoeksgroep Geweld en Geweldpreventie aan de Universiteit Leiden richt zich op het begrijpen en voorkomen van geweld in moderne samenlevingen. De groep biedt twee belangrijke opleidingsprogramma’s aan: de Minor Violence Studies en de specialisatie Governance of Violence binnen de Master Crisis…

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

Het Centre for Professional Learning (CPL) is het expertise centrum van Universiteit Leiden in Den Haag voor leren en ontwikkelen in het publieke domein. Uitdagend, innovatief, academisch onderbouwd en praktijkgericht. CPL werkt daarbij samen met partners in diverse disciplines, sectoren, landen en…

Heart failure is a major health care problem with high mortality.

This dissertation is about Bayesian learning from data. How can humans and computers learn from data?

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Benieuwd of de opleiding International Studies aan Universiteit Leiden bij je past? Bekijk de opleidingsvideo voor meer informatie.

De master Economie van de Publieke Sector verweeft onderwijs met de nieuwste onderzoeksmethodes van de hoogste kwaliteit.

DSE 2.0: Naar een optimaal ontwerp van complexe, gedistribueerde cyber-fysieke systemen

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

Promotor: Prof.dr. W.T.F. den Hollander

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

The department of Industrial Ecology is dealing with research into the development of tools for decision making on sustainable production and consumption.

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.

Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

This thesis investigates how quantum, quantum-inspired, and hybrid quantum-classical computation can enhance key points of the automated machine learning (AutoML) pipeline under the constraints of noisy intermediate-scale quantum (NISQ) devices.

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh