Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.

Announcement of a new publication by Janneke Verheijen, lecturer at the Institute of Cultural Anthropology and Development Sociology.

The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

Promotores: G.R. de Snoo, B. Sinsin, Co-Promotor: H.H. de Iongh

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

Bestudeer complexe veiligheidsvraagstukken, zoals terrorisme en cyberdreigingen, met een focus op real-life cases in Security Studies aan de Universiteit Leiden. Ontwikkel academische en professionele vaardigheden en bereid je voor op een master of carrière.

Hieronder vind je een overzicht van alle PRE-Classes die door de verschillende opleidingen van de Universiteit Leiden worden verzorgd. Bij elk onderdeel kun je een inhoudelijke beschrijving vinden en meer specifieke informatie over de eisen die aan deelname aan de betreffende Class verbonden zijn.

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

CrO2, a half-metal ferromagnet, has shown great promise for superconducting spintronics applications for nearly two decades.

Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Promotor: Prof.dr. J. Kuiper

I have studied the hot, diffuse gas around and between galaxies. Specifically, I have used the EAGLE numerical simulations of galaxy formation to predict the properties of this gas, and I have used those properties to predict specific observables: soft X-ray absorption and emission lines.

Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).

De Universiteit Leiden heeft op het moment op drie verschillende locaties Kunstmatige Intelligentie (AI) laboratoria: - Het Digital Lab, wat onderdeel is van de Humanities Hub in het Huizinga Gebouw - Het Physical Twin Lab in het Gorlaeus Gebouw - Het Archeologie Lab in the Van Steenis Gebouw

Hoe verandert generatieve AI de manier waarop we leren, communiceren en de wereld van vandaag begrijpen? Nu AI-tools deel uitmaken van het dagelijks leven, produceren ze niet alleen tekst, maar geven ze ook betekenis, beïnvloeden ze vertrouwen en hebben ze invloed op hoe we informatie vinden en delen.…

Promotor: Prof.dr. A.G.G.M. Tielens

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Promotores: H. Schiessel, G.T. Barkema

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Understanding interactions in quantum many-body systems remains one of the most profound and difficult challenges in condensed matter physics.

One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.

Galaxy intrinsic alignments induce a major astrophysical contamination to weak gravitational lensing measurements and need to be modelled and mitigated when extracting cosmological information from such measurements.

Promotor: Prof.dr. E. Deprettere

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)

Promotores: A.H. Meijer, H.P. Spaink

In this thesis integral points on affine del Pezzo surfaces are studied.