Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.

The LUGO Press is a student publication forum, rooted in academia and journalistic practices and published by the Leiden University Green Office.

Around the world, mindfulness has become big business. This course combines conventional scholarly inquiry from multiple disciplines with experiential learning to provide a responsible, comprehensive, and inclusive education about mindfulness as a contemporary phenomenon.

Deze opleiding biedt de mogelijkheid om onderzoek op moleculair, cellulair en organismaal niveau te verenigen, maar biedt ook de mogelijkheid om je te specialiseren op één van deze niveaus.

What are the pressing issues of our time, and how can different disciplines come together to address them? Studium Generale and Leiden University College (LUC) present the Global Challenges series: events that bring together researchers from LUC and experts from other disciplines to tackle a shared…

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

In this dissertation (titled: Exploring the Synergies between Transfer in Reinforcement Learning and Procedural Content Generation) we explore how the two research fields named in the title, namely Transfer in Reinforcement Learning (TRL) and Procedural Content Generation (PCG) can synergize togethe…

Promotores: R. Tijdeman, K.J. Batenburg

Risk has become one of the defining features of modern society. This course examines various types of safety and security risks, and how these are perceived and dealt with in a wide array of professional and academic fields, ranging from criminology, counter-terrorism and cyber security, to philosophy,…

Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

Veel overheidsorganisaties maken gebruik van algoritmes, maar het beleid daarvoor schiet volgens de organisaties schiet vaak tekort. Dat blijkt uit een inventarisatie van het CBS onder bijna zeventig ministeries, gemeenten en andere overheden.

Promotor: Prof.dr. M.A.G.J. Orrit

Dynamical systems describe the evolution of objects in a space over time and may be used to model physical phenomena. Due to this, much research is dedicated to understanding the mathematics of dynamical systems.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

Promotor: Prof.dr. G.R. de Snoo

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Aan het LUCL pogen onderzoekers om de taaldiversiteit van de inheemse bevolking van Amerika te begrijpen, te bestuderen en te behouden.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.

This thesis was embedded in the APELAFICO project and focussed on investigating effects of sound from North Sea offshore wind farms on pelagic fish and harbour porpoise.

Understanding how nature captures and transfers solar energy is essential both for elucidating biological photosynthesis and for guiding the design of artificial light-harvesting systems.

Kiemproject: Hoe kunnen metaforen bijdragen aan betere maatschappelijke betrokkenheid bij quantumwetenschap en -technologie, en welke factoren beïnvloeden de acceptatie of weerstand tegen metaforen bij zowel experts als leken?

De opkomst van 'illiberal democracies' en de bescherming van mensenrechten in Europa

Workshop