671 zoekresultaten voor “applied linguistics” in de Publieke website
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Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
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Stock-driven Scenarios on Global Material Demand
The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…
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Systemic Accountability of the European Border and Coast Guard
Op 11 november 2021 verdedigde Mariana Gkliati het proefschrift 'Systemic Accountability of the European Border and Coast Guard'. Het promotieonderzoek is begeleid door promotoren prof.dr. P. Rodrigues en prof.dr. L. Besselink (UvA).
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On the Emergence of the Energy Transition
The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Green defense against thrips- Exploring natural products for early management of western flower thrips
As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).
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On metrics and models for multiplex networks
In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Comparative biology of common and grey seals along the Dutch coast
What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?
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Towards photo-CIDNP MAS NMR as a generally applicable enhancement method
Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Combining monitoring with run-time assertion checking
Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Does it still hurt?
The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.
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Photoinduced processes in dye-sensitized photoanodes under the spotlight: a multiscale in silico investigation
With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Ecology of the Ethiopian wolf (Canis simensis Rüppell 1835) in a changing landscape: Human carnivore interactions in Afroalpine ecosystems of
Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Multi-objective mixed-integer evolutionary algorithms for building spatial design
Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.
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Voorlichtingsactiviteiten
Kom naar onze online en oncampus events om ons beter te leren kennen!
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Towards a Sustainable and Circular Metals Economy
In-use stocks of products can be considered as intermediaries between human needs and the physical world.
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Corporate venture management in SMEs: evidence from the German IT consulting industry
Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)
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The evolution of chemical diversity in plants : pyrrolizidine alkaloids and cytochrome P450s in Jacobaea
Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.
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Instituut voor Metajuridica
De rechtswetenschap is een verzamelnaam voor de 'juridica' en 'metajuridica'.
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Software developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Jos Schaeken in NRC over teksten op oude Russische stukken berkenbast
In de Russische stad Novgorod zijn bij opgravingen strookjes berkenbast gevonden. Op de strookjes zijn korte boodschappen ingekrast. Jos Schaeken, hoogleraar Slavische en Baltische talen, vertelt in het NRC meer over deze bijzondere vondsten.
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Stemmen op berkenbast
Persoonlijke briefjes uit middeleeuws Rusland? We kennen wel veel officiële en kerkelijke documenten, maar de vondsten van stukjes beschreven berkenbast uit Novgorod geven op een unieke wijze inzicht in hoe 'gewone' mensen dagelijks met elkaar communiceerden.
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Over ATC
Het Academisch Talencentrum is onderdeel van het Leiden University Centre for Linguistics (LUCL). Studenten en medewerkers kunnen bij het Talencentrum taal- en cultuurcursussen volgen.
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Kwaliteitsborging ATC
De volgende kwaliteitslabels en lidmaatschappen bevestigen de hoge standaard die ATC hanteert.
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Studentenleven
Leiden is een echte studentenstad en heeft alles in huis om van jouw studententijd een onvergetelijke tijd te maken.
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Vervolgopleidingen
Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Met een masterdiploma op zak heb je meer kans op een baan op academisch niveau. Na afronding krijg je de titel Master of Arts (MA).
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Hello, who is this? The relationship between linguistic and speaker- dependent information in the acoustics of consonants
Promotie
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An Introduction to the Arabic Language History and Origins
Alumni-activiteit, Lunch webinar
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PDI-SSH-subsidie voor AI-project Anne Meuwese
Met haar project WetSuite wil Meuwese AI-technieken die gebruikt kunnen worden om juridische overheidsdocumenten te analyseren toegankelijk maken voor een brede groep onderzoekers.
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Nederlanders moeten stoppen met ‘beleefd’ omschakelen naar Engels
Bedreigde talen kunnen voortleven als ze goed worden geleerd aan nieuwe sprekers, zoals mensen met een migratieachtergrond. Dit stelt bijzonder hoogleraar Felix Ameka in zijn oratie op 30 september. Nederlanders kunnen daaraan bijdragen door zich minder ‘beleefd’ op te stellen richting mensen van wie…
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Eerste grammatica van het Hamar onthult uniek taalsysteem
Linguïst Sara Petrollino schreef de eerste uitgebreide grammatica van het Hamar, een taal gesproken in Zuidwest-Ethiopië met unieke eigenschappen. Promotie op 10 november.
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Eregalerij 2023
In 2023 hebben medewerkers en studenten van de Universiteit Leiden veel mooie prijzen gewonnen en belangrijke onderzoekssubsidies binnengehaald.
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Taalwetenschap (BA)
Elke dag gebruik je taal: om te lezen, schrijven, te communiceren. Maar hoe heb je als kind eigenlijk je eigen taal geleerd, en hoe leer je nu nieuwe talen? Taalwetenschap heeft het antwoord. Bij de bachelor Taalwetenschap aan de Universiteit Leiden heb je de kans om deze discipline in haar volle breedte…
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Chainet - European network on chain analysis for environmental decision support
Analytical tools for environmental design and management in a systems perspective. The combined use of analytical tools.
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Vervolgopleidingen
Volg een Masteropleiding na het behalen van je Bachelor Pedagogische Wetenschappen.
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Assistant Professor Methodology & Statistics
Sociale Wetenschappen, Psychologie
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Juridische oordeelsvorming in het aansprakelijkheidsrecht en financieel toezicht
Het vertrekpunt van dit onderzoek is de bevinding dat het menselijk brein vatbaar is voor allerlei denkfouten en vooringenomenheden (biases), die onze percepties kleuren en onze redenaties beïnvloeden, zonder dat we dit bewust doorhebben. Integendeel, mensen hebben veelal het gevoel dat zij slechts…
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China’s industrial carbon emissions: Historical drivers at the regional and sectoral levels and projections in light of policy targets
Has the industrial sector in China effectively been decarbonizing in recent years, across different regions and subsectors, and is it plausible that it will reduce its CO2 emissions in conformity with national and internationally pledged emission goals?
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EPCEM 2001: Differences in the authorization process of GMOs in the EU and the USA
This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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C-SCAPE - Sandy strategies for sustainable coastal climate change adaptation
What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?