In het Museum voor Communicatie in Den Haag is het archief van een 17e-eeuwse postmeester herontdekt. Het internationale onderzoeksteam Signed, Sealed & Undelivered, geleid door letterkundige Nadine Akkerman van de Universiteit Leiden en historicus David van der Linden van de Rijksuniversiteit Groningen,…

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

Over de hele wereld staan koraalriffen onder druk. Zarinah Waheed onderzocht de riffen in Maleisië en komt tot de conclusie dat de bescherming van koraalriffen beter kan. Promotie op 22 november.

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Hoe verandert generatieve AI de manier waarop we leren, communiceren en de wereld van vandaag begrijpen? Nu AI-tools deel uitmaken van het dagelijks leven, produceren ze niet alleen tekst, maar geven ze ook betekenis, beïnvloeden ze vertrouwen en hebben ze invloed op hoe we informatie vinden en delen.…

The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.

The specialisation Science Communication and Society (SCS) concerns science communication in a broad sense. The program focuses on the link between science and society and covers knowledge and skills in the field of science communication.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

Environmental challenges such as plastic pollution and biodiversity loss require extensive monitoring. Citizen science, in which members of the public participate in scientific research, has therefore become an important approach in environmental science.

The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

Signalen zijn essentieel voor het leven. Signalen uitzenden en signalen ontvangen doen wij doorlopend. Jeroen den Hertog, hoogleraar Moleculaire ontwikkelingszoölogie, onderzoekt de overdracht van signalen op moleculair niveau.

Tuberculosebacteriën en andere intracellulaire pathogenen gebruiken immuuncellen als paard van Troje om zich in hun gastheer te verspreiden. Annemarie Meijer, hoogleraar immunobiologie, vertelt hoe onderzoek naar mechanismen van aangeboren immuniteit in zebravissen helpt om nieuwe behandelingsmethoden…

Om goed onderbouwde besluiten over complexe onderwerpen zoals het klimaat, recht en gezondheid te kunnen nemen, zijn wetenschappelijke resultaten van groot belang. Maar wetenschappelijke resultaten bevatten altijd een mate van onzekerheid. Binnen het onderzoek Communicatie over onzekerheden wordt onderzocht…

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

The field of science communication is very broad. Below is a list of organisations where SCS students can fulfill internships or where alumni have found jobs.

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Biologiestudent Jannica Swieringa (masterspecialisatie Animal Sciences and Health) heeft de Unilever Research Prijs 2016 gewonnen voor haar onderzoek om de effectiviteit van kankergeneesmiddelen te verbeteren. Op 1 december ontving ze de prijs ter waarde van 2500 euro.

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

In this thesis we study products of linear error correcting codes.

Promotor: Prof.dr. M. Schilthuizen

To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.

Kinderen kunnen vaak zelf beslissen of ze mee willen werken aan medisch-wetenschappelijk onderzoek. Daarvoor moeten ze wel duidelijke informatie krijgen. Promovendus Ronella Grootens gaf het goede voorbeeld en maakte een stripverhaal. Promotie op 6 december.

‘Legitimacy and Justice’ is een onderzoekscluster binnen het programma ‘Institutions, Decisions and Collective Behaviour’. De wetenschappers die hierin actief zijn houden zich bezig met de legitimiteit en rechtvaardigheid van politieke instituties. Zij kijken in het bijzonder naar de relaties tussen…

Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.

Promotie

Kijk mee en praat mee over de wetenschap van het verleden tijdens wekelijkse Let’s Plays van populaire games en vodcasts op het livestreamplatform Twitch.

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

Dit project beoogt de ontwikkeling van geavanceerde data-analysemethoden voor monitoring en het vergroten van ons inzicht in de dynamiek van de biodiversiteit in natuurgebieden zoals de Oostvaardersplassen.

In this thesis, I investigated the neurogenetic properties of Neotropical bat species. Bats represent the second largest mammalian order (Chiroptera) in the world, with Neotropical bats constituting about 13% of the total number of bat species.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.