330 search results for “cell” in the Student website
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From nanoscale to whole organism: at the Cell Observatory, researchers study life in detail
About forty microscopes, various laboratories, and some 15,000 zebrafish: that’s Sylvia le Dévédec's workplace. She is one of the managers of the Leiden Cell Observatory, a unique facility accessible to all researchers.
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Micha DrukkerFaculty of Science
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Dennis ClaessenFaculty of Science
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Willem FibbeFaculty of Medicine
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Douwe AtsmaFaculty of Medicine
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Frank SchaftenaarFaculty of Science
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Medical milestone at LUMC: first Dutch patient receives CAR T-cell therapy for autoimmune disease
The LUMC has become the first institution in the Netherlands to treat a patient with an autoimmune disease using CAR T-cell therapy.
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How cells talk by pulling on a fibre network
Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…
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Bacteria without cell wall gobble up DNA from environment
A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…
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Greater understanding of specialised cell could prevent strokes
Ilze Bot wants to reduce the prevalence of cardiovascular diseases. Her research focuses on mast cells, which protect us from infections but can also make us ill.
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How cells work together: the mathematics behind biological shapes
How do biological cells join forces to form a structure? In her PhD research, Daphne Nesenberend uses mathematics to show how forces and cooperation between cells create structure – and how simulations and experiments can reinforce each other.
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Tessa VergroesenFaculty of Science
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Luuk ReinaldaFaculty of Science
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Erik DanenFaculty of Science
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Noortje DannenbergFaculty of Science
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Ewa Snaar-JagalskaFaculty of Science
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Joost BeltmanFaculty of Science
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Christine MummeryFaculty of Medicine
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forming embryo to cancer metastasis: the significance of collective cell movement
Luca Giomi has the first results of his ERC consolidator grant. He discovered that epithelial cells move collectively but in different ways, depending on the scale you look at. It is hexatic at small scales, and becomes nematic at larger scales: it is a multiscale order. This collective movement of…
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Stiffness and viscosity of cells differ in cancer and other diseases
During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.
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LUMC receives tens of millions for research into new stem cell-based treatments
Leiden University Medical Center (LUMC), as a partner in the reNEW consortium, is once again receiving tens of millions of euros for research into new treatments based on stem cells. The collaboration will receive a total of €150 million to develop new therapies in regenerative medicine.
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What does a cell eat? This new tool makes it visible
What if you could watch a single cell eat in real time? This could answer questions about diseases such as cancer. PhD candidate Yixuan Wang has developed a glowing chemical tool that makes this possible, revealing how living cells take in nutrients.
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Marjolein CrooijmansFaculty of Science
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How cells determine the fate of proteins (and can we do it too?)
Cells in our bodies are often threatened by errors in our own proteins. The FLOW consortium, comprising scientists from various institutions including Leiden, is poised to meticulously map out for the first time how cells control proteins, correcting or removing faulty ones. This endeavour holds promise…
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collagen to canvas: interactive artwork brings the world between our cells to life
What’s really happening in the space between the cells in your body? With the Collagen Canvas project, students from Leiden University invite you to explore this question by blending science with art. This interactive artwork immerses you in the dynamics of the extracellular matrix—the invisible structure…
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Arthur RamFaculty of Science
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How to hijack natural destruction in cells: ‘We need to understand it through and through’
Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…
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Tunnel vision alarm in the search for more efficient hydrogen cells
A tenacious postdoc researcher persuaded Professor Marc Koper to research the oxygen reduction reaction. In Koper's eyes, there was little of interest there. But they promptly discovered a whole new way to improve fuel cells on hydrogen and oxygen. Their article appeared in Nature Catalysis on 07 Ju…
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Leiden chemists discover new ways in which single-celled organisms organise their DNA
It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden PhD candidate Samuel Schwab has found that the histones in these organisms are much more diverse than previously thought. Schwab and his colleagues describe…
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Saloni SaxenaFaculty of Science
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technique uncovers disease-related changes in tiny droplets within our cells
Understanding the behaviour of tiny droplets in our cells could aid the search for new treatments. A team of Leiden researchers has developed a groundbreaking method to study how these droplets transition from liquid to solid. This change plays a role in various diseases, including neurodegenerative…
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Serkan AslanFaculty of Science
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Joey ZuijderveltFaculty of Science
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Bas ter BraakFaculty of Science
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Peter BouwmanFaculty of Science
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Sylvia Le DévédecFaculty of Science
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A tail with a twist: how the tokay gecko grows a completely new body part
When the tokay gecko loses its tail, a new one grows from resident stem cells at the stump. Each tissue type - muscle, bone, blood vessels and skin - develops from specific stem cells. This discovery by Luthfi Nurhidayat holds potential implications for advancing regenerative medicine in humans. Nurhidayat…
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Remko OffringaFaculty of Science
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Max FernkornFaculty of Science
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Eliane ZügerFaculty of Science
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Rafaella BuzatuFaculty of Science
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Jingchao WuFaculty of Science
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Andreea IosifFaculty of Science
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Yubin GuoFaculty of Science
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Christian SchröterFaculty of Science
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Daan VlemmingsFaculty of Science
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Ruben de VriesFaculty of Science
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Nina SchultenFaculty of Science
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Ferdinand TeichertFaculty of Science