Op 29 June 2017 heeft Carl Mair zijn proefschrift “Taking Technological Infrastructure Seriously” verdedigd. De supervisors zijn prof.mr. A. Schmidt en prof.dr.mr. G.J. Zwenne.

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

Identification of the products or product groups that have the greatest environmental impact from a life-cycle perspective using environmentally extended input-output analysis.

In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.

In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

Promotor: Prof.dr. T. Hankemeier

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

What impact does a mid-season wildfire have on grassland invertebrates?

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

Promotor: Prof.dr. B.R. Katzy

An interdisciplinary collection of the best international scholarship on Muslim youth.

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

Promotor: Roeland M.H. Merks

Promotor: Prof.dr. E. F. van Dishoeck

Promotor: K.J. Batenburg

The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Promotor: S.M. Verduyn Lunel

A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Promotor: Prof.dr. S.F. Portegies Zwart

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…

1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

The applications of studying the early development of insects range from agriculture to material science.

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…