1,662 zoekresultaten voor “de factors status” in de Publieke website
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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Swimming Bass under Pounding Bass: fish response to sound exposure
Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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Computational modeling of cellular dynamics in tumor cell migration
Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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Cheating belowground interactions
Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.
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Mechanical and genetics basis of cellularization and serosal window closure in Tribolium castaneum
The applications of studying the early development of insects range from agriculture to material science.
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Early Dutch Radio Astronomy (1940-1970)
Promotores: F.H. van Lunteren, F.P. Israel
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Surviving embryogenesis: The extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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Graphene at fluidic interfaces
In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…
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Corporate venture management in SMEs: evidence from the German IT consulting industry
Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)
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Towards understanding the toxicity of copper nanoparticles in aquatic ecosystems
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Human-lion conflict around nairobi national park
Large carnivore population is globally declining as a result of the fragmentation of habitat, large prey depletion and retaliatory killing by pastoralists.
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Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
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Impact of insect herbivory and microbial inoculants on the rhizosphere microbiome and volatilome
This thesis aims to investigate the effect of tripartite interaction between microbial inoculants, the plant, and herbivore insects on the rhizosphere microbiome and volatilome. We investigated the rhizosphere microbiome and volatilome of tomato plants exposed to insect herbivory and/or inoculated with…
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Structure-reactivity relationships in glycosylation chemistry
In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.
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Heme biosynthesis and regulation in the filamentous fungus Aspergillus niger
Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel
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Evolvability and epistasis studied through the lens of an antibiotic resistance enzyme
Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Split Jacobians and Lower Bounds on Heights
This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.
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Estimation and Optimization of the Performance of Polyhedral Process Networks
Promotor: Prof.dr.ir. E. Deprettere
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Surface-structure dependence of water-related adsorbates on platinum
Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink
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Environmental sustainability of NdFeB magnet recycling: foresight study on recycling systems and technologies
The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.
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RAISE Onderzoek
Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Morphogenesis and heterogeneity in liquid-grown streptomyces cultures
The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.
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Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
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Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
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Remote (sensing) functional biodiversity: exploring drivers of trait variation and spectral variability in the Arctic
Globally and regionally, biodiversity is declining and there are shifts in species’ occurrences and functional traits.
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Exploring novel regulators and enzymes in salicylic acid-mediated plant defense
Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.
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Fire and grazers in the West African savanna
Promotores: H.A. Udo de Haes, H.H.T. Prins, Co-promotor: H.H. de Iongh
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Individualization of Drug Clearance Predictions and Dose Regimens in Patients with Obesity Using Pharmacometric Approaches
This thesis aims to develop model-based approaches to optimize drug dosing in patients with overweight and (morbid) obesity.
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Wetenschappelijke artikelen
Het Dappere Kleintjes onderzoeksteam heeft al meerdere artikelen gepubliceerd over angst en verlegenheid in jonge kinderen.
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Algemene broedvogels doen het in Nederland beter dan in Europa
De Nederlandse broedvogels zijn in de periode 1980 tot 2010 gemiddeld talrijker geworden. De algemene soorten hebben het zelfs beter gedaan dan de vogels in andere Europese landen. Uitzondering zijn de vogels van het boerenland: die gingen zowel in Nederland als elders in Europa sterk achteruit.
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Rik de RuiterFaculteit Governance and Global Affairs
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The Role of Immune Regulating Factors in the Development of Vein Graft Atherosclerosis
Promotie
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MS@Work studie
Factoren van invloed op arbeidsparticipatie onder mensen met multiple sclerose
- Nederlands voor aspirant-studenten - Examens TUL half gevorderd en TUL gevorderd
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Small molecule inhibitors of Nicotinamide N-Methyltransferase (NNMT)
NNMT wordt beschouwd als een nieuw potentieel farmacologisch doelwit in de behandeling van een verscheidenheid van kankers, stofwisselingsziekten en andere pathologieën. Het toenemend aantal publicaties waarin de rol van NNMT bij ziekten wordt opgehelderd, heeft op zijn beurt de ontwikkeling van krachtige…
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Discovery of antibiotics and their targets in multidrug-resistant bacteria
Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.
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Onderwijs
Het CLEI verzorgt een aantal vakken op het gebied van ondernemerschap en innovatie in juridische dienstverlening.
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Temminck's Order. Debates on Zoological Classification: 1800-1850
“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Cross-border Claims to Cultural Objects
Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).
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De Handels- en samenwerkingsovereenkomst tussen de EU en het VK: partnerschap of conflictbeheersing?
In dit artikel, gepubliceerd in het Nederlands tijdschrift voor Europees recht, bieden dr. J.E. Larik en prof. R.A. Wessel (Rijksuniversiteit Groningen) een kritische analyse van de handels- en samenwerkingsovereenkomst (HSO) die sinds 2021 de hoeksteen van de post-Brexit betrekkingen tussen de Europese…
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Onderzoek
De programmagroep Opvoeding & ontwikkeling doet onderzoek naar gehechtheid, sensitief opvoedgedrag en preventie van en interventie bij problemen.
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‘The Eurasian Question’: The postcolonial dilemmas of three colonial mixed-ancestry groups compared
Waarom kozen sommige Euraziërs ervoor in de voormalige kolonie te blijven, terwijl anderen naar de metropool of een ander land vertrokken?
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Deadline voor aanmelden
Je kan je aanmelden voor studiejaar 2026-2027 vanaf 1 oktober 2025.