Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

The cellular metabolism of immune cells constitutes an important part of their proper function and activation. Using T cells as an example, this phenomenon is highlighted by the metabolic reprogramming that occurs in these cells upon activation.

All the data stored and processed by our computers is encoded as sequences of zeros and ones, called bits. Quantum computers offer an alternative to this traditional way of encoding and manipulating information.

Promotores: G.R. de Snoo, B. Sinsin, Co-Promotor: H.H. de Iongh

Binnen de opleiding Franse taal en cultuur richt je je op vier vakgebieden. Naast taalvaardigheid, verdiep je je in taalkunde, letterkunde en cultuurkunde. In je tweede jaar heb je de mogelijkheid om je individuele interesses te verdiepen.

This thesis probes under what conditions quantum computing presents an advantage over classical computing.

This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.

A Josephson junction is a device where a thin insulating barrier or a nanostructure is placed between two superconducting leads. Such a junction is essential to superconducting qubits that store quantum information due to its anharmonic spectrum.

Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.

Water is all around us and is vital for all aspects of life. Studying the various compounds and life forms that inhabit natural waters lets us better understand the world around us.

Research

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?

Wil je meer weten over globalisering? In de Engelstalige bachelor International Studies van Universiteit Leiden kies je een wereldregio en bestudeer je hoe regionale thema’s en gebeurtenissen in een mondiale context geplaatst kunnen worden. Hiervoor gebruik je kennis en vaardigheden uit de disciplines…

Investeer in deze tijd in het leren of verbeteren van een taal!

Bij het Academisch Talencentrum bestaat de mogelijkheid om voor praktisch elke taal een Taaltraining op Maat te volgen.

Na je bachelor kun je voor de schoolvakken Nederlands, Duits, Engels, Frans en Religie & Levensbeschouwing de tweejarige Educatieve master (120 EC) volgen.

Learning a programming language is challenging. Even one of the first –but crucial– concepts to learn, variables, is hard to grasp. Variables can represent different roles and functions within a code and need to be named appropriately to support code comprehension and debugging.

The project

Heb je een vraag over het studentenleven in Leiden, studeren aan de Universiteit Leiden of ben je op zoek naar informatie over de tweejarige masteropleiding Educatie in de Taal- en Cultuurwetenschappen? Kom direct in contact met één van onze studenten!

We weten dat het academische werk in grote lijnen onderwijs, onderzoek en dienstverlening omvat, maar hoe kunnen we, als we niet naar docenten luisteren, hen echt begrijpen en ondersteunen in hun rol om de agency van docenten te bevorderen?

In de masteropleiding Modern Languages van de Universiteit Leiden kun je je focussen op één van deze vijf moderne talen: Chinees, Engels, Frans, Duits of Italiaans.

Promotores: F.H.J. Redig, W.T.F. den Hollander

In this special edition of Information Polity there is a focus on the transparency challenges of using algorithms in government in decision-making procedures at the macro-, meso-, and micro-levels.

The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…

Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.

Houd deze pagina in de gaten voor publicaties en activiteiten in het kader van FAIR-ASSESS.

Congres/symposium, Workshop

Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Protoplanetary disks are the gas and dust environments where planetary systems form around young stars. Using observations from the Atacama Large Millimeter/submillimeter Array (ALMA) this thesis analyses the gaseous molecular reservoir, using multiple tracers to resolve the 3D structure of protoplanetary…

There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Biodiversity enables ecosystems to thrive through the synergy of functional differences among organisms. While human well-being strongly depends on biodiversity-driven ecosystem services, human actions are also at the root of current unprecedented biodiversity declines.

Promotor: Prof.dr. S.F. Portegies Zwart

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

This thesis studies operator-algebraic aspects of subproduct systems, a generalization of product systems of Hilbert spaces.

A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.

Humans share meaning through language. Over time, repeated interactions have shaped languages into forms that match our cognitive preferences, making them structured, expressive, easy to learn, and ultimately, meaningful.

Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.