A team of laboratory astrophysicists from Leiden University managed to make glycerol under conditions comparable to those in dark interstellar clouds. They allowed carbon monoxide ice to react with hydrogen atoms at minus 250 degrees Celsius. The researchers publish their findings in the Astrophysical…

The government is investing 646 million euros and has set aside a further 3.5 billion to drive economic growth in the Netherlands. Much of the National Growth Fund will be used for scientific innovations. Leiden University is involved in three of the projects.

On Friday 17 April Leiden Mayor Henri Lenferink will officially open the new Metabolomics Facility of Leiden University. The facility’s ultimate goal is to prevent disease and to improve health throughout the human lifespan.

As far as Daniël Pijnappels, Professor of Cellular Electrophysiology, is concerned, both researching and inventing are essential for a scientist.

Dutch researchers have developed a new tool to label DNA for studying chromosomes in live cells. The tool is non-invasive and can be applied in culture but also in living organisms, such as zebrafish embryos. The team published their findings in the journal Nucleic Acids Research.

Professor by Special Appointment of Clinical Neuropharmacology Geert Jan Groeneveld will deliver his inaugural lecture entitled ‘The importance of the biomarker’ on 11 March 2022. According to him, new genetic knowledge will revolutionise drug research.

Medical Delta has appointed seven professors who will bridge the medical worlds of Leiden, Delft and Rotterdam.

For nine years he worked on the three-volume standard work Plant Galls of Europe. It yielded 2300 pages about 10,000 species of European galls, abnormal outgrowths in plants caused by parasites. Hans Roskam from the Institute of Biology Leiden: ‘The abundance of galls says something about the natural…

When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…

Former dean and physicist Frans Saris writes in his new book ‘Darwin’s combination lock’ how our culture enabled us to dominate nature and about the corresponding responsibilities. Together with Joris Berkhout he will talk about his book during the This Week’s Discoveries on 27 February.

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.

Tropical butterflies adapt to their environment to improve their chances of survival. The changes are triggered by hormone signals that transmit information about temperature to the butterflies' tissues. Biologist Ana Rita Mateus shows how a complex combination of environment, physiology and genetics…

The Dutch X-omics Initiative has received seventeen million euros from NWO as part of the National Roadmap for Large-Scale Infrastructure. Leiden University’s metabolomics research led by Thomas Hankemeier is one of the participators.

Leiden University Medical Center (LUMC), as a partner in the reNEW consortium, is once again receiving tens of millions of euros for research into new treatments based on stem cells. The collaboration will receive a total of €150 million to develop new therapies in regenerative medicine.

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The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.

Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…

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A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.

Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…

The discovery in 2001 of the importance of microRNAs turned the world of molecular biology upside down. The small particles of RNA also attracted the attention of university lecturer Erno Vreugdenhil. Vreugdenhil: ‘Within five to ten years the first microRNA-directed medicines will come onto the mar…

16 April was a special day at the Faculty of Science. In honour of the collaborations with the Chinese partner university, it was declared Xi’an Jiaotong University Day.

Human measures to protect lions have an impact on the genetic health of populations. Leiden and Kenyan scientists discovered this by analysing the DNA of 171 Kenyan lions. ‘By fencing reserves, for example, the chance of inbreeding increases.’ With the knowledge and tools from the research, management…

Patients with the same illness often receive the same treatment, even if the cause of the illness is different for each person. This represents a new step towards ultimately being able to offer every patient more personalised treatment.

The use of the pill, in combination with genetic factors, can influence experimental psychological research in women. More research is needed into the influence of the pill on mood disorders, concludes psychologist Daniëlle Hamstra. PhD defence on 30 September.

Researchers from the Plant Ecology and Phytochemistry group at the Institute of Biology Leiden (IBL) received an STW (Stichting Technologische Wetenschappen) grant for applied studies in plant herbivore resistance with potential for a novel resistance test.

Some people are more sensitive to depression than others. But why is that the case? Clinical psychologist Niki Antypa studied how vulnerability to depression is influenced by cognition. She also found a first careful indication that a treatment with omega-3 fatty acids might provide a solution.

The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…

Eleven talented Leiden researchers with several years of research experience have been awarded a Vidi subsidy to set up or expand their own line of research.

Leiden has scored highly with the recent Vici awards. Of the 31 Vici winners announced by NWO, 4 are researchers in Leiden. The winners are: Professor of Family and Child Studies Marian Bakermans-Kranenburg, information scientist Peter Grünwald, astronomer Linnartz and Professor of Buddhism Jonathan…

One of them turned out to be two thousand years old. And older giant barrel sponges appear to have a faster rate of cell division, unlike us. They produce antibiotics and much, much more. Lina Bayona Maldonado studied how the differences in such factors as age or oceanic depth affect the production…

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In otherwise energetic desserts at the bottom of the sea, researchers have found oases where microbes can harvest energy. Remarkably, the microbes first have to be buried under starving conditions for 80,000 years. An international group of researchers, amongst them José Mogollón from the Insitute of…

More effective diagnosis and prognosis than ever, with less intrusive medical screening? Scientists from Leiden, Delft and Rotterdam are well on the way to achieving just that. Imaging professors Serge Rombouts and Wiro Niessen are working on an extremely rigorous, self-learning adviser for radiologists.…

Streptomycetes are similar to moulds, but these bacteria live in the soil. They are very popular in biotechnology because they produce a great many antibiotics and enzymes. Gilles van Wezel will be using his Vici subsidy to study ways of increasing their production.

LCN2 hosts seminars on the last Friday of each month.

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Lecture

Telling sensationalised stories, exaggerating benefits and understating the risks: creating ‘hype’ about something doesn't sound like something a responsible scientist would indulge in. Or could we also use hype in a ‘good way'? What could we achieve by opening up quantum futures for wider discussions,…

Cleveringa Professor Roméo Dallaire led the UN peacekeeping mission in Rwanda in 1994, but was unable to prevent a genocide from unfolding before his very eyes. Eight hundred thousand people lost their lives. In his Cleveringa Lecture on 26 November, this retired Lieutenant-General from Canada speaks…

Rotterdam is an extreme example of inequality in the Netherlands. There are huge health and life expectancy differences between neighbourhoods. Good access to healthcare and education isn’t a cure-all, say inequality economists Lieke Beekers and Hans van Kippersluis