De Universiteit Leiden biedt één volledige Leiden University Excellence Scholarship (LExS) aan aan een Afrikaanse kandidaat die geïnteresseerd is in de tweejarige Research Master African Studies (ResMA AS); het is dus een beurs voor niet-EER/niet-EVA*-aanvragers.

Tijdens de laatste vergadering van het bestuur van de Onderzoekschool Rechten van de Mens (School of Human Rights Research) is Jan-Peter Loof gekozen tot bestuursvoorzitter, als opvolger van Prof. dr. M. Kamminga (Universiteit Maastricht) die in april met emeritaat is gegaan.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Congres/symposium

Promotor: H.J.M. de Groot

This thesis contains results on the arithmetic and geometry of del Pezzo surfaces of degree 1.In Chapter 1 we give the necessary background, assuming the reader is familiar with algebraic geometry.

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

This thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single crystalline gold nanorods (GNRs) as our basic frameworks in the whole studies, simply because of their unique…

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

Promotor: Prof.dr. E.F. van Dishoeck

We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.

Promotor: Prof.dr. B. van de Water

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Galaxy intrinsic alignments induce a major astrophysical contamination to weak gravitational lensing measurements and need to be modelled and mitigated when extracting cosmological information from such measurements.

Promotor: I. A. G. Snellen, Co-promotor: M. A. Kenworthy

This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

Promotores: K.J. Batenburg, B. Koren

Outflows are crucially important for the gas budget and evolution of luminous star-forming galaxies and AGNs, with observed mass outflow rates of the same order as the star formation rate. Greater star formation and black hole growth lead to more intense feedback and outflows, resulting in self-regulated…

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Cardiovascular diseases (CVDs) are the leading global cause of mortality. Endothelial dysfunction, an early reversible stage of CVD development, is marked by decreased nitric oxide production linked to Ca2+ influx in endothelial cells.

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

Promotores: P. Stevenhagen, A. Enge Co-Promotor: T.C. Streng

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Hydrogen-based fuels are regarded as promising candidates for decarbonizing the maritime shipping sector.

Al tijdens je studie ontdekken of werk in de wetenschap misschien iets voor je is. Die kans krijgen studenten tijdens het facultaire Research Traineeship Programme. Vrijdag 1 september presenteerden zij hun resultaten aan elkaar en hun begeleiders.

The largest structures in the Universe are clusters of galaxies. Each can contain hundreds to thousands of galaxies.

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Promotor: H.W. Lenstra

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…

A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.

Promotor: S.J. Edixhoven

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.

Promotor: G.R. de Snoo, Co-promotores: M.G. Vijver, J.P.M. Vink

This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals