Career and apply for jobs

How can we combat the growing global health crisis of antibiotic resistance? At Leiden University, researchers are tackling this issue from multiple angles. PhD candidate Vladyslav Lysenko develops and redesigns new antibiotic molecules, while Sebastian Tandar studies how we can use existing antibiotics…

Give organisms like plants and animals the freedom to move, interact and meet their own needs, and they will thrive on their own, says Professor Geert de Snoo. Our interference often ends up doing more harm than good.

Researchers at Leiden University have created a unique model that mimics how disease develops after a dengue infection. This 'dengue-on-a-chip' model helps them study the virus more effectively. The timing is crucial, as climate change is causing dengue to spread worldwide.

Lecture, NGL-lezing

Researchers from Leiden University, University of York, University of Barcelona/IQTCUB/ICREA and The Francis Crick Institute report a new class of experimental compounds that powerfully block influenza viruses. The findings offer a potential new strategy for treating flu infections and preparing for…

Using mathematics to help children with bone cancer. It sounds a little strange, but for statistician Marta Fiocco, it's just her job. She gets a substantial grant from KiKa for it. With that money, she is going to study the effect of chemotherapy adjustments.

Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.

Study abroad: where and when?

Packages of DNA strands containing silver, measuring just two or three nanometres in size. Leiden physicists Donny de Bruin and Dirk Bouwmeester create these packages, which can enter living cells on their own. They then activate the silver with light, causing the cells to break down. This could, in…

Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.

The AtheroNeth consortium received €6 million from the Dutch Heart Foundation to gain a better understanding of the differences in disease progression among patients with atherosclerosis. The ultimate goal is to enable personalised treatment.

Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…

An international team of astronomers led by Ardjan Sturm of the Observatory has made the first two-dimensional inventory of ice in a planet-forming disk of dust and gas surrounding a young star. The researches, including Melissa McClure, used the James Webb Space Telescope and publish their findings…

Not only dark matter, but also ordinary matter and dark energy are tracked in the largest ever cosmological computer simulation ever. In the FLAMINGO simulations, you can see virtual galaxies and clusters of galaxies emerging over the course of billions of years. This is no easy task: with more than…

A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…

How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…

Could water be present in planet-forming disks before the formation of rocky planets? The James Webb Space Telescope may have found evidence for that. Webb has for the first time observed water in the inner disc around young star where at greater distance, giant planets have already formed. The research…

Leiden PhD candidate Mona Shahab climbed Mount Everest two years ago to raise money for the education of disadvantaged children in Egypt. She made it to the top and posed there with the University flag. She recently presented the flag to Rector Carel Stolker.

Three fundamental research projects at Leiden in physics, chemistry and medical science have received funding from the Dutch Research Council (NWO). They involve research on magnetic fields in the universe, the role of myeloid cells in cancer immunotherapy and the evolution of ancient proteins.

A CT scanner to treat eye cancer, energy-efficient software for the future and a test to identify male chick eggs. Three projects by researchers from Leiden University are to receive funding from research funder NWO’s Open Technology programme, to which the business sector also contributes.

A team of international researchers led by Tomas Stolker in the Netherlands has imaged a young gas giant exoplanet near a 12-million-year-old star. The planet is orbiting a star at which planet formation has finished, while the same-aged companion star still has a planet-forming disk. The researchers…

In the disk surrounding the young star WISPIT 2, not one but two planets are taking shape. Leiden PhD candidate Richelle van Capelleveen played a key role in this discovery, providing a rare glimpse into the early stages of planetary system formation.

Astronomers have measured the mass of a dormant, supermassive black hole in the early universe for the first time. Thanks to a combination of the James Webb Space Telescope and a natural cosmic magnifying glass, researchers were able to weigh the black hole directly based on its gravity.

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…

Could we stop cancer cells by cutting off their energy supply? That’s what Dione Blok, a bachelor’s student in Bio-Pharmaceutical Sciences, aimed to find out during her thesis research. She investigated a compound that affects the tumour cells’ energy metabolism. ‘Hopefully, these insights will provide…

In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…

The more data from cancer research we pool, the better we can search for new treatments. But how can we keep patient data safe when sharing it? Leiden researchers will tackle this challenge in a major European project.

The antibiotic EVG7, developed in Leiden, has proven capable of fighting the dangerous gut bacterium C. difficile with only a minimal dose. What’s more, the bacterium is far less likely to return, a major issue with existing antibiotics. The research was published in Nature Communications.

A Dutch consortium has received €6.7 million to accelerate the development of nanomedicines together with patients. Researchers from Leiden University play a key role in the project.

Five consortia within the Perspectief programme that include Leiden researchers have received funding to start their research projects. These projects focus on (further) developing technological innovations, with societal and economic impact at their core.

One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.

Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'

The Dutch Research Council (NWO) has awarded Vidi grants to Leiden researchers.

Researchers have discovered the most distant Milky-Way-like galaxy yet observed. Dubbed REBELS-25, this disc galaxy seems as orderly as present-day galaxies, but we see it as it was when the Universe was only 700 million years old. This is surprising since, according to our current understanding of…

Astronomers led by Leiden PhD candidate Richelle van Capelleveen have, for the first time, discovered an exoplanet that has carved a bright gap in the protoplanetary disc around its star. This rare observation provides new insights into how young planets shape their surroundings.

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

Leiden scientists lead COLIBRE, a groundbreaking set of cosmological simulations. By including key missing physics, cold gas and cosmic dust, they offer the most realistic picture yet of how galaxies formed and evolved since the dawn of time.

Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

Mathematics can help predict thrombosis. Mathematician Mark Alber has developed models that even aid in suggesting treatments. In the Kloosterman lecture on 27 June, he will explain how this works.

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…

The promising early results of an international study have shown that insulin-producing cells grown from stem cells can cure the disease. The new Cure One LUMC research centre aims to accelerate this breakthrough.

An impressive 22 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).

Astronomers led by Simon Portegies Zwart used simulations to reconstruct how three stars were ejected from the star cluster R136, 60,000 years ago. The analysis reveals that five stars were involved in the event in the Tarantula Nebula.

The shock wave triggered by one of the five galaxies making up the iconic Stephan’s Quintet appears to be less disruptive than previously thought, with the shock likely being cushioned by dust particles in the surrounding gas. This is according to the analysis of the first scientific observations of…

For the first time, astronomers have observed in three dimensions that gas from spiral galaxies is blown upwards and downwards at high speed, far out of the galaxy. They thereby confirm the theory of galaxy evolution: that star-forming galaxies create intergalactic gas flows by discharging gas along…

When a bacterium becomes resistant to one antibiotic, it may sometimes become more sensitive to another. This biological side-effect offers an unexpected opportunity in the fight against antibiotic resistance.