621 search results for “covid-19 vaccine” in the Public website
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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Hirschman, Accountability in Global Governance
Political Scientist Gisela Hirschmann (Leiden University) asks how international organisations can be compelled to comply with respect human rights. She finds that this is done through ‘pluralist accountability’: external third parties such as courts, NGOs, or regional organisations holding international…
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Development of nanoparticulate adjuvants based on aluminium salts
The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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Bio Science Park generates thousands of jobs and millions of euros for the Leiden region
The Leiden Bio Science Park (LBSP) is very important not only for the city of Leiden but also for the Leiden region and the Netherlands as a whole. This is the finding of an investigation conducted by the Leiden-Leiderdorp Audit Committee. The large-scale development of the LBSP in recent years has…
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Our man in Jakarta keeps the institute running from Venlo
The COVID-19 pandemic forced many staff of Leiden institutes abroad to leave their posts in a hurry. How is the KITLV Jakarta team doing now? Director Marrik Bellen talks about the turbulent times for this Leiden institute and its staff. And can we learn anything from the Indonesian approach?
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Immunotherapy to limit atherosclerosis
Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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Therapeutic Immunomodulation
The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.
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Formulation of Peptide-Based Cancer Vaccines
PhD defence
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Immunity, Infection and Tolerance
Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…
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Using health data for scientific research isn’t that simple
While health data is essential for scientific research, that data also needs to be protected. In her doctoral thesis, Irith Kist found a balance between protecting the individual and exchanging health data.
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Conflict resolution by internet platforms
The Covid-19 'infodemic' and conflict resolution by internet platforms.
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Innovation in treatment and care
Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…
- Health Diplomacy
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Ovalbumin coated pH-sensitive microneedle arrays effectively induce ovalbumin-specific antibody and T-cell responses in mice
The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…
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Gaining control of lipid-based nanomedicine by understanding the nano-bio interface
Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…
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Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
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Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci
Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…
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A Harmonised EAC COVID Pass to Re-Kindle Intra-Regional Trade
COVID-19 poses a significant barrier to intra-regional trade within the EAC, causing interminable hold-ups at the internal borders.
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Anne Meuwese and Bart Custers in Trouw on Covid apps
The more people are vaccinated, the more society can slowly reopen. Technological developments, like the Covid passport and other apps, can play a role in this. Artificial Intelligence could help greatly in developing the vaccine passport and the Covid-19 exposure notification app, Anne Meuwese and…
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Anne Meuwese and Bart Custers in Trouw on Covid apps
The more people are vaccinated, the more society can slowly reopen. Technological developments, like the Covid passport and other apps, can play a role in this. Artificial Intelligence could help greatly in developing the vaccine passport and the Covid-19 exposure notification app, Anne Meuwese and…
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Biologics Formulation
A major challenge in the formulation of biopharmaceuticals is to overcome their inherent instability during production, storage, transportation, handling and administration. We are studying underlying mechanisms of degradation of biopharmaceuticals (including therapeutic proteins, vaccines and advanced…
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Antibody Glycomics Signatures of SARS-CoV-2 Infection and Vaccination
PhD defence
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Learning the Right Lessons for the Next Pandemic
This report highlights the huge potential of public inquiries to ensure that lessons are learned from COVID-19 to help the UK prepare for a future pandemic.
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Targeting of antigen-presenting cells with mannosylated conjugates
This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Vaccination: intradermal administration, duration of protection, and compromised immunit
PhD defence
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Monitoring the immune responses to vaccination and infection
PhD defence
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Research
Research at the BIOSYN group is comprised of the following research themes:
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COMET. Human Subject Research and Medical Ethics in Colonial Southeast Asia
Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.
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Voices of Young Academics
We as Young Academy Leiden are continuously educating ourselves and are listening to the voices coming from our own university, especially the young academics.
- Fake News/Disinformation
- Populism
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Immunity, Infection and Tolerance
The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.
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Formulation of biopharmaceuticals
Formulation of biopharmaceuticals
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Immunotherapy to limit atherosclerosis-projects
For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.
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Fall of Misinformation Series: Ionica Smeets
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
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Fall of Misinformation Series: Suzan Verberne
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
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Zwitterionic oligosaccharides: charging the immune system
How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?
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Block 4
In the overview below you can find the LUC Newsletters that were send out during block 4 in semester 2 of academic year 2019 - 2020.
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Mirjam Sombroek appointed member of Health Council
By Royal Decree, Mirjam Sombroek van Doorm was appointed as a member of the Health Council of the Netherlands as of 1 January 2024. She has joined the standing committee for Ethics and Law as well as the temporary Brain Injury through Sports Committee. The Health Council of the Netherlands is an independent…
- Blog Posts Archive
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Bolivia at the Crossroads: Politics, Economy, and Environment in a Time of Crisis
As Bolivia reels from the collapse of the government in November 2019, a wave of social protests, and now the impact of Covid-19, this book asks: where next for Bolivia?
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The Future of Multilateralism: Global Cooperation and International Organizations
The Future of Multilateralism addresses current challenges and future perspectives of international and regional organizations. It aims to uncover how stable the foundations of global cooperation really are, particularly in the light of the latest unilateral and protectionist practices of international…
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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REACT Study
The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…
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Venue
Due to the Covid-19 pandemic SIP 2021 will be held online.