Universiteit Leiden

nl en

Lecture

CANCELED This Week's Discoveries | 30 June 2020

Date
Tuesday 30 June 2020
Time
Serie
This Week's Discoveries
Address
Kaltura Live Room

Chemical similarity to identify substances of potential concern

Speaker
Pim Wassenaar (CML)
Pim is a PhD candidate at the Institute for Environmental Sciences (CML) and also works at the Dutch National Institute for Public Health and the Environment (RIVM) where he works as an risk assessor of chemical substances. His research focusses on the identification of chemicals of potential toxicology concern for regulatory follow-up.    

Abstract
Worldwide, more than 350,000 chemicals and chemical mixtures are registered for production and use. Due to this large amount of substances, screening and prioritization are essential in order to focus chemical evaluation on those chemicals of highest concern. We recently developed a chemical similarity methodology that assesses whether a new chemical is structurally similar to a known chemical of concern. A high resemblance in chemical structure might be an indication of comparable effects (‘similar property principle’), and therefore could be a trigger for further evaluation. The structural similarity model shows great potential for screening and prioritization purposes, and could further contribute to the transition from substance-by-substance assessments to group assessment approaches.

Read more about the lecture series This Week's Discoveries

This website uses cookies.