This Element considers Kant's conception of self-control and the role it plays in his moral philosophy. It offers a detailed interpretation of the different terms used by Kant to explain the phenomenon of moral self-control, such as 'autocracy' and 'inner freedom'.

Regulating Relations: Controlling Sex and Marriage

How does task context affect children’s word productions?

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

This article illustrates how the term 'dual use' has become associated with a broader dichotomy between ‘legitimate’ and ‘illegitimate’ purposes.

Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.

In a modernist interpretation of migration controls, nation states play a major role. This book challenges this interpretation by showing that comprehensive migration checks and permanent border controls appeared much earlier, in early modern dynastic states and empires, and predated nation states by…

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

On the 12th of October, Fatemeh Tabassi Mofrad successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Fatemeh on this achievement!

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

What is the role of the noradrenergic system in human cognition?

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

William Lippert investigates the effect of delegation to an agreement executor on success of conventional arms control agreements in Europe.

What made the early Islamic empire so successful and have we missed the story by neglecting crucial evidence? The 7th-century Arab conquests changed the socio-political configurations in the Mediterranean and Eurasia forever. Yet we do not really know how the Arabs managed to gain dominance of this…

How do humans control their thoughts and actions, and what can high-field brain scanning reveal about the underlying processes?

On 20 March 2019, Tim Dekkers defended his thesis 'Mobility, Control and Technology in Border Areas: Discretion and Decision-making in the Information Age'. The doctoral research was supervised by Prof. dr. J.P. van der Leun en Prof. dr. M.A.H. van der Woude.

Up to 45% of patients with Parkinson's disease experience impulse control disorders, characterised by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development…

Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

Jaroslaw Kantorowicz and Rok Spruk examine the contribution of institutional reforms to economic growth.

Sorghum (Sorghum bicolor) is a major cereal crop that millions of subsistence farmers in Sub-Saharan Africa (SSA) rely on. However, the scourging impact of the root parasitic weed Striga (Striga hermonthica, a.k.a. “witch-weed”) has remained a major constraint hampering the productivity of sorghum in…

This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

Intensive public debates have erupted about integration of immigrants in Europe. The influx of refugees from the middle east during the summer and autumn of 2015, the increasing visibility of immigrants throughout European societies, but also the widely publicized occurrences on New Year’s eve in Cologne…

To argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection.

At present, the cabinet still maintains that all provinces are motivated to cooperate with the sensitive issue of the nitrogen strategy. However, there are major concerns that the political landscape will look very different once the elections for the Provincial Councils on 15 March have been held.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Governments in parliamentary democracies have limited time in office to fulfill their policy agendas. So, how do they optimise the timing of legislative bills to assure their passage and avoid lengthy parliamentary scrutiny? This question is especially puzzling under coalition governments, in which…

Although it is often assumed that the stereochemistry in Ugi multicomponent reactions is determined in the final Mumm rearrangement step, experimental and computational evidence that Ugi reactions on hydroxylated pyrrolines proceed under kinetic control is reported.

This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

Following her appointment to the Chair in EU External Economic Law earlier this year, Prof. dr. Freya Baetens addressed the academic community of Leiden University with her inaugural lecture on 27 October 2023. In a highly topical lecture, Prof. Baetens examined the EU’s Anti-Coercion Instrument (AC…

China is a one-party regime, yet elections are held for the local congresses. PhD candidate Wang Zhongyuan investigated how the Communist Party uses this democratic instrument to strengthen the authoritarian regime. PhD defence 31 January.

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

In this article, Gerrit Dijkstra and Jos Raadschelders from the Institute of Public Administration, argue that Bosnia-Herzegovina survives so far on the basis of negative legitimacy.

Promotor: Prof.dr. S. Haring

PURPOSE: The aim of the study was to develop a cheap and fast method to produce hollow microneedles and an applicator for injecting vaccines into the skin at a pre-defined depth and test the applicability of the system for dermal polio vaccination.

We found that, next to the effectiveness of the intervention, it’s also very likely that the intervention is cost-effective compared to attention only.

Matthew Hoye argues for a regulatory analytical perspective to look at the sanctioning of Afghanistan.

On 12 September 2019, Michiel Rhoen defended his thesis 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. The doctoral research was supervised by Prof. G.J. Zwenne and Prof.…

The STAP study examines the cost-effectiveness of Written Exposure Therapy (WET) for post-traumatic stress disorder (PTSD) symptoms in primary care settings.