Central in coordination and organometallic chemistry is the synthesis of new chelating ligands, the synthesis and characterization of metal complexes with these ligands, and the study of their properties. An important goal in my research is to create understanding of the relation between the structures…

LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.

This article explores how to think about solidarity, considering the diverse stories, spaces, practices, bodies, and temporalities that shape a city.

Negative perceptions of ambiguous social cues, social performance and physical arousal in socially anxious youth

The interdisciplinary programme Social Resilience & Security is inviting proposals for seed funding. The programme aims to combine knowledge and expertise from five different faculties to study transgressive behaviours, its dimensions, aetiology, and effects of interventions with a multidisciplinary…

Are you interested in taking up an extra challenge during your master’s programme?

The call for a social media ban for children is louder than ever. Professor of Children's Rights Ton Liefaard argues in ‘Trouw’ newspaper that this would be unwise. 'For children, online and offline aren't different worlds'.

Your time in Leiden is about more than just studying. Some of your best experiences will come from being part of our vibrant and diverse student community, and from living in the beautiful city of Leiden.

Here I propose to study the relationship between autonomic pupil-synchronisation and trust, at the behavioural and neural level, and examine a targeted set of possible contextual moderators.

Samir Negash, PhD candidate at Leiden University and Olaf van Vliet, Professor by special appointment Comparative Welfare State Analysis at Leiden University wrote a paper regarding the topic of immigration and the conditionality of unemployment benefits in OECD countries.

Development & demonstration of low environmental impact innovation and optimization practices in pharma production.

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars (exoplanets). They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems. This way they address…

best phd theses of the faculty of science Leiden - physics, chemistry, computer science, biopharmaceutical sciences, biology, industrial ecology, environmental sciences, astronomy, mathematics. thesis

The surface and the edges of graphene are expected to provide higher sensitivity and specificity in detecting and characterizing single molecules. However fundamental physical limits exist in reaching an ultimate precision in detecting the dynamics of chemical and biological systems. The research in…

The Australian parliament passed a law banning social media for youth under sixteen in late November. This solves nothing, argues Simone van der Hof, Professor of Law and Digital Technologies, in NRC. ‘Services should be held to the law.’

This project investigates which aspects of social media content adolescents attend to and how these relate to their credibility judgments, aiming to systematically understand their susceptibility to misinformation and inform effective educational programs that foster youth’s resilience to misinforma…

On the first day at a new job, you have sweaty palms, nerves race through your system, and you feel insecure. Now, a couple of months later these feelings have left. You know what to do in your new role and have become part of the organization. The process leading to this result is called organizational…

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

This project aims at determining the market value of hydrogen peroxide (HP) that is produced via our electrochemical methods that have been developed as part of the ERC-StG Cu4Energy project.

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Promotor: Prof.dr. J.P. Abrahams

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

Promotor: M. Ubbink, Co-promotor: G. Siegal

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen

The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.

This thesis focuses on the design and synthesis of activity-based probes and inhibitors targeting enzymes involved in the degradation of specific plant glycans.

Assistant Professor at the Department of Analytical Chemistry, Radboud University Nijmegen, the Netherlands

This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals

Promotor: G. A. van der Marel, Co-promotor: D. V. Filippov

MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.

Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…

Promotor: Prof.dr. M. Ubbink

We report new computational and experimental evidence of an efficient and astrochemically relevant formation route to formaldehyde (H2CO). This simplest carbonylic compound is central to the formation of complex organics in cold interstellar clouds and is generally regarded to be formed by the hydrogenation…

Hydrogen peroxide (H2O2) is an important bulk chemical that is used in various industrial processes. More than 95% of the H2O2 used in industry is made via the anthraquinone process during which a large amount of energy is going to waste.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Before the large scale use of renewable energy sources can be implemented in our society, the storage of electrical energy needs to be tackled. Storage the energy as hydrogen via the reduction of protons is a good option.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.