• Publieke website
• Studentenwebsite
• Medewerkerswebsite
• Organisatiegids
• Bibliotheekwebsite

210 zoekresultaten voor “strategy” in de Publieke website

• Structural Health Monitoring Meets Data Mining Onderzoeksoutput

  Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

• Getting personal: Advancing personalized oncology through computational analysis of membrane proteins Onderzoeksoutput

  Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

• Developing metabolomics for a systems biology approach to understand Parkinson's disease Onderzoeksoutput

  Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

• Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts Onderzoeksoutput

  Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

• Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines Onderzoeksoutput

  The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

• Disrupting the transcriptional machinery to combat triple-negative breast cancer Onderzoeksoutput

  Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

• ALL-IN meta-analysis Onderzoeksoutput

  Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.

• Morphogenesis and heterogeneity in liquid-grown streptomyces cultures Onderzoeksoutput

  The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

• Synthetic carbohydrate ligands for immune receptors Onderzoeksoutput

  One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

• Affinity-based profiling of the adenosine receptors Onderzoeksoutput

  The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

• Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing Onderzoeksoutput

  Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

• Impact of land use changes on the human-elephant conflict Onderzoeksoutput

  Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh

• Lipid nanoparticle technology for mRNA delivery: Bridging vaccine applications with fundamental insights into nano-bio interactions Onderzoeksoutput

  Lipid nanoparticles (LNPs) have enabled the success of mRNA vaccines but remain limited in broader therapeutic use by challenges in delivery efficiency, targeting, and mechanistic understanding.

• Targeting bacterial pathogens with next-generation glycoconjugate vaccines Onderzoeksoutput

  This thesis investigates innovative and classical strategies in glycoconjugate vaccine development to address the growing threat of multidrug-resistant bacterial infections.

• Puzzling pyrophosphates: synthetic methodologies for ADP-ribosylated biopolymers Onderzoeksoutput

  This thesis focuses on developing new chemical synthesis strategies to produce native ADP‑ribosylated biomolecules with precise structural control.

• Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches Onderzoeksoutput

  Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

• Tools for real-time study of bioorthogonal conversions in the living system Onderzoeksoutput

  Traditional biochemical methods for studying organelles require cell disruption, preventing the real-time observation of dynamic intracellular processes.

• The opportunities for urban food self-sufficiency through green roofs: Modeling, Optimization, and Policy Scenario Analysis Onderzoeksoutput

  Conventional food supplies procured from rural areas are increasingly vulnerable to disruptions caused by extreme weather, geopolitical instability, and logistical bottlenecks.

• Computational tools and protocols for the development of photoactivated metallodrugs Onderzoeksoutput

  Metal-organic compounds hold great promise as photoactivated chemotherapy (PACT) agents, leveraging their unique geometric and electronic properties to achieve precise spatiotemporal control over drug activation.

• 
  Arjan Zuidhof SOC Security Specialist

  ISSC

• Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches Onderzoeksoutput

  Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

• Understanding the complexity of intelligence problems Onderzoeksoutput

  The complexity of an intelligence problem determines to a great extent the certainty that can be provided by intelligence and security services.

• Disentangling drought-responsive traits with focus on Arabidopsis Onderzoeksoutput

  In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

• Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture Onderzoeksoutput

  Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

• The gendered micropolitics of hiding and disclosing: assessing the spread and stagnation of information on two new EMTCT policies in a Malawian Onderzoeksoutput

  Announcement of a new publication by Janneke Verheijen, lecturer at the Institute of Cultural Anthropology and Development Sociology.

• Instituut voor Fiscale en Economische vakken

  Onder het Instituut voor Fiscale en Economische vakken van de Faculteit der Rechtsgeleerdheid vallen de afdelingen Belastingrecht, Economie en Bedrijfswetenschappen.

• Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model Onderzoeksoutput

  Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

• Artificiele Intelligentie en Ethiek bij de Politie Onderzoeksproject

  Artificiele Intelligentie en Ethiek bij de Politie

• Evolution and development of orchid flowers and fruits Onderzoeksoutput

  To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.

• Direct and two-step activity-based profiling of proteases and glycosidases Onderzoeksoutput

  Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

• 
  Inger Schipper Hoogleraar

• Onderzoek Bedrijfswetenschappen

  Onze onderzoekers vormen een uniek en interdisciplinair team dat op veel terreinen actief is.

• Wild versus domestic prey in the diet of tigers Onderzoeksoutput

  A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.

• Werken bij het ISSC van de Universiteit Leiden

  Werken aan ICT bij een topuniversiteit? Met uitstekende carrièremogelijkheden? Ontdek het werken bij het ICT Shared Service Centre van de Universiteit Leiden.

• The aging B cell landscape in atherosclerosis Onderzoeksoutput

  In this thesis, single-cell approaches were applied to characterize the impact of aging on the immunological B cell landscape in different models of atherosclerotic cardiovascular disease, with the goal to identify and study new B cell-associated biomarkers and therapeutic targets to halt atherosclerosis…

• 
  Johan den Dunnen Emeritus hoogleraar

• 
  Willem Jan Bos Bijzonder hoogleraar

• 
  Marjanka Schmidt Bijzonder hoogleraar

• 
  Douwe Biesma Hoogleraar

• 
  André Baranski Emeritus hoogleraar

• 
  Bert van Hemert Hoogleraar

• 
  Jian Wang Gastonderzoeker

  Faculteit der Sociale Wetenschappen

• Publicaties Leiden Advocacy Project on Plastic

  Hieronder vind je een overzicht van de publicaties van LAPP.

• 
  Frits Rosendaal Hoogleraar

• 
  Thea Vliet Vlieland Hoogleraar

• 
  Enrico Lopriore Hoogleraar

• 
  Michiel van de Sande Hoogleraar

• 
  Robert Vermeiren Hoogleraar

• 
  Ria Reis Emeritus hoogleraar

• 
  Nienke Biermasz Hoogleraar