Het Leiden Law blog eindigde op de tweede plek voor de 'Nationale Social Media Award voor het Onderwijs'. De awards zijn bedoeld voor baanbrekende projecten van onderwijsorganisaties waarbij sociale media centraal staan. Het Leiden Law Blog was genomineerd voor de categorie Hoger Onderwijs. De award…

Op de afgelopen SIAM applied Dynamical Systems Conference in juni, in Utha, Verenigde Staten, heeft promovendus en wiskundige Eric Siero de ‘Red Sock Award’ gewonnen.

Een internationaal onderzoeksteam metgedragsbioloog Katharina Riebel als hoofdonderzoeker en twee internationale medewerkers ontving een Human Frontier Science Program (HFSP) beurs voor het hun onderzoeksvoorstel ‘Seeing voices’: the role of multimodal cues in vocal learning.

Sylvia van Beugen heeft de Herman Musaph Literatuurprijs 2016 gewonnen voor de beste publicatie op het gebied van psychodermatologie. Haar artikel belicht het belang van lichaamsbewustzijn bij chronische huidaandoeningen, zoals psoriasis.

Afgelopen vrijdag 21 januari 2022 was de AB-jaarvergadering. Tijdens de vergadering werd de winnaar van dé annotatie van 2021 bekend gemaakt. Deze winnaars zijn Demy Jongkind en Annemarie Drahmann, beide werkzaam aan de afdeling Staats- en Bestuursrecht van de Universiteit Leiden.

Promotie

Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Promotor: G. A. van der Marel, Co-promotor: D. V. Filippov

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

We use DNA strands to stabilize few-atom silver clusters, which show unique optical and chemical properties. This thesis involves the study of these constructs for various applications.

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

Endocannabinoids are lipid messengers that modulate various physiological functions by activating the cannabinoid CB1 and CB2 receptors. While the metabolism of endocannabinoids and their action at the CB receptors is fairly well studied, the molecular mechanisms governing their release and transport…

Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

Soil biodiversity is of great importance for the maintenance of multifunctionality in terrestrial ecosystems.

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Promotor: Prof.dr. G.P. van Wezel

In the era of big data, extracting insights from complex datasets is a key challenge. This thesis demonstrates the superiority of graph-based methods over traditional clustering (e.g., k-means, DBSCAN) and outlier detection for analyzing high-dimensional and noisy data.

Galaxies in the Universe are distributed along the intricate framework of the Cosmic Web. Groups and clusters of galaxies comprise the densest regions in this network, and therefore, are excellent cosmic laboratories to study different aspects of galaxy evolution in extreme environments.

Promotor: A.P.IJzerman Co-promotor: A. Bender

The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.

Universe in a Box is erkend voor zijn educatieve waarde, door het Europese netwerk van Wetenschapseducatie (Scientix).

Russische romans hebben altijd voor ophef gezorgd. In de podcast 'Schandaal en controverse in de Russische literatuur' bespreekt universitair hoofddocent Otto Boele samen met filmmaker en journalist Kay Mastenbroek de grootste conflicten, schandalen en intriges uit tweehonderd jaar Russische literat…

Russische romans hebben altijd voor ophef gezorgd. In de podcast 'Schandaal en controverse in de Russische literatuur' bespreekt universitair hoofddocent Otto Boele samen met filmmaker en journalist Kay Mastenbroek de grootste conflicten, schandalen en intriges uit tweehonderd jaar Russische literat…

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Promotor: Prof.dr. S. Haring

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

Promotor: R.D. Gill, F. Taroni

Bart Barendregt ontwikkelt een multimodale, methodologische toolkit.

Understanding DNA repair mechanisms is essential for advancing plant biotechnology and crop improvement. This study investigates how double-strand breaks (DSBs), induced by CRISPR/Cas systems, are repaired in the model plant Arabidopsis thaliana, and how these processes influence Agrobacterium tumefaciens…

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

Promotor: Prof.dr. G.P. van Wezel

Promotores: J.C. van Houwelingen, S.A. van de Geer

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Many galaxy clusters exhibit bright diffuse radio emission that traces the underlying structure of the intracluster medium (ICM).