The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.

The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).

In this thesis, we present new laboratory data of interstellar dust analogues.

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Data reuse en big data: een ordening voor persoonlijke data reuse.

Het gebruik van ‘Big data’ is niet meer weg te denken binnen het wetenschappelijk onderzoek. Voor dit onderzoek maken we gebruiken van diverse grote databestanden.

Promotor: Prof.dr. J.W.M. Frenken

Promotor: Prof.dr. M. de Jong

The origin and evolution of galaxies are closely linked to many different physical phenomena.

Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

Nowadays, it is well known that hydrogen and helium (and small traces of lithium and beryllium) were created shortly after the Big Bang, while the heavier elements are created in the cores of stars at different evolutionary stages. When these stars explode as supernovae, they expel metals synthesised…

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

The role of the interfacial environment during electrochemical reactions has been increasingly valued, especially for those reactions involving protons or hydroxyl ions.

Data Sets afdeling Economie

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).

Quantum computers are a proposed fundamentally new type of computer. They aim to perform some computations much faster than previously possible by exploiting phenomena at the quantum scale, called superposition and entanglement.

Het verzamelen en interpreteren van grote hoeveelheden data is niet meer weg te denken uit de maatschappij en de wetenschap. De Universiteit Leiden is een kennis- en expertisecentrum van data science dat de nadruk legt op interdisciplinaire samenwerking en innovatie.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Het merendeel van de wetenschappers, van archeologen tot zoölogen, verzamelt enorme hoeveelheden gegevens. Hun databanken bevatten grote hoeveelheden informatie die voor de mens moeilijk te filteren zijn. Met een stevige basis in de statistiek en de computerwetenschappen kunnen we algoritmes ontwikkelen…

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

Het merendeel van de wetenschappers, van archeologen tot zoölogen, verzamelt enorme hoeveelheden gegevens. Hun databanken bevatten grote hoeveelheden informatie die voor de mens moeilijk te filteren zijn. Met een stevige basis in de statistiek en de computerwetenschappen kunnen we algoritmes ontwikkelen…

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Studievoorlichting

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Patients share valuable advice and experiences with their peers in online patient discussion groups.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Promotor: Prof.dr. W.J.G.M. Peijnenburg

De masteropleiding Statistics & Data Science is een tweejarige master waarbij een diep doorgronde introductie wordt gelegd aan de algemene filosofie en methodologie van statistische modellen, statistisch modelleren, data analyse en data science, met de voornaamste focus op toepassingen in levens- en…

Tomography is a powerful technique to non-destructively determine the interior structure of an object.Usually, a series of projection images (e.g.\ X-ray images) is acquired from a range of different positions.

Sport Data Center

Het Data Science Onderzoeksprogramma (DSO) ​​​​is een universiteitsbreed programma dat erop gericht is de kwaliteit van het bestaande data science-onderzoek te verhogen en het gebruik van data science-methoden te bevorderen bij alle faculteiten van de Universiteit Leiden.

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Data Science (DS) and Artificial Intelligence (AI) are omni-present and have the potential to be incorporated in various fields. However, in order to live up to this expectation, a good understanding of the techniques, their implications and limitations is required. In this minor you develop insights…

Data, prijs & locatie

Data, prijs & locatie van de cursus Gendergerelateerd Geweld