Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.

This book underscores the interplay between religion and politics (local and global) in the production, escalation, management, mitigation, and resolution of conflict.

Fake news is becoming more and more prominent now that social media allow for an endless stream of unfiltered content to reach us. But what happens if we can no longer distinguish the truth from the lie?

Can small molecule drugs restore the immune system’s ability to fight tuberculosis by boosting autophagy?

What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

How do lipases in Mycobacterium tuberculosis help the bacteria survive, and can we target them to create new antibiotics?

Political Scientist Valentina Carraro (Leiden University) devises a framework to assess the degree to which United Nations human rights bodies provide duplicating or contradicting recommendations to states. Focusing on the case of torture, she creates an original database of recommendations delivered…

This article devises a framework to assess the degree to which human rights bodies provide duplicating or contradicting recommendations to States. Focusing on the case of torture, it creates an original database of recommendations delivered to 14 countries in the years 2012–2016. Results show that duplications…

On 3 December 2019, Hanna Bosdriesz defended her thesis 'Furthering the fight against impunity in Latin America: the contributions of the Inter-American Court of Human Rights to domestic accountability processes'. The doctoral research was supervised by Prof. L.J. van den Herik and Prof. M.A.H. van…

The project investigates the changing local context of crime dynamics and the responses by selected international organizations and national governments. It places a major emphasis on security management at the trans-national level by investigating intra-regional security cooperation between Latin America,…

How did “free agents” (entrepreneurs operating outside of the myriad of interests of the centralized, state-sponsored monopolies) in Western Europe and the Ottoman Empire react to the creation of colonial monopolies (royal monopolies and chartered companies) by the central states in the Early Modern…

PhD student Esmee Koedoot studied the underlying processes responsible for metastases in a dangerous type of breast cancer. She hopes to find new possibilities to fight the disease. In December 2019 she obtained her doctorate cum laude.

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

With a Vici grant of 1.5 million euros, Professor of Mathematical biology Roeland Merks will look for ways to fix messy and leaky blood vessels in tumours. His research combines mathematical simulations and lab experiments in a unique way.

Gathering and distributing patient data can make an important contribution to containing the coronavirus. But if we want to be successful, we need better data. With this objective in mind, Leiden data stewards have joined the Virus Outbreak Data Network (VODAN).

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

Who knows more about environmental governance: a professor of natural resource governance or a local shaman in the remote uplands of Myanmar?

‘Be yourself. Be as gay, queer, trans as you can and show the world you exist.’ These rousing words from Looi van Kessel marked the start of the third Pride Leiden for the university boat, with the theme: ‘450 years of being yourself’.

The interdisciplinary, English-taught minor ‘Violence Studies’ looks at violence from very diverse scientific perspectives. What are the benefits from this approach? Students and lecturers evaluate: ‘This minor’s a goldmine’.

Chemotherapy that does not harm the body, but effectively fights cancer cells: that is the goal of chemist Sylvestre Bonnet and his team. During his PhD research, chemist Xuequan Zhou brought that goal a little closer. He developed molecules that, upon injection in the bloodstream, self-assemble into…

The university may seem a bit subdued in the run-up to the Dutch elections on 29 October. The media has barely mentioned education as an election issue, but behind the scenes the university is lobbying hard, says acting President of the Executive Board, Timo Kos. ‘We’re fighting for the future of our…

In July 2019 Asser Press published the book 'Sweetie 2.0—Using Artificial Intelligence to Fight Webcam Child Sex Tourism’ which was coedited by Simone van der Hof en Bart Schermer from the Center for Law and Digital Technologies, Bert-Jaap Koops from the Tilburg Institute for Law, Technology, and Society…

A tax on CO2 emissions from products entering the EU offers unprecedented opportunities in the fight against global warming. That is the conclusion of research on which Leiden environmental scientist Hauke Ward collaborated. ‘A new world is opening up,’ Ward says. ‘But success hinges on how we involve…

From ransomware to Citrix traffic jams: over the past few months Dutch organisations were regularly brought to a standstill by serious cyber attacks. We can only face these threats by standing as one, and universities and government should take the lead. These are the words of Leiden professors Bibi…

'The EU should not give way under pressure as the war continues,' writes Joris Larik, assistant professor of European law, in an opinion piece that was recently published in Dutch newspaper FD.

Understanding what motivates foreign fighters to go and fight in war zones and analysing their social environment offers a basis for preventing them from going.

Leiden University celebrated its 445th foundation day on 7 February 2020.

Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…

The Latin America and Caribbean Security and Intelligence Network (LACSIN) brings together scholars, practitioners, government agencies and the diplomatic community to develop novel and interdisciplinary approaches to addressing key areas of security and intelligence in Latin America and the Caribbe…

This project aims to provide evidence-based knowledge on the conditions for successful anti-corruption activism in Ukraine.

The latest news on diversity and inclusion and an overview of coming D&I-activities within Leiden University.

This thesis represents a comprehensive investigation into the control of cancer stemness and metastatic initiation using a combination of advanced zebrafish xenograft models and in vitro assays.

Health workers have always sought ways to fight disease in vulnerable groups in the population. It is now clear that such research also benefits more prosperous countries. African worm infections and innovative thermometers have shown Leiden researchers how to fight diseases of affluence and keep health…

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

The digitisation of society is a worldwide challenge. Not only are robots increasingly taking over human tasks, they are even beating the world champion at solving the most difficult brainteasers.

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

Team History of Africa and the Americas

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

Bas Rietjens and his colleagues researched the Russia-Ukraine war, exploring this multitude of facets and their interconnections.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

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Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

Bone research provides plenty of detailed data about the health of a person or a group. This data is not only used to reconstruct the past but also to fight disease today.