The LUMC Flow Cytometry Core Facility accommodates all research and diagnostic flow cytometry equipment of the LUMC.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

An overview of our infrastructure at the SPP division:

This is a facility where research groups or small companies can apply for space if they need to culture human or animal cells.

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, a treatment already exists.

Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele

Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.

Promotor: Prof.dr. M.L. van Hecke

Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

Marieke Liem, Professor Social Resilience and Security at Leiden University, and Katharina Krüsselmann, PhD candidate at Leiden University and Manuel Eisner mapped the flow of homicide cases with the help of a systematic review.

This project suggests a reconceptualisation of pre- and non-capitalist imperial monetary policy, arguing that the existing literature about imperial financial flows has unnecessarily privileged ideas of largesse and seemingly chaotic monetary distribution.

This project aims to improve transparency in the distribution of research funding in the world, with a focus on global inequalities. Through an analysis of funding flows, the project will identify inequalities and opportunities for more appropriate and fairer allocation, highlighting patterns that perpetuate…

This subproject argues for a close and forensic reconstruction of financial flows to and from Soviet Central Asian republics in the postwar period.

This project addresses the occurrence of political and ideological biased crimes in light of the recent migration influx in European countries.

How do Central African refugees navigate through uncertainty in a new and hostile environment in the DR Congo?

The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.

This project aims at providing a broad perspective of the state of Science Technology and Innovation (STI) in Africa with a focus on global funding flows, in order to inform research funders in the continent, in particular those participating in the Science Granting Councils Initiative (SGCI). The project…

The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…

This thesis describes a study from both a theoreticaL and an experimental point of view.

Key publications of the Cardiovascular Pharmacology group

We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.

Topology is an emerging field within many scientific disciplines, even leading to a Physics Nobel Prize in 2016. Leiden physicist Marcello Caio and his colleagues have now discovered the existence of topological currents in analogy to electric currents. Publication in Nature Physics on January 14th.

The overarching goal of this thesis is to set the foundations, but also make the first essential steps towards establishing a comprehensive, mesoscopic, hydrodynamic theory of epithelial tissues. The stage is set by an exhaustive study of topological defects in passive p-atic liquid crystals, singularities…

What types of construction materials are used in the Global South, where are they, and what levels of societal services do they support? How will material use evolve under different development pathways and paradigms? What are these materials' environmental and societal impacts now and in the future,…

Science Magazine has published three back-to-back papers on an important discovery in solid state physics. Leiden physicist Jan Zaanen wrote a Perspective article on the subject in the same issue of 4 March.

What are the environmental impacts of widespread integration of bio-based products into the construction industry?

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

Theoretical physicist Luca Giomi receives a 2 million euro ERC Consolidator Grant for research into flowing cells in a strange hexatic phase, which is half fluid, half solid.

Publication in Proceedings of the National Academy of Sciences.

Dr. Van Eijk will teach an advertising technology Masterclass for the Future of Privacy Forum (FPF) next week. It is the fourth session of the FPF & Brussels Privacy Hub's Digital Data Flows series. Van Eijk will be teaching alongside Adam Towvim (Brandeis International Business School) and moderated…

Leiden during corona, loneliness in the elderly or making the city more sustainable. Students from Leiden University and Leiden University of Applied Sciences are working with the Municipality of Leiden on solutions to societal problems. How is this benefitting society? And where is there room for i…

Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.

The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Researchers Indu Khatri, Frank Staal and Jacques van Dongen from Leiden University Medical Center (LUMC) have published a perspective article in Frontiers in Immunology about coronavirus and its characteristic ‘spike protein.’ They predict which antibodies would provide the best protection against the…

On 30 May, GTGC Seed Grant Project 'The Governance of European Textile Waste Export' organised a workshop to engage with key stakeholders in the field.

World history is often framed in terms of flows of people and migration: humans coming ‘out of Africa’, the spread of farmers in the Holocene, Phoenician and Greek diasporas over the ancient Mediterranean, the colonization of the world by Europeans from the 16th century onwards. Together with his Exeter…