Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

On 10-12 October 2024, a workshop is held at the University of Groningen, titled: "25 years after Hillenbrand: New Approaches to Sources, Translation and Perspectives". The organisers aim to gather specialists and early career researchers in the field of crusader studies to discuss emerging research…

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

Promotor: Prof.dr. B.R. Katzy

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Promotor: E.F. Smets Co-promotor: J. Geml

De strategische alliantie Leiden-Delft-Erasmus Universities bestaat tien jaar in 2022. Tijdens de jubileumbijeenkomst ‘The Next Ten Years’ in de Faculty Club op 12 april keken de partners terug op wat er bereikt is en werd er vooruitgekeken naar de grote maatschappelijk uitdagingen van de komende tien…

Op 7 september verdedigde Francesc Claret Traid het proefschrift 'On the nature of the right to resist: a rights-based theory of the ius resistendi in liberal democracies'. Het promotieonderzoek is begeleid door Afshin Ellian en Gelijn Molier.

The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Op deze pagina vindt u de opnames van de online This Week's Discoveries vanaf 12 mei 2020 en een lijst sprekers vanaf oktober 2015.

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

Het Leiden University Centre for the Arts in Society (LUCAS) onderzoekt beeldende kunsten, design, film, fotografie, digitale media en literatuur in de westerse wereld.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.

During the course of drug discovery translational steps are made.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

De Afdeling Jeugdrecht en Defence for Children nodigen u van harte uit voor de uitreiking van de vierde Jaap Doek Kinderrechtenscriptieprijs en de officiële presentatie van het boek ‘The United Nations Convention on the Rights of the Child. Taking Stock after 25 Years and Looking Ahead’.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.

In dit artikel onderzoeken Madeleine O. Hosli en Wen Pan hoe intergouvernementele dynamieken het Europees Stabiliteitsmechanisme vormgaven, waarbij ze Liberale Intergouvernementalisme gebruiken om onderhandelingsfasen, de invloed van grote lidstaten en de geldigheid van theoretische aannames te anal…

Promotor: Prof.dr. E. Bouwman

Op 31 januari 2018 verdedigde Vestert Borger zijn proefschrift getiteld ‘The Transformation of the Euro: Law, Contract, Solidarity’. Het promotieonderzoek is begeleid door professor Stefaan Van den Bogaert (promotor) en dr. Jorrit Rijpma (co-promotor).

Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.

Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

In dit artikel onderzoeken Jaroslaw Kantorowicz en zijn coauteurs hoe recente politieke veranderingen het Poolse Grondwettelijk Tribunaal hebben hervormd en waarom deze ontwikkeling belangrijke inzichten biedt in hedendaagse democratische achteruitgang in Europa.

Langetermijnontwikkelingen, zoals het verouderen van de bevolking, de toename in de gemiddelde levensverwachting en de gevolgen van de recente financiële crisis, hebben bijgedragen aan de discussie rondom de houdbaarheid van het pensioenstelsel.

In 2019 hebben het Europees Parlement en de Raad de Richtlijn Preventieve Herstructurering (2019/1023) aangenomen, die voorziet in minimale harmonisatie van onder andere preventieve herstructureringskaders (preventive restructuring frameworks, 'PRF'). Dit boek biedt verdiepende analyses van de implementatie…

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Dit project onderzoekt het coördinerend vermogen van de EU in ernstige crises.

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

Promotor: Prof.dr.ir. E. Deprettere

Al jaren hét standaardwerk over politiek en openbaar bestuur in Nederland. Volledig, diepgaand en up-to-date.

This paper explores whether multilateral surveillance and policy coordination under the ES was based on a path-changing or a path-dependent mechanism

Op 12 februari promoveert Cid Swanenvleugel. Het Leiden University Centre for Linguistics feliciteert Cid!

The researchers examine the Council of the European Union's voting behaviour between 2010 and 2021 and the impact of different independent variables.

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.

Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

Promotor: Prof.dr. A. Achucarro