2,164 zoekresultaten voor “from data to insight” in de Publieke website
-
Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
-
Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
-
Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
-
Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
-
Dead body management in armed conflict: paradoxes in trying to do justice to the dead
De wereld is vol oorlog, en geen oorlog is zonder doden. Wat gebeurt er met de lichamen van dodelijke slachtoffers van oorlogsgeweld? De winnaar van de facultaire Jongbloed scriptieprijs 2015 is Welmoet Wels (Internationaal Publiek Recht). Haar scriptie Dead body management in armed conflict: paradoxes…
-
Linking soil microbial community dynamics to N2O emission after bioenergy residue amendments
Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.
-
assisted with stable-isotope labeling: exploring neuronal metabolism related to Parkinson’s disease
The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.
-
Linking simple molecules to grain evolution across planet-forming disks
Planets are formed in disks of gas and dust around young stars.
-
Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
-
The flexible listener: exploring zebra finch sensitivity to spectral and temporal sound features
Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…
-
A culture medium based approach to optimize the stratum corneum barrier of human skin equivalents
uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.
-
Persoonlijke data delen voor gezondheid
Door individuele gezondheidsgegevens te vergelijken met groepsdata, kunnen artsen advies op maat geven en kunnen patiënten leren van elkaars ervaringen. Wessel Kraaij, hoogleraar Applied Data Analytics, laat zien hoe persoonlijke data een voorspellende waarde kunnen hebben. Oratie op 24 februari.
-
Sports and data analytics: discovering the unknown known
The combination of data science and sports is a hot topic. In a talk during the opening of the Academic Year at the Faculty of Science, Professor Joost Kok explained what data analytics can teach us about sports.
-
Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
-
Design and Synthesis of Click Lipids as Tools to Study Immune Cell Metabolism
This thesis advances our understanding of lipid uptake, a vital first step in lipid metabolism, by developing innovative click chemistry-based tools to study how immune cells internalize lipids.
-
the greening Arctic: compositional and functional shifts in response to climatic changes
Promotor: E.F. Smets Co-promotor: J. Geml
-
Hunting for the fastest stars in the Milky Way
The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.
-
Harold NefsFaculteit der Sociale Wetenschappen
-
Sarah PlukaardFaculteit der Sociale Wetenschappen
-
Maarten KampertLURIS
-
Dirk van der HoevenFaculteit der Wiskunde en Natuurwetenschappen
-
Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
-
Computational aspects of class group actions and applications to post-quantum cryptography
Most of current public-key cryptography is considered insecure against attacks from sufficiently powerful quantum computers. Post-quantum cryptography studies methods to secure information resistant against such attacks. One proposal is isogeny-based cryptography, which bases its security on computational…
-
Professional learning: what teachers want to learn
Het doel van dit promotieonderzoek was te onderzoeken wat leraren zelf willen leren. De centrale onderzoeksvraag luidde: wat, hoe en waarom willen leraren leren? En hangt dit af van hun jaren leservaring en de school waarin ze werken?
-
Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
-
Student-teachers' commitment to teaching
De motivatie van studenten van lerarenopleidingen voor het beroep van leraar is afhankelijk van diverse factoren. Lerarenopleidingen kunnen de betrokkenheid van hun studenten beïnvloeden.
-
XR (Extended Reality) to learn global challenges
Ontwikkeling van effectieve VR-training voor internationaal recht van gewapende conflicten (ILAC)
-
Exploring Means to Facilitate Software Debugging
In this thesis, several aspects of software debugging from automated crash reproduction to bug report analysis and use of contracts have been studied.
-
Modulating Serine Proteases to Counteract Bleeding
Promotie
-
Sneller schaatsen dankzij data science
Veel Nederlandse schaatsers en voetballers behoren tot de absolute wereldtop. Toch kunnen ze dankzij slimme statistische analyses wellicht nóg een beetje beter worden. De Universiteit Leiden werkt er samen met Delft en Amsterdam aan.
-
EuDEco case study report (D1.3)
D1.3 describes a set of five case studies relevant in the context of the EuDEco project. Case studies are considered relevant if they are initiatives focusing on the promotion of big data and data reuse or pilots facilitating data reuse in one form or the other. The case studies were expected to allow…
-
Laura ZwepFaculteit der Wiskunde en Natuurwetenschappen
-
Big data op kleine schaal
Mirjam van Reisen pleit voor big data, opgebouwd met lokale input in ontwikkelingslanden en geschikt voor lokaal gebruik. De nieuwe hoogleraar ‘Computing for Society’ bij de faculteit Wiskunde en Natuurwetenschappen koppelt data-science aan ontwikkelingssociologie. Oratie op 10 maart.
-
Radio-interview met Barend Mons over FAIR Data
Wetenschappers moeten gemakkelijker gebruik kunnen maken van elkaars data, vindt een groep onderzoekers van verschillende universiteiten. Daarvoor ontwikkelden ze de FAIR-principes. BNR Nieuwsradio sprak erover met initiatiefnemer Barend Mons, hoogleraar Biosemantiek aan het Leids Universitair Medisch…
-
The mixed Ax-Lindemann theorem and its applications to the Zilber-Pink conjecture
Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)
-
The potential of multi-scale EE-MRIO to support sustainable development policies in Indonesia
Global Environmental Extensions Multi-Regional Input-Output (EE-MRIO) analysis is often used to analyze how changes in global and national demand for products lead to socioeconomic and environmental impacts at the national level.
-
Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
-
Masterstudenten Data Science presenteren oplossingen aan Rijk en Tweede Kamer
Op 1 november 2019 presenteerden internationale masterstudenten Data Science van de Universiteit Leiden de uitwerking van hun dataconcepten aan hoge functionarissen van de Tweede Kamer en het Rijks I-Ecosysteem. Met de presentatie rondden ze dit deel van de mastercursus Data Science succesvol af.
-
Door data te integreren kunnen we onze kennis vergroten
In wetenschappelijk onderzoek worden iedere dag enorme hoeveelheden data geproduceerd. Die zouden we nog veel meer kunnen benutten dan we op dit moment doen, zegt Katy Wolstencroft, assistent-professor in (bio)informatica. Maar dan moeten we de data wel beter beheren en integreren.
-
Een juridische schatkist aan data
Data science biedt ongekende mogelijkheden voor juridisch onderzoek, zeggen Simone van der Hof en Bart Custers van eLaw. Maar we moeten ook de ongewenste bijwerkingen van big data - zoals etnisch profileren - in de gaten houden.
-
Big data kan niet zonder statistiek
Data science en statistiek zijn nauw met elkaar verbonden, zegt Spinozawinnaar en hoogleraar Stochastiek Aad van der Vaart. We praten met hem over de big data-hype, genoomonderzoek en samenwerking met andere vakgebieden. ‘Statistiek helpt overal waar data niet perfect is.’
-
Catching cereal killers: A multi-omics approach to disentangle yeast- Fusarium interactions in the phyllosphere
The overarching goal of this PhD thesis is to investigate the taxonomic and functional diversity of yeasts in the wheat phyllosphere and their interactions with the mycotoxigenic fungal pathogen Fusarium graminearum.
-
Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
-
Gabriel Spautz VieiraFaculteit der Archeologie
-
Leidse datawetenschappers kijken naar de toekomst van data in sport
Waar staan we over tien jaar? Hoe ziet de Nederlandse sport er dan uit? Hoeveel records hebben we dan verpletterd? Weten we dan beter hoe we blessures kunnen voorkomen? En hoe heeft sportdata, die de laatste jaren toch een steeds centralere rol heeft gekregen, ons hierbij kunnen helpen?
-
Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
-
To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
-
Species Literacy: The perception and cultural portrayal of animals
In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.
-
Minder kans op virusuitbraken dankzij data science
Data science is van groot belang bij het voorkomen van toekomstige uitbraken van virusziekten, aldus informaticus Aske Plaat. Hij aanvaardt op 13 april zijn benoeming als hoogleraar Data Science met zijn oratie ‘Data Science and Ebola.’
-
transient reductions in the speed of sound of the inflaton in cosmological data, and other topics
Promotor: Prof.dr. A. Achucarro