Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…

The Netherlands Organisation for Scientific Research has awarded a grant of 750,000 euros to the 'Visualising the Unknown in 17th-century Science and Society' project. Researchers will reconstruct how seventeenth-century scientists recorded and shared their groundbreaking microscopic discoveries. We…

Education

Underwater noise from seismic surveys affects the behaviour of Atlantic cod. These are the results of research by Leiden biologists in collaboration with colleagues from Belgium. During such surveys the fish are less active than usual and their circadian rhythm is disrupted; soon after exposure they…

Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a crucial role in future research and eventually in addressing the global plastic crisis. The study was published in Nature Communications.

Sunshine, ice cream, coffee, and plenty of good vibes. Once again, students and staff made the most of the We are Science Week. Relive some of the highlights with our photo report!

About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…

Should we be growing rice and building materials instead of grass for cows? From invasive crayfish to cultural heritage and groundwater levels: ten graduating students explored the future of the Groene Hart, the rural region just outside the cities of Delft, Rotterdam and Leiden where they study.

Matthias Flór receives the KHMW Graduation Prize in Theoretical Physics for his master's thesis. His research on exotic superconductors at Leiden University and TU Delft struck a chord with the jury. The jury unanimously chose to award Flór noting that ‘he demonstrated impressive technical abilities…

Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.

More than 1.3 million people worldwide die of tuberculosis (TB) each year, making research on its prevention and control essential. Researchers from various disciplines in Leiden are studying TB. A symposium on 24 March will highlight different activities in the hope of boosting nationwide collabora…

Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…

Biologist Nataliia Machushynets felt like she was ‘looking for a needle in a haystack’, trying to find new antibiotics to help solve the problem of resistance. During her PhD research, she did find what she was looking for, in the soil beneath our feet.

The antibiotic EVG7, developed in Leiden, has proven capable of fighting the dangerous gut bacterium C. difficile with only a minimal dose. What’s more, the bacterium is far less likely to return, a major issue with existing antibiotics. The research was published in Nature Communications.

Sam Hundersmark is taking a Master's in Population Health Management at Leiden University. Because Leiden University is part of the Una Europa alliance, Sam was able to join the 2023 edition of Una Europa’s One Health Summer School.

Two research groups involving Leiden University have been awarded a major European grant, the ERC Synergy Grant. This for research on the development of membranes that can clean water and purify medical drugs and research on the biological clock in certain bacteria.

In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…

Collaborating and learning from other fields – that is what bioinformatician Hannah Augustijn enjoys most about doing research. During her PhD at Leiden University, she developed new ways to search within bacteria for the antibiotics of the future.

A CT scanner to treat eye cancer, energy-efficient software for the future and a test to identify male chick eggs. Three projects by researchers from Leiden University are to receive funding from research funder NWO’s Open Technology programme, to which the business sector also contributes.

Genetically modified organisms (GMOs) could be useful allies in the fight against critical environmental problems. Could because the use of GMOs is strictly regulated at the moment. A Leiden student team is now trying to make these GMOs safer with the aid of an ingenious lock.

Conference

Lecture, Tuesday Talks: Science Insights

Lecture, Pint of Science

Lecture

He came to the Netherlands for three months and never left. Marcello Bonsangue is the new scientific director of the Leiden Institute of Advanced Computer Science (LIACS) since January this year. 'I think it is important to be there for the people of our institute. My door is always open.'

A microscope with incredible sharpness that leaves samples unharmed – Guido Stam helped develop one. During his PhD research, he combined light and electrons to study biological samples. ‘We can now measure things that simply weren’t possible before.’

Meeting new people, exploring other disciplines and growing academically, professionally and personally. The Honours College makes it all possible. Three honours students tell why they do something extra during their bachelor.

With a single sample of water or soil, researches can analyse the DNA of everything that is living in that environment. During her research, PhD candidate Beilun Zhao discovered a way to analyse not only the kind of species, but also the age of the species in a water sample. The method showed its first…

Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…

Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.

Tuesday was the opening session of the LDE Bachelor Honours Programme Sustainability. Lecturers introduced themselves, students got to know each other and it was revealed what they will do to contribute to a more sustainable world in the coming months. "I immediately feel like getting started," said…

Studying as an asylum seeker without a residence permit. Every year, student initiative IncLUsion enables dozens of asylum seekers to take several courses at Leiden University. ‘Education has given me a lot of support.’

Annually, the Dutch Palynologische Kring invites nominations for the Florschütz Award for best MSc thesis in Palynology and Palaeobotany. This year, the thesis of Archaeology alumna Oda Nuij was deemed to be the best one. Oda was surprised to hear she won, since she was not sure that the thesis would…

Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…

She walked into the Sylvius building as a wide-eyed twenty-something in 1984, and next year, she’ll be leaving us as a soon-to-be retiree in her sixties. Ine Tijdens (66) reflects on more than four decades at LACDR. ‘One year, I got a little whip for Sinterklaas. That says something about my persona…

On Saturday 16 April, secondary school pupils will once again have a chance to sink their teeth into the hardest language-related questions during the final of the Linguistics Olympiad. Professor Sasha Lubotsky and PhD student Cid Swanenvleugel are both former Olympiad winners. Now they are involved…

It’s Saturday and electric minibuses ride back and forth bringing prospective students to Leiden University’s various faculties. They want to see for themselves whether that interesting-looking programme will suit them.

At science festival 'Over de kop', surprising brain facts alternate with confronting stories from the operating room. Researchers explain why our brains love beans and why you should never ride a racing bike without a helmet.

Two statues of gorillas abducting women: they were what led PhD candidate Dick van Broekhuizen to write a new type of history of nineteenth-century sculpture. ‘If you view nineteenth-century art history from a less narrow perspective, the narrative changes completely.’ PhD ceremony on 21 June.

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

Donororganen zijn er nooit genoeg. De organen die wel beschikbaar zijn, moeten vliegensvlug getransplanteerd worden. De geneeskunde zet daarom volop in op het langer goedhouden van organen. Marlon de Haan (24) onderzoekt hoe je nieren buiten het lichaam in leven kunt houden.

After two years in the Faculty Board, Student Assessor Zoë van Litsenburg makes room for a successor per September 1, 2022. Let’s meet the new Student Assessor Imen el Idrissi. ‘I want to focus on the communication between the Faculty and the students.’

Anne Veens is on a mission. She wants secondary school students to get acquainted with anthropology, and think about the value it can have in the development and implementation of policy. To achieve this, she has developed a teaching package. Last July, she successfully ran the first pilot. 'Most pupils…

Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…

The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance. ‘The idea was to tweak the original antibiotic and create a next-generation drug’, says Nathaniel Martin, professor…

The Bachelor Honours Class 'Homo Ludens: Why We Play' combines games, theory, and practice. Students dive into all aspects of humanity in which games play a part and discuss them, both on a theoretical an experiential level: 'Occasionally, you touch upon what play is, but then it eludes you.'

Predicting the collective behaviour of systems, like a large group of people electing one of the parties, is no easy task. But there’s a theory that scientists have been using for decades to do just that: the theory of Gibbs measures. Last week, mathematician Mirmukhsin Makhmudov earned his PhD for…

The Houthis are attacking ships in the Red Sea. Rerouting via South Africa is expensive, whereas the Arctic route only takes a week. Once a no-go zone, this route might be a more realistic option. Mind the nuclear submarines, though…