958 zoekresultaten voor “molecular genetica” in de Publieke website
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Causing a stir: Radiative and mechanical feedback in starburst galaxies
Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf
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Contributions to the phylogeny of the haplolepideous mosses
The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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UV Photodesorption and Photoconversion of Interstellar Ices
This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.
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Medicijnen op maat? Dan moet je verder kijken dan genetica alleen
Waarom werkt een medicijn bij de één heel goed, maar veroorzaakt het bij de ander vervelende bijwerkingen? Onderzoek van Laura de Jong laat zien dat naast verschillend DNA, andere medicijnen of ziekte van invloed kunnen zijn.
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The relation between dynamics and activity of phospholipase A/acyltransferase homologs
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.
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Molecular Profiling and Immunotherapy in the Real-Life Clinical Setting in Non-Small Cell Lung Cancer
Promotie
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Molecular mystery in space
The space between the stars isn't simply a void; it also contains substances such as methanol and carbon dioxide. So far, chemical theories have been unable to explain how these substances originate under circumstances that should make it impossible. Fedor Goumans has been awarded a Veni subsidy to…
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
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Dorien PetersFaculteit Geneeskunde
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Margo DonaWiskunde en Natuurwetenschappen
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Hoe een Spaanse postdoc scheikunde-kennis naar de Leidse genetica brengt
Met een bachelor, master en PhD in scheikunde, schakelde Elena Sánchez López over naar een meer biologisch onderzoeksproject. Haar studie en PhD heeft ze afgerond aan de Universiteit van Alcala in Spanje, voordat ze een voorstel indiende in het LEaDing Fellows programma, een Marie Sklodowska-Curie Cofund…
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Breaking & Entering: PAH photodissociation and top-down chemistry
Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.
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Transformation and sublimation of interstellar ices: insights from laboratory experiments and astronomical observations
Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.
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Electronic spectroscopy of molecules of astrophysical interest
This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).
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Semi-empirical approach to the simulation of molecule-surface reaction dynamics
Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.
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Phylogeny and species delimitation within the moss genus Dicranum Hedw.
Promotor: Prof.dr. E. Smets, M. Stech
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar
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Genetica wijst uit: het Indo-Europees kwam niet te paard naar Europa
Paarden werden voor het eerst getemd in Zuidwest-Rusland, concludeert een internationaal team van wetenschappers in het gerenommeerde tijdschrift Nature. Daarmee lossen zij een oud archeologisch vraagstuk op. Maar die domesticatie heeft opvallend genoeg niet bijgedragen aan de snelle verspreiding van…
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Functionalized two-dimensional membranes and materials for solar-to-fuel devices: a multiscale computational approach
In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.
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Unraveling the auxin mechanism in 2,4-D induced somatic embryogenesis in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa
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18-jarige Molecular Science & Technology afstudeerder wil iets betekenen voor de chemie
Op 11 november organiseerde de bacheloropleiding Molecular Science and Technology een corona-proof diploma-uitreiking met een bijzondere afstudeerder: de 18-jarige Ruard van Workum. Al van jongs af aan ontwikkelde Ruard een passie voor scheikunde. Hij begon op 15-jarige leeftijd met de opleiding Molecular…
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Surface Temperature and the Dynamics of H2 on Cu(111)
Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…
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The formation of complex organic molecules in dense clouds-Sweet results from laboratory
Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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State-resolved studies of CO2 gas-surface reactions
The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.
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Diagnostics for mechanical heating in star-forming galaxies
Promotor: F.P. Israel, Co-Promoter: R. Meijerink
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Vlinder heeft ieder seizoen een ander patroon
Een tropisch vlindertje past zich aan aan zijn omgeving en creëert zo betere overlevingskansen. Dit wordt veroorzaakt door hormoonsignalen, die informatie over de temperatuur doorgeven aan weefsels van de vlinder. Bioloog Ana Rita Mateus laat zien hoe een complex samenspel van omgeving, fysiologie…
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Copper complexes for bioinspired electrocatalysis relevant to the reduction of oxygen
This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Frank BaasFaculteit Geneeskunde
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Kevin GroenWiskunde en Natuurwetenschappen
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Molecules during stellar formation and death
Promotor: Prof.dr. E. F. van Dishoeck
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Exploring the chemical space of natural products from Streptomyces using multi-omics approaches
The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.
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Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
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Chemical reactivity of O2, CO and CO2 on Cu surfaces
Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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‘Afstand kunnen nemen is belangrijk’
Julie Rutten licht een van haar stellingen bij haar promotie toe. De achtergrond van de stelling is dat ze haar partner ontmoette in het LUMC-laboratorium van humane genetica waar ze haar onderzoek deed. ‘Voor mij was een dergelijke relatie altijd 'no go'.’
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Cold gas in distant galaxies
The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.
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Niels van der WindtWiskunde en Natuurwetenschappen
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Video: Krijg je grijze haren van stress?
Dat stress ongezond is, weet je vast wel. Maar word je er ook sneller oud van? In een college van de Universiteit van Nederland vertelt psycholoog Marieke Tollenaar dat teveel stress niet heel bevorderlijk is voor je jeugdige uitstraling.
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Mononuclear spin-transition materials based on the bapbpy scaffold
Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet
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Lost in Chemical Space, Found in Data
Developing new medicines is one of modern science's most significant hurdles, a process marked by high costs, long timelines, and frequent failures of promising candidates.
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West- en Centraal-Afrikaanse leeuw genetisch anders dan andere leeuwen
Leeuwen in West- en Centraal Afrika verschillen opvallend van leeuwen in het oosten en zuiden van Afrika. Dat blijkt uit genetisch onderzoek door wetenschappers van het Institute of Environmental Sciences en het Instituut Biologie Leiden. Ze werkten samen met onderzoekers van verschillende universiteiten.…