372 search results for “parkinson s disease” in the Student website
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Marit RuitenbergSocial & Behavioural Sciences
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Elizabeth (Liesbeth) de LangeFaculty of Science
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Can Parkinson's be stopped by unravelling protein fibres? Anne Wentink finds out with a Vidi grant from NWO
In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…
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How cells determine the fate of proteins (and can we do it too?)
Cells in our bodies are often threatened by errors in our own proteins. The FLOW consortium, comprising scientists from various institutions including Leiden, is poised to meticulously map out for the first time how cells control proteins, correcting or removing faulty ones. This endeavour holds promise…
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Jolanda SnelSocial & Behavioural Sciences
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Bram SlütterFaculty of Science
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Hans AertsFaculty of Science
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S. HoutermanFaculty of Science
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ESOF session on vaccines: ‘Infectious diseases know no borders’
How can Europe lead the way in vaccine development that is fast and for all? To answer this pressing question, Professor of Vaccinology Meta Roestenberg is holding a panel session on 14 July at the EuroScience Open Forum in Leiden.
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Katja CardolSocial & Behavioural Sciences
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Tim KoppertSocial & Behavioural Sciences
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S.C.A. Lefebvre
Social & Behavioural Sciences
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S. ValdezFaculty of Humanities
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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Daan van der VlietFaculty of Science
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Margo DonaFaculty of Science
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Willem FibbeFaculteit Geneeskunde
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Patrick van Hage
Faculty of Science
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Tuomas AiveloFaculty of Science
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Jordy van der BeekFaculty of Science
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Joey ZuijderveltFaculty of Science
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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Preventing heart attacks by earlier detection of cardiovascular disease
In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…
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O.S.A.A. HeikalFaculty of Science
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Annemarie MeijerFaculty of Science
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Jyothi ThrivikramanFaculty of Governance and Global Affairs
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Flooded polder helps fight mosquito-borne diseases
One and a half hectares of polder, a large volume of water, and a group of curious researchers from various universities and scientific backgrounds led by ecologist Maarten Schrama. These are the ingredients needed to answer the question: how do water retention areas affect nature, animals, and our…
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Andrew GawthorpeFaculty of Humanities
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Paul HooykaasFaculty of Science
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Veronique de GuchtSocial & Behavioural Sciences
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Outbreak of an infectious disease? Mathematics helps in making quick, informed decisions
A job thanks to COVID—something not many people can claim. But PhD candidate Vera Arntzen can. Over the past four years, she has mapped two crucial characteristics of SARS-CoV-2 infections. Thanks to her research, experts can now make well-informed decisions on matters like quarantine duration, which…
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Better treatment of skin diseases thanks to NWA grant of 11.7 million euros
Patients with skin diseases such as eczema and psoriasis, sometimes spend a lifetime searching for the right medication. To help these patients faster and better, scientists across the country are joining forces. The Next Generation ImmunoDermatology (NGID) project, with LACDR professor Robert Rissmann…
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Maia CasnaFaculty of Archaeology
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Roeland MerksFaculty of Science
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Stiffness and viscosity of cells differ in cancer and other diseases
During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.
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Lies PunselieFaculty of Law
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From liquid to solid: revolutionary technique uncovers disease-related changes in tiny droplets within our cells
Understanding the behaviour of tiny droplets in our cells could aid the search for new treatments. A team of Leiden researchers has developed a groundbreaking method to study how these droplets transition from liquid to solid. This change plays a role in various diseases, including neurodegenerative…
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Frits RosendaalFaculteit Geneeskunde
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Maria YazdanbakhshFaculteit Geneeskunde
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Coen van HasseltFaculty of Science
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Lotte NagelhoutFaculty of Archaeology
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Afrooz Kaviani JohnsonFaculty of Law
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Frank SchaftenaarFaculty of Science
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Vivian Kraaij
Social & Behavioural Sciences
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Apollonia BolscherFaculty of Law
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Investigating inflammation: new leads for treating atherosclerosis
How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…
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Greater understanding of specialised cell could prevent strokes
Ilze Bot wants to reduce the prevalence of cardiovascular diseases. Her research focuses on mast cells, which protect us from infections but can also make us ill.
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Marnix MedemaFaculty of Science
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Suzy DuivenvoordeFaculty of Law