2,963 zoekresultaten voor “leiden teacher academic” in de Publieke website
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Matthieu Schaller -
ELS@Leiden
ELS@Leiden dient als platform om juristen en sociaalwetenschappers bij elkaar te brengen om tezamen juridisch relevante vragen met betrekking tot marktregulering te onderzoeken.
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Babylab Leiden
Baby's leren verbazingwekkend snel hun moedertaal (of –talen!), en ze weten van jongs af aan al veel over het gedrag van mensen en de eigenschappen van objecten. De onderzoekers van het Babylab van de Universiteit Leiden proberen te begrijpen hoe deze vaardigheden zich ontwikkelen.
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Leids Historiestuk
Over dit schilderij uit 1626 breken Rembrandtkenners zich al heel lang het hoofd. Volgens sommige interpretaties kwam de opdrachtgever uit de kringen van de universiteit. Mogelijk gaat de voorstelling over rechtspraak. Dit doek is te zien bij het Gravensteen, dat tussen 1463 en 1955 dienst deed als…
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Leiden - Indonesië
Universiteit Leiden heeft een lange samenwerkingstraditie met Indonesië.
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Leiden - China
China is een belangrijke partner voor de Universiteit Leiden. We werken samen met meer dan 20 Chinese universiteiten en in Leiden studeren zo'n 500 Chinese bachelor-, master- en PhD-studenten. Leiden heeft China aangewezen als prioriteitsland waarmee het een partnerprogramma voor langetermijnsamenwerking…
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Bio-Farmaceutische Wetenschappen in Leiden stijgt naar plek 17 in QS Ranking
Het Leidse farmacie- en farmacologieonderzoek stijgt dit jaar naar de 17e plaats op de QS World University Rankings by Subject. In 2016 stond het nog op de 21ste plaats van deze ranklijst, die jaarlijks topuniversiteiten beoordeelt op 46 vakgebieden.
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SCS Courses
The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.
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Exploring big data approaches in the context of early stage clinical
Als gevolg van de grote technologische vooruitgang in de gezondheidszorg worden in toenemende mate gegevens verzameld tijdens de uitvoering van klinische onderzoeken.
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
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Stemmen op berkenbast
Persoonlijke briefjes uit middeleeuws Rusland? We kennen wel veel officiële en kerkelijke documenten, maar de vondsten van stukjes beschreven berkenbast uit Novgorod geven op een unieke wijze inzicht in hoe 'gewone' mensen dagelijks met elkaar communiceerden.
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Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors
Promotor: A.P. IJzerman
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CE-MS for metabolomics: advancing performance and detection sensitivity
The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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Liposome-based vaccines for immune modulation: from antigen selection to nanoparticle design
Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Planning
Het Gorlaeus Gebouw wordt in drie fasen gerealiseerd. Het nieuwe gebouw is medio 2028 helemaal gereed.
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Cholesterol metabolism in mouse models of atherosclerosis and adrenal steroidogenesis
Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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Nanoparticles and Microfluidics for Future Tuberculosis Vaccines
Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.
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Bibliotheek en LU-Card
Als alumnus van de Universiteit Leiden kunt u uw hele leven lang gebruik blijven maken van de Universitaire Bibliotheken Leiden (UBL).
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Engineering of antigen-saving dissolving microneedles for intradermal vaccine delivery
The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.
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Extracellular Matrix Mechanics in the Regulation of the early steps of the Metastatic Cascade
Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Metabolomics Insights into the Gut Microbiome and Infants with Cow’s Milk Allergy
The rapid expansion of research on human gut microbiome in recent decades has highlighted its role in human metabolism, immune regulation, and behavior.
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LUdev Project Fair
Congres/symposium
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Gut Microphysiological Systems for Toxicology: Scalable Assays for Industry Implementation
Every day, the intestines face an enormous challenge. They must absorb nutrients, medicines, and other substances we consume, while keeping harmful compounds out.
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Leiden in 2019 centrum internationale kennisuitwisseling Azië
Het belangrijkste congres op het gebied van Aziëstudies kiest voor Leiden: van 16 tot en met 19 juli 2019 zal de International Convention of Asia Scholars (ICAS) in Leiden worden gehouden. Tijdens deze elfde editie van het internationale congres ontvangt de Universiteit Leiden rond de 1500 academici…
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Pingtao Ding -
Vikram Radhakrishnan -
Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.
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Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.
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Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.