This research delves into a region of space known as the interstellar medium (ISM), which is essentially the area between the stars filled with gas and dust.

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

Obesity may alter how a person absorbs, distributes, metabolizes or excretes medication. This thesis describes how obesity affects drug levels in the blood for antimicrobial agents, such as ciprofloxacin and fluconazole.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Promotores: F.H. van Lunteren, F.P. Israel

In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin

This dissertation, Layered Loyalties: The Natuurkundige Commissie in the Netherlands Indies (1820-1850), studies the Natuurkundige Commissie.

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

This thesis investigates reactive interfaces in surface science across three domains: heterogeneous catalysis, environmental nanoplastics, and two-dimensional materials.

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

This thesis investigates how quantum, quantum-inspired, and hybrid quantum-classical computation can enhance key points of the automated machine learning (AutoML) pipeline under the constraints of noisy intermediate-scale quantum (NISQ) devices.

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

Migratie is van alle tijden. Toen de Verenigde Staten werd ‘herontdekt’, trokken veel mensen daar naartoe. Ook Nederland koloniseerde een deel van Amerika en gaf het de naam Nieuw-Nederland. Masterstudent Geschiedenis Pepijn Doornenbal doet onderzoek in de VS naar hoe er in Nieuw-Nederland werd omgegaan…

Promotie

Zwolse agenten rukten uit voor de aanranding van een minderjarig meisje. Berichten hierover werden door de politie via Instagram Stories gedeeld. Op een van die berichten was een foto te zien van een mutatierapport, waarop de naam van het slachtoffer en de locatie van de aanranding niet goed waren w…

Jongeren besteden heel veel van hun tijd online. Toch weten we nog weinig over hoe dit intensieve (sociale) mediagebruik hun ontwikkeling beïnvloedt. Hersenonderzoeker en Spinozapremie-winnaar Eveline Crone van de Universiteit Leiden beschreef samen met mediapsycholoog Elly Konijn (VU) wat de wetenschap…

De gemeente Amsterdam heeft veel last van groepen hangjongeren. Om dit aan te pakken, werden de Facebook-gegevens van deze jongeren verzameld en geanalyseerd.

Het lijkt er steeds meer op dat Elon Musk in z'n eentje bepaalt wat er wel of niet op Twitter mag worden gezegd. Hij kocht het platform met de boodschap dat er alle ruimte moet worden geboden om te kunnen zeggen wat je wil, maar dat uitgangspunt brengt hij nu zelf aan het wankelen.

Lezing, Faculty Lecture

Promotie

Wetenschapper Eveline Crone zet zich samen met astronaut André Kuipers en kunstenaar Daan Roosegaarde in voor het Weekend van de Wetenschap op zaterdag 6 en zondag 7 oktober 2018. De drie ambassadeurs zijn op diverse locaties aanwezig om het publiek kennis te laten maken met de innovatieve en nieuwsgierig…

Hoe ga je weer aan het werk na een wetenschappelijke integriteitsonderzoek? Sociaal psycholoog Lotte van Dillen reflecteert in NRC vanuit haar toenmalige rol als onderzoeksdirecteur bij het Instituut Psychologie op het stilzwijgen dat vaak volgt na een integriteitskwestie. 'Belangrijk dat ervaringsdeskundigen…

Promovendus Vincent Koeman wil dat echt iedereen met quantum in aanraking komt. Hoe hij dat doet? Met een quantum pop-up tentoonstelling in de lokale bibliotheek én op Lowlands Science. Hij vertelt erover in het Leidsch Dagblad en New Scientist.

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Een groep van elf studenten van het Leiden University College en de Advanced Master International Relations and Diplomacy bezochten van 11 tot 13 April 2019 Porto om een 'Hybrid Threats' simulatie bij te wonen in het kader van 70 jaar NAVO. De deelname van de Universiteit Leiden werd gefaciliteerd door…

Promotie