Elizabeth Stuart is one the most misrepresented – and underestimated – figures of the seventeenth century. Daughter of James VI & I, she was married to Frederick V, Elector Palatine in 1613 – they were crowned King and Queen of Bohemia in 1619, only to be deposed and exiled to the Dutch Republic in…

The agency and impact of Greek statuary in the city of Rome

Shining a light on the nefarious netherworlds of espionage, this is the first book to concentrate on the actual techniques and technologies used by early modern spies —from ciphers to counterfeiting, invisible inks to assassination

The American Association of Pharmaceutical Scientists (AAPS) has been pleased to announce Dr. Elizabeth de Lange as a recipient of the 2013 AAPS Fellows Award at the 2013 AAPS Annual Meeting and Exposition in San Antonio.

This paper describes the development process of voting behavior in Chile; particularly the relationship between the class voting theory and the theory of cultural post-materialist vote is investigated. This research deals with Chile as a case study, a developing country with a relatively stable democracy…

PhD defence

Professor of Predictive Pharmacology Elizabeth de Lange has received an Honorary Doctorate from the Faculty of Pharmacy of Uppsala University. She will be honoured during the Uppsala Winter Conferment Ceremony on 31 January 2020.

Understanding others’ emotional behavior is essential for navigating daily social life. But how is such an understanding achieved? The eye-tracking study by Yung-Ting Tsou and colleagues shows that children with hearing loss adopt a unique visual strategy that makes uses of explicit visual information…

The Hague Diplomacy Podcast aims at bringing the themes of the journal's research off the page, and onto the discussion table. Each episode will feature a guest who will share their insights and personal experience within their practice of or research on diplomacy. Available via SoundCloud, Apple Podcasts…

On Wednesday 3 July 2024 Renata Schiavo successfully defended a doctoral thesis and graduated.

Dutch coalition parties VVD and CDA want to tighten asylum policy and have launched a plan to grant two types of statuses to refugees. They also intend to partially restrict the right to family reunification. However, this plan is facing strong opposition. With the proposal, the government can expect…

Almost 81 years after his famous protest speech against the German occupation, Leiden professor Rudolph Pabus Cleveringa will be remembered in his Groningen birthplace of Appingedam. A statue of him will be unveiled there on 12 November amid various other activities.

Dr Nadine Akkerman, lecturer in Early Modern Literature and postdoctoral researcher in Leiden, has written a new book to accompany the exhibition on Elizabeth Stuart and Amalia von Solms at the Historical Museum of The Hague. ‘They were like goddesses, constantly trying to upstage one another,’ says…

Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh

UNESCO has recognized a large collection of handwritten letters and the archive of Raden Ajeng Kartini (1879-1904) as documentary world heritage. Kartini opposed gender inequality in feudal Javanese society, including forced marriages, polygamy and lack of education for women.

Meet the people of the Resilience Center

Do you have any questions about the bachelor's programme International Studies? Don't hesitate to contact us!

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.

This new volume, published 19 November 2020, - within the series 'Intersections' -, explores the concept of magnificence as a social construction in seventeenth-century Europe. Although this period is often described as the ‘Age of Magnificence’, thus far no attempts have been made to investigate how…

In Migration and Membership Regimes editors Ulbe Bosma, Gijs Kessler and Leo Lucassen bring together ten essays in an analytical framework which looks beyond the Transatlantic migration of the nineteenth and twentieth centuries in a deliberate attempt to incorporate the experience of earlier periods…

Another research line is the development of a spatial CNS drug distribution model, by ultimately including the 3-dimensional anatomical organization of the CNS.

The aim of this research area is to be able to predict human drug response on the basis of mathematical models that are developed using preclinical experiments and prior knowledge.

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

Prof. Elizabeth de Lange is concerned with the allocation of resources for the conduct of science towards the goal of best serving the public interest. Also, while she underscores that there is still the need for using animals in drug research, she is concerned about this use, and advocates the use…

Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).

Uniting an international consortium of scholars, the Skandapurāṇa Project comprises a team of researchers working in fields across the Humanities. We are creating a critical edition of a foundational work of purāṇic literature and, in doing so, tracing the dynamics of a textual tradition to better understand…

The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…

You may know it by the umbrella term 'citizen science'. You may also use terms such as volunteer mapping, patient co-researcher, or even community engaged learning to describe participatory practices in your research or teaching. No matter what you call it, there’s plenty going on when it comes to this…

The staff of the Master of Laws: Advanced Studies in International Children’s Rights is extremely proud.

The research project examines the site-specific event within the field of installation art and choreographic practices.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

How can the importance of the image in late medieval spirituality be understood in the context of the love mysticism inspired by the imagery of the Song of Songs?

The Institute of Cultural Anthropology and Development Sociology is one of five research institutes of the Faculty of Social and Behavioural Sciences. The Institute is dedicated to high-quality, interdisciplinary education and research concerning culture and development.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.