Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Promotor: Prof.dr. M. Ubbink

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Promotor: K.H. Kuijken

The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Op de eerste dag van jouw nieuwe baan heb je zweethanden, ben je nerveus en onzeker, maar een paar maanden later zijn die gevoelens al weer verdwenen. Je hebt jouw nieuw rol eigen gemaakt en je bent nu onderdeel van de organisatie. Het proces dat daar naar toe leidt heet

The Role and Effectiveness of the G20. In dit artikel, gepubliceerd in The Changing Global Order onderdeel van the United Nations University Series on Regionalism book series, bespreekt auteur Jaroslaw Kantorowicz de evolutie van de G20.

Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

Op 19 december 2019 verdedigde Reza Eftekhar zijn proefschrift 'The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival of the Localisation Theory'. Het promotieonderzoek is begeleid door promotor prof.dr. E.…

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Promotor: Prof.dr. B.R. Katzy

Promotor: A.P. IJzerman

Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

Tin electrodeposition applications have rapidly evolved in the past 25 years.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

Promotor: Prof.dr. J. Kuiper

This dissertation is part of a broader research project that revolves around unraveling the evolution of balanced lethal systems.

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Promotor: G. van Dijk

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

Promotor: Prof.dr.ir. E. Deprettere

Op 7 september verdedigde Francesc Claret Traid het proefschrift 'On the nature of the right to resist: a rights-based theory of the ius resistendi in liberal democracies'. Het promotieonderzoek is begeleid door Afshin Ellian en Gelijn Molier.

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

In dit artikel onderzoeken Madeleine O. Hosli en Wen Pan hoe intergouvernementele dynamieken het Europees Stabiliteitsmechanisme vormgaven, waarbij ze Liberale Intergouvernementalisme gebruiken om onderhandelingsfasen, de invloed van grote lidstaten en de geldigheid van theoretische aannames te anal…

In dit artikel onderzoeken Jaroslaw Kantorowicz en zijn coauteurs hoe recente politieke veranderingen het Poolse Grondwettelijk Tribunaal hebben hervormd en waarom deze ontwikkeling belangrijke inzichten biedt in hedendaagse democratische achteruitgang in Europa.

Op 12 februari promoveert Cid Swanenvleugel. Het Leiden University Centre for Linguistics feliciteert Cid!

Langetermijnontwikkelingen, zoals het verouderen van de bevolking, de toename in de gemiddelde levensverwachting en de gevolgen van de recente financiële crisis, hebben bijgedragen aan de discussie rondom de houdbaarheid van het pensioenstelsel.