Lees boeken, luister naar podcasts en bekijk films over racisme, discriminatie en het koloniale verleden.

De Partij voor de Dieren spande een kort geding aan tegen de Staat der Nederlanden om te eisen dat iedereen per post kan stemmen. Is het discriminatie dat het nu alleen voor zeventigplussers mogelijk is gemaakt en jongeren met een kwetsbare gezondheid deze mogelijkheid niet krijgen?

Van der Woude en Rodrigues hebben een artikel geschreven in het Nederlands Juristenblad over proactieve politiecontrole naar etnische afkomst en nationaliteit.

De reikwijdte van het strafrecht moet wat betreft racisme en bedreigingen op het internet niet worden overschat', zegt Peter Rodrigues, hoogleraar immigratierecht en deskundige op het gebied van racisme en discriminatie aan de Universiteit Leiden.

Een apotheker in Nieuwegein weigert zorg aan onder meer trans personen vanwege zijn religieuze overtuigingen. Mirjam Sombroek van Doorm, hoogleraar Recht en Gezondheid, stelt in NRC: ‘Patiënten mogen niet worden gediscrimineerd.’

Bekende Nederlander Sylvana Simons heeft zich onlangs aangesloten bij de politieke partij Denk. Vanaf dat moment valt een niet aflatende stroom aan discriminerende uitlatingen via sociale media te bespeuren. Ook Peter Rodrigues, hoogleraar immigratierecht - onder meer gespecialiseerd in discriminatie…

Aangezien jeuk en pijn zeer belastend kunnen zijn, vooral wanneer mensen chronisch aan (een van) deze symptomen lijden, is het belangrijk te weten door welke factoren deze gewaarwordingen worden beïnvloed. Het wordt steeds duidelijker dat psychologische factoren een belangrijke rol spelen bij het ervaren…

Positieve verwachtingen kunnen het gevoel van jeuk beïnvloeden en placebo-effecten oproepen, terwijl negatieve verwachtingen nocebo-effecten bij jeuk kunnen veroorzaken. Er zijn aanwijzingen dat placebo-effecten ook kunnen optreden wanneer mensen weten dat zij een placebo innemen. Er is weinig bekend…

Promotor: Prof.dr. L.J. Slikkerveer

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Heart failure is a major health care problem with high mortality.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

Promotor: W. Jiskoot, Co-promotor: A. Hawe

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Promotor: Prof.dr. B. van de Water

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotores: J. Jonkers, K.E. de Visser

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

Promotor: S.M. Verduyn Lunel

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa

Obesity may alter how a person absorbs, distributes, metabolizes or excretes medication. This thesis describes how obesity affects drug levels in the blood for antimicrobial agents, such as ciprofloxacin and fluconazole.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

The goal of the research presented in this thesis was to explore the chemical space of ruthenium(II) photocages, investigate their ability to host potent chemotherapy drugs, and to red shift the activation wavelength of the most promising PACT candidates to conduct biological studies.

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

De LUMC Alumni Vereniging is in 1996 opgericht om enerzijds de band tussen het Leids Universitair Medisch Centrum en zijn alumni te versterken, anderzijds om de band van de alumni onderling te versterken.

The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.