Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

In november 2023 is Anne Fleur van Veenstra, wetenschappelijk directeur van TNO Vector, benoemd tot bijzonder hoogleraar ‘Governance van data en algoritmen voor stedelijk beleid’.

A new study published in Nature provides the most detailed picture to date of Neandertal diversity in western Europe shortly before their extinction.

Wil jij bijdragen aan vitaliteit en gezondheid in Leiden Noord? Doe dan een Master onderzoek rond thema's als eenzaamheid, gezondheid en leefstijl of gezond gedrag in de publieke ruimte. In samenwerking met Leren met de Stad en Incluzio, voer jij jouw onderzoek uit op de locatie van Leren met de Stad…

Following the announcement of revised financial projections at the start of the academic year, the Faculty Board was keen to engage in dialogue with the wider faculty. Through information sessions held at all institutes, at the Faculty Office and in The Hague, we met with many of our staff members to…

Sustainable biotechnology, new insights into genome evolution and combining forces in mathematics. The NWO has awarded grants to these three innovative Leiden research projects in the ENW-M Open Competition.

It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden PhD candidate Samuel Schwab has found that the histones in these organisms are much more diverse than previously thought. Schwab and his colleagues describe…

Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.

Leiden biologists have found a mutation in flour beetles that allows them to speed up their development. The study has been published in Nature Ecology and Evolution.

Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…

What are the costs involved in studying abroad and how can you finance your stay? Avoid unexpected expenses by researching financial matters thoroughly in advance.

Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…

Organisation

Neele Boelens is a board member at DWARS, the youth organisation of political party GroenLinks. In addition, she is studying towards two degrees at Leiden University: Linguistics and Public Administration. A busy year, especially with the upcoming elections.

With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…

An evolutionary 'trap' that has haunted crested and marbled newts for 25 million years: Leiden researchers have uncovered a mysterious DNA error that should not be able to arise – yet persists all the same. How is that possible? PhD candidate James France found new clues.

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On 26-28 June, 2023, Leiden University’s Institute for History will host a summer school on Socioeconomic diplomacy and global empire building, 16th-19th centuries, in collaboration with the N.W. Posthumus Institute (the research school for economic and social history in the Netherlands and Flanders)…

On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…

Biologist Nataliia Machushynets felt like she was ‘looking for a needle in a haystack’, trying to find new antibiotics to help solve the problem of resistance. During her PhD research, she did find what she was looking for, in the soil beneath our feet.

Two consortia led by Leiden researchers have been awarded over one million euros by the Dutch Research Council and the Ministry of Health, Welfare and Sport to find solutions to antimicrobial resistance.

In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…

Transferring poo from healthy donors to the intestines of chronically ill people has beneficial effects on these recipients’ gut bacteria, also in the longer term. This is the conclusion of research by the Leiden University Medical Center (LUMC) and the Netherlands Donor Feces Bank (NDFB).

Collaborating and learning from other fields – that is what bioinformatician Hannah Augustijn enjoys most about doing research. During her PhD at Leiden University, she developed new ways to search within bacteria for the antibiotics of the future.

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

It is still unclear how the Neanderthals died out. For long, one theory seemed most likely: the emergence of the highly intelligent Homo sapiens, or modern humans. This competition hypothesis is no longer the dominant theory among scientists, research among archaeologists and anthropologists has shown.…

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

Effectively treating a severe case of pneumonia is often challenging. Identifying the pathogen behind it can be difficult. PhD candidate Ilona den Hartog tried something new: ‘We searched for answers in substances our own body produces.’ PhD defence on 17 September.

Rapid developments in DNA techniques allow researchers to find out more and more about human genetics. An international group of scientists has drawn up five ethical guidelines to ensure that this DNA research is better regulated. Leiden archaeologist Marie Soressi – one of the signatories - explains…

We need to dispel the arrogant and misguided idea that modern humans are superior to earlier human species. It is thanks in part to all our predecessors such as Neanderthals that we are who we are today. This is what Marie Soressi, Professor of Hominin Diversity Archaeology, will argue in her inaugural…

In July, Leiden will be hosting the EuroScience Open Forum conference. Humanities scholars from Leiden will make use of the opportunity to stress the importance of art in science. ‘Artists have the ability to show the consequences of science.’

Festival